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The map label for this gene is metA [H]

Identifier: 160874641

GI number: 160874641

Start: 1835509

End: 1836450

Strand: Direct

Name: metA [H]

Synonym: Sbal195_1524

Alternate gene names: 160874641

Gene position: 1835509-1836450 (Clockwise)

Preceding gene: 160874640

Following gene: 160874642

Centisome position: 34.33

GC content: 45.75

Gene sequence:

>942_bases
ATGCCGGTTAGAATTCCAGATCATCTGCCCGCAGCAGAAGTGTTAGAGTCAGAAAATATTTTCGTTATGTCCGAGACGCG
GGCGGCTAATCAAGATATCAGGCCGATGAAGGTGCTGATTTTGAACTTGATGCCGAACAAAATCGAGACAGAAACCCAGT
TACTGCGCTTACTGGGCAACACGCCTTTACAAGTCGATGTGGATTTATTGCGCATTCACGACAAAGAATCCAAGCATACT
TCCATCGATCACATGAATACTTTCTACCGTGACTTTGAAGCCGTGCGCCATAAAAATTACGACGGCCTTATCATCACAGG
TGCGCCGCTTGGGCAAATCGATTTCGAAGATGTAGTTTATTGGGATCATATCCGTGAAATCATCGACTGGTCCCAAGAGC
ATGTCACCTCAGTGTTGTTTTTATGCTGGGCAGCCCATGCGGGTTTATATCATCTCTATGGTTTAAATCGAAAAATATTG
CAACAGAAGCGTTCAGGCGTATTCGTGCATCGCCGTACCTCTCAGCATTTCCCGTTACTGCGCGGTTTTGATGATGAATT
TTTTGCACCCCATTCCCGTTTTGCCGAAATGGATGTCGAAGAAATTAGACAACATCCACAGCTGCAGCTATTGGCCGAGT
CCGATGAGGCAGGGGCTTATTTGGTGTTAAGTCGGAATAATCGTAACTTGTTTGTGATGGGTCATCCTGAATATCAAAAG
TCGACCTTAAACGAGGAATATCAGCGAGACTTAAGCCAAGGTTTAGACCCGAATGTGCCGCAGAATTATTATCGCAATGA
TGATCCTAAAGACGACGCCATTGCCCGCTGGCACAGCCACGGTAGTTTGTTGGTGAGTAATTGGCTTAATTATTACGTCT
ATCAGTTAACCCCTTACGACTTAAGCGATATGACGGCGATGACACCGTGGGAGTCGCGTTAA

Upstream 100 bases:

>100_bases
ACGATACTGCTAGAGAAAGTCGGTGGCTAGTTAGCCCGCTCAGAAGTGAGCTGACATACGCGCCGAATCCGTTGGTATTT
ACGAACAGAAGAGGCGCGGT

Downstream 100 bases:

>100_bases
GGTTTTGTTTAGCCTTTTATGGTGATGTGGTCACATGGATGTGACTTTAGCTGATACCCAAAAGCACTTAATATATCTCT
CCCTTAGAGCCAACCTTCCA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHT
SIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKIL
QQKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQK
STLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR

Sequences:

>Translated_313_residues
MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHT
SIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKIL
QQKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQK
STLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR
>Mature_312_residues
PVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTS
IDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQ
QKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQKS
TLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=304, Percent_Identity=54.6052631578947, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36658; Mature: 36527

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGN
CCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
TPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVY
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
WDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTSQHFPLL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCEEEEECCCCCCCHH
RGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQK
HCCCHHHCCCCHHHHCCCHHHHHCCCCEEEEEECCCCCEEEEEEECCCEEEEEECCCHHH
STLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYD
HHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCEEEEEECCCC
LSDMTAMTPWESR
CCCCCCCCCCCCC
>Mature Secondary Structure 
PVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGN
CCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
TPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVY
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
WDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTSQHFPLL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCEEEEECCCCCCCHH
RGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQK
HCCCHHHCCCCHHHHCCCHHHHHCCCCEEEEEECCCCCEEEEEEECCCEEEEEECCCHHH
STLNEEYQRDLSQGLDPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYD
HHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCEEEEEECCCC
LSDMTAMTPWESR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA