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The map label for this gene is fcbA1 [H]

Identifier: 160874699

GI number: 160874699

Start: 1904800

End: 1906686

Strand: Direct

Name: fcbA1 [H]

Synonym: Sbal195_1582

Alternate gene names: 160874699

Gene position: 1904800-1906686 (Clockwise)

Preceding gene: 160874698

Following gene: 160874700

Centisome position: 35.62

GC content: 49.92

Gene sequence:

>1887_bases
ATGTCGACCTTGCTTGAGACTGAAGTGACTCCTTTGTTGGCTGCTGTAGTGACGCCGTTGGATACGTCACTTTTAACGGG
TACTTCTGCGTCAGCAATGGCCAGTGACGCTAATATTTGTCGTCATCTCAAGCAAGCCGCCCATGCCATTCCCCACCATC
TTGCAGTAGCAGTACAAAGTGCTCAGGGCGCTTCTGTGGCGAATTTGTGTTACAGTGAGTTGGACTTTCTCAATCTAGAC
AGACAAAGCGATGCGATAGCCTTTGCGCTGAACGCCCATGGCATTGAGCGTGGCATGAAAGCTGTGCTTATGGTCACGCC
GAGTCTGGATTTTTTTGCACTCACCTTTGCGCTGTTTAAAGCGGGGATTATTCCTATCCTAGTTGATCCCGGCATGGGTA
TTAACAATCTTAAGCAGTGTTTTGCCGAAGCCGCGCCCGATGCTTTTATTGGTATTCCCAAAGCCCATATCGCCAGACGG
TTATTTGGTTGGGGTAAGGGTAGCATTAAGTCATTGCTCAATGTTGATGGCGGTAAAACTGGCTTACCGGCAAGATTAAT
CCGCATCGCTACTGGCGCTATCAGTTTATCGACTCTGCTGCAAAACAGCTCTTCACGAAACGCCTCGGCTCAACACACCC
AAGCCCAACATGCTGAATATCCCATGGTGATGCTCAAATCTGATGAGATGGCGGCGATTTTATTCACCAGTGGCAGTACC
GGCACGCCTAAGGGCGTAGTGTATAGCCATGGGATGTTTGAGGCGCAAATTAAAGCGTTAAAAAACGATTATGGCATTTG
CCATGGCGAGCGCGATTTAGCGACGTTTCCGCTGTTTTCACTCTTTGGTCCCGCGCTGGGAATGGCGTCGATCGTTCCAG
AAATGGATGCCAGCAAACCCATCACCGCCAATCCCGAATTCCTGTTTGCCGCGATTGAGAAATATCAATGCAGCAACATC
TTTGTTAATCCCGCCTTGCTGGAACGTTTAGGCCGCGCAGGGGAGCAAAAACAGCATAAACTGCCCAGCGTGCAGCGGGT
CATTTCTGCGGGTGCGCCAGCCACCATTGCCTCCATCGCCCGATTTAGCAAGATGCTGAGTCAAGGTGTGCCGATTTTAA
ATTCCTATGGTGCAACCGAATCTTTGCCGATCAGCATGATTGCTAGCGATGCGTTATTTGCCACCACAGACATCACAGAT
AACGGCGGCGGCATTTGTGTCGGCGGCGCTATCGATGGCGTGACGATTCGCATCATCGGCATCAGCGAAGCCGTTATCCC
CGAGTGGGATGAGGCCTTAGTGCTGAATAACGGTGAAATCGGTGAAATCGTGGTGCAGGGGCCTATGGTGAGTCAGTCCT
ATTATCTAAACAATAGTCAACATGATAGGCAAAACGATAGTCAGCACGATAGCCAAGGCAATAGCGCGACTGCGGCGGCC
AAGATGTGGGACTCAGCCACCAATAGCGTTAGGCATCGCATGGGCGATCTCGGGTATCTCGATAATCAAGGCCGACTGTG
GATGTGCGGTCGCAAGGCCCACAGAGTCGATGCCACCCGTAAAGGCCAGTTGGTAAAGCGTTATTATTCCATTCCCTGCG
AGCGCATTTTTAATACCCATCCCAATGTGAAGCGCTCTGCCTTAGTTGGAGTGAAAGTGGCGAACGAGATAGAGCCTTTG
ATCTGTATCGAACTCGACCAATCATTGGTGTGCAATAAGAGCCAACAGCTATATCAAGATTTGATTACCATCGCAGAGCA
ATTTGCCCAGACGCAGGGCATAAGACGTTTTCTTATCCATCCTGATTTCCCTGTGGATGTGCGACATAATGCCAAGATTT
TTAGAGAAAAATTAGCCGTTTGGGCACAATCACAAACGAAAGGTTGA

Upstream 100 bases:

>100_bases
ACTACATTCTGGAAGACGCCAGCGATGAAGTGATTGCTCATATCAAGAGCTTTATGGCCGACGACCAAGCTGCGGCGCCG
TCCGAACAGGCCGCAGGTTA

Downstream 100 bases:

