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The map label for this gene is hetI [H]

Identifier: 160874573

GI number: 160874573

Start: 1758047

End: 1759036

Strand: Direct

Name: hetI [H]

Synonym: Sbal195_1455

Alternate gene names: 160874573

Gene position: 1758047-1759036 (Clockwise)

Preceding gene: 160874562

Following gene: 160874574

Centisome position: 32.88

GC content: 47.88

Gene sequence:

>990_bases
ATGATGAACCCAGATAAGAATATTGCTAAGTGCTCTCCAAAAAGCCAGACAATGATAACTCATCAGCCGCAAGGCTTTGT
ACAGCTAGGCTCTCGAATGACCGACTCTCTAACATCTAGCAAAAACGGCGTGAATGTGGATCTGTTTTTTATTCCGCTGA
ACGATATGTCAGCGGCGCAAACATCACTTGCCGAGTCTTGGTTAAGTGATGATGAACTCGCAAAGGTCAGGCGTTATCGC
GATCCCAAGGCGCAAATAAAGGGGTTACAGGTGAGGGCGGCGCTACGGACCGTATTATCTCGCTATGCGGATTTATCGCC
ACATGAGTGGTGTTTTGAATATGGCGCTAAGGGCAAACCGAGTTTAACGGCGACATTAGGGCAGCAAACTGGTCTCGAGT
TTAACCTAAGTCATAGCGGCGATTGGTTATTGATTGGTGTGGCTCAGTTTGATGGCGTTGAGTCTGGTTTATTTGGGGTC
GATATTGAAAGGTCGCGGCCGAAGACGGATATCTATCCAATCCTAAATCACTATTTTTCTCCCCAAGAAACTGCAGCCTT