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The map label for this gene is galE [H]

Identifier: 160874630

GI number: 160874630

Start: 1824251

End: 1825264

Strand: Reverse

Name: galE [H]

Synonym: Sbal195_1513

Alternate gene names: 160874630

Gene position: 1825264-1824251 (Counterclockwise)

Preceding gene: 160874631

Following gene: 160874629

Centisome position: 34.13

GC content: 46.65

Gene sequence:

>1014_bases
ATGACGATTTTAGTGACCGGTGGTGCTGGTTATATTGGCACTCACACTGTAGTAGAACTGCTCAATGCTGGCAATGACGT
GATAGTGTTAGACAACTTGTCTAATTCGAGCATAGAAGCCTTAAACAGAGTTGAGCGGATCACAGGTAAATCGGTCATTT
TCTATCAAGGCGATATTCTCAATAAAGCCTTATTACAGAAAGTGTTTAACGATCATGCTATCGATTCGGTTATTCACTTT
GCGGGATTAAAGGCTGTGGGTGAATCCGTCGCTAAACCCCTTAAGTATTATGAGAATAACGTCACAGGAACCCTGATCCT
CTGCCAAGTTATGGCGGAGTTTAAGGTGAAAAATCTCGTTTTCAGCTCATCGGCCACTGTATATGGCGATCCAGCCAGTT
TGCCAATCACCGAAGACTTCCCTACTGGAGCAACCAATCCCTATGGTCAGTCTAAGTTGATGGTTGAACATATACTGGCA
GATGTACACAATGCCGATCCAAGCTGGAATATCGCTCGTCTGCGTTATTTTAATCCTGTCGGCGCCCATGCCAGTGGCTT
AATCGGCGAAGATCCTAACGATATCCCTAACAACTTGATGCCCTTTATTGCGCAGGTTGCCGTGGGTAAACGTGCCGCCT
TAAGCGTGTTTGGTGATGATTATCCGACTCATGATGGGACTGGCGTGCGTGACTATATCCATGTGGTAGATTTAGCCAAT
GGCCATTTAAAAGCACTGGCCAAATTGGCCACTAAACCAGGTCTGGTCACCTATAACTTAGGCACAGGCCAAGGATATAG
TGTTTTAGACATGGTTCATGCCTTTGAAAAAGCCTGTGGTAAGCCTATTGCCTACCAAATTGCGCCACGTCGCCCTGGTG
ATATTGCCGCCTGCTACGCCGATCCAACCCATGCACGGGAAGATCTTGGCTGGCAAGCAACGCATACGCTAGCAGATATG
GCCAACAGTAGCTGGCATTGGCAATCAACCAATCCCAATGGTTATAACGGCTAA

Upstream 100 bases:

>100_bases
AAGGTTACATGCGTGCGAACGTTGAATACGCCCTGCGCCACAGCGAAATCGGTGAAGATTTTGCGCAATATTTAAAAACC
GTTGTAAAAGGGATGAAGTA

Downstream 100 bases:

>100_bases
CAAATTGAATGGCTTGTGGAAATATCCCAAGCCATTTTTCTTTATCACTGTGAATACGCTCATCACTTTAAATAATTAAC
CGTTCGAGGAGCAACATGAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTILVTGGAGYIGTHTVVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAIDSVIHF
AGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DVHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADM
ANSSWHWQSTNPNGYNG

Sequences:

>Translated_337_residues
MTILVTGGAGYIGTHTVVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAIDSVIHF
AGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DVHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADM
ANSSWHWQSTNPNGYNG
>Mature_336_residues
TILVTGGAGYIGTHTVVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAIDSVIHFA
GLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILAD
VHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLANG
HLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADMA
NSSWHWQSTNPNGYNG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=59.1176470588235, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=59.1176470588235, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=59.1176470588235, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI7657641, Length=271, Percent_Identity=27.3062730627306, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=62.797619047619, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI48994969, Length=373, Percent_Identity=27.8820375335121, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=25.8953168044077, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=54.9132947976879, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=54.5977011494253, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17568069, Length=341, Percent_Identity=26.3929618768328, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=52.6315789473684, Blast_Score=368, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=59.7667638483965, Blast_Score=419, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36286; Mature: 36155

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVTGGAGYIGTHTVVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDIL
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHH
NKALLQKVFNDHAIDSVIHFAGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADVHNADPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCC
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYA
CHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DPTHAREDLGWQATHTLADMANSSWHWQSTNPNGYNG
CCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TILVTGGAGYIGTHTVVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDIL
EEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHH
NKALLQKVFNDHAIDSVIHFAGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADVHNADPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCC
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYA
CHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DPTHAREDLGWQATHTLADMANSSWHWQSTNPNGYNG
CCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]