>100_bases
TTTATACCCAAACAGCCTGAAAATGCAGGATTCAGCGGGCGGTTAACGTACTTTAGGCAAGGCGGCTATTTGCAGACCTA
GTGGACTAAGTTAAAAATAG

Product: peptide synthase

Products: NA

Alternate protein names: 4-CBA:CoA ligase [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSTLLETEVTPLLAAVVTPLDTSLLTGTSASAMASDANICRHLKQAAHAIPHHLAVAVQSAQGASVANLCYSELDFLNLD
RQSDAIAFALNAHGIERGMKAVLMVTPSLDFFALTFALFKAGIIPILVDPGMGINNLKQCFAEAAPDAFIGIPKAHIARR
LFGWGKGSIKSLLNVDGGKTGLPARLIRIATGAISLSTLLQNSSSRNASAQHTQAQHAEYPMVMLKSDEMAAILFTSGST
GTPKGVVYSHGMFEAQIKALKNDYGICHGERDLATFPLFSLFGPALGMASIVPEMDASKPITANPEFLFAAIEKYQCSNI
FVNPALLERLGRAGEQKQHKLPSVQRVISAGAPATIASIARFSKMLSQGVPILNSYGATESLPISMIASDALFATTDITD
NGGGICVGGAIDGVTIRIIGISEAVIPEWDEALVLNNGEIGEIVVQGPMVSQSYYLNNSQHDRQNDSQHDSQGNSATAAA
KMWDSATNSVRHRMGDLGYLDNQGRLWMCGRKAHRVDATRKGQLVKRYYSIPCERIFNTHPNVKRSALVGVKVANEIEPL
ICIELDQSLVCNKSQQLYQDLITIAEQFAQTQGIRRFLIHPDFPVDVRHNAKIFREKLAVWAQSQTKG

Sequences:

>Translated_628_residues
MSTLLETEVTPLLAAVVTPLDTSLLTGTSASAMASDANICRHLKQAAHAIPHHLAVAVQSAQGASVANLCYSELDFLNLD
RQSDAIAFALNAHGIERGMKAVLMVTPSLDFFALTFALFKAGIIPILVDPGMGINNLKQCFAEAAPDAFIGIPKAHIARR
LFGWGKGSIKSLLNVDGGKTGLPARLIRIATGAISLSTLLQNSSSRNASAQHTQAQHAEYPMVMLKSDEMAAILFTSGST
GTPKGVVYSHGMFEAQIKALKNDYGICHGERDLATFPLFSLFGPALGMASIVPEMDASKPITANPEFLFAAIEKYQCSNI
FVNPALLERLGRAGEQKQHKLPSVQRVISAGAPATIASIARFSKMLSQGVPILNSYGATESLPISMIASDALFATTDITD
NGGGICVGGAIDGVTIRIIGISEAVIPEWDEALVLNNGEIGEIVVQGPMVSQSYYLNNSQHDRQNDSQHDSQGNSATAAA
KMWDSATNSVRHRMGDLGYLDNQGRLWMCGRKAHRVDATRKGQLVKRYYSIPCERIFNTHPNVKRSALVGVKVANEIEPL
ICIELDQSLVCNKSQQLYQDLITIAEQFAQTQGIRRFLIHPDFPVDVRHNAKIFREKLAVWAQSQTKG
>Mature_627_residues
STLLETEVTPLLAAVVTPLDTSLLTGTSASAMASDANICRHLKQAAHAIPHHLAVAVQSAQGASVANLCYSELDFLNLDR
QSDAIAFALNAHGIERGMKAVLMVTPSLDFFALTFALFKAGIIPILVDPGMGINNLKQCFAEAAPDAFIGIPKAHIARRL
FGWGKGSIKSLLNVDGGKTGLPARLIRIATGAISLSTLLQNSSSRNASAQHTQAQHAEYPMVMLKSDEMAAILFTSGSTG
TPKGVVYSHGMFEAQIKALKNDYGICHGERDLATFPLFSLFGPALGMASIVPEMDASKPITANPEFLFAAIEKYQCSNIF
VNPALLERLGRAGEQKQHKLPSVQRVISAGAPATIASIARFSKMLSQGVPILNSYGATESLPISMIASDALFATTDITDN
GGGICVGGAIDGVTIRIIGISEAVIPEWDEALVLNNGEIGEIVVQGPMVSQSYYLNNSQHDRQNDSQHDSQGNSATAAAK
MWDSATNSVRHRMGDLGYLDNQGRLWMCGRKAHRVDATRKGQLVKRYYSIPCERIFNTHPNVKRSALVGVKVANEIEPLI
CIELDQSLVCNKSQQLYQDLITIAEQFAQTQGIRRFLIHPDFPVDVRHNAKIFREKLAVWAQSQTKG

Specific function: Catalyzes the formation of chlorobenzoyl-CoA via a 2 step reaction. First 4-chlorobenzoate is adenylated by ATP, followed by acyl transfer from the 4-chlorobenzoyl-AMP intermediate to CoA. Benzoate, 4-bromobenzoate, 4- iodobenzoate and 4-fluorobenzoate al

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786529, Length=336, Percent_Identity=25.297619047619, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI145693145, Length=525, Percent_Identity=22.4761904761905, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558820, Length=520, Percent_Identity=20.9615384615385, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319699, Length=333, Percent_Identity=22.8228228228228, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648260, Length=299, Percent_Identity=26.7558528428094, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =6.2.1.33 [H]

Molecular weight: Translated: 67732; Mature: 67601

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLETEVTPLLAAVVTPLDTSLLTGTSASAMASDANICRHLKQAAHAIPHHLAVAVQS
CCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
AQGASVANLCYSELDFLNLDRQSDAIAFALNAHGIERGMKAVLMVTPSLDFFALTFALFK
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCEEEEEEECCCHHHHHHHHHHH
AGIIPILVDPGMGINNLKQCFAEAAPDAFIGIPKAHIARRLFGWGKGSIKSLLNVDGGKT
CCCEEEEECCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCHHHHHHHCCCCCCC
GLPARLIRIATGAISLSTLLQNSSSRNASAQHTQAQHAEYPMVMLKSDEMAAILFTSGST
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEEECCCC
GTPKGVVYSHGMFEAQIKALKNDYGICHGERDLATFPLFSLFGPALGMASIVPEMDASKP
CCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
ITANPEFLFAAIEKYQCSNIFVNPALLERLGRAGEQKQHKLPSVQRVISAGAPATIASIA
CCCCCHHHHHHHHHHCCCCEEECHHHHHHHHCCCCHHHHCCHHHHHHHHCCCCHHHHHHH
RFSKMLSQGVPILNSYGATESLPISMIASDALFATTDITDNGGGICVGGAIDGVTIRIIG
HHHHHHHCCCCEEECCCCCCCCCHHHEECCCEEEEEEECCCCCCEEECCCCCCEEEEEEE
ISEAVIPEWDEALVLNNGEIGEIVVQGPMVSQSYYLNNSQHDRQNDSQHDSQGNSATAAA
CCCCCCCCCCCEEEECCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHH
KMWDSATNSVRHRMGDLGYLDNQGRLWMCGRKAHRVDATRKGQLVKRYYSIPCERIFNTH
HHHHHHHHHHHHHHCCCCEECCCCCEEEECCHHHHCCCHHHHHHHHHHHHCCHHHHHCCC
PNVKRSALVGVKVANEIEPLICIELDQSLVCNKSQQLYQDLITIAEQFAQTQGIRRFLIH
CCCCHHHEEEEEECCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEC
PDFPVDVRHNAKIFREKLAVWAQSQTKG
CCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STLLETEVTPLLAAVVTPLDTSLLTGTSASAMASDANICRHLKQAAHAIPHHLAVAVQS
CCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
AQGASVANLCYSELDFLNLDRQSDAIAFALNAHGIERGMKAVLMVTPSLDFFALTFALFK
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCEEEEEEECCCHHHHHHHHHHH
AGIIPILVDPGMGINNLKQCFAEAAPDAFIGIPKAHIARRLFGWGKGSIKSLLNVDGGKT
CCCEEEEECCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCHHHHHHHCCCCCCC
GLPARLIRIATGAISLSTLLQNSSSRNASAQHTQAQHAEYPMVMLKSDEMAAILFTSGST
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEEECCCC
GTPKGVVYSHGMFEAQIKALKNDYGICHGERDLATFPLFSLFGPALGMASIVPEMDASKP
CCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
ITANPEFLFAAIEKYQCSNIFVNPALLERLGRAGEQKQHKLPSVQRVISAGAPATIASIA
CCCCCHHHHHHHHHHCCCCEEECHHHHHHHHCCCCHHHHCCHHHHHHHHCCCCHHHHHHH
RFSKMLSQGVPILNSYGATESLPISMIASDALFATTDITDNGGGICVGGAIDGVTIRIIG
HHHHHHHCCCCEEECCCCCCCCCHHHEECCCEEEEEEECCCCCCEEECCCCCCEEEEEEE
ISEAVIPEWDEALVLNNGEIGEIVVQGPMVSQSYYLNNSQHDRQNDSQHDSQGNSATAAA
CCCCCCCCCCCEEEECCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHH
KMWDSATNSVRHRMGDLGYLDNQGRLWMCGRKAHRVDATRKGQLVKRYYSIPCERIFNTH
HHHHHHHHHHHHHHCCCCEECCCCCEEEECCHHHHCCCHHHHHHHHHHHHCCHHHHHCCC
PNVKRSALVGVKVANEIEPLICIELDQSLVCNKSQQLYQDLITIAEQFAQTQGIRRFLIH
CCCCHHHEEEEEECCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEC
PDFPVDVRHNAKIFREKLAVWAQSQTKG
CCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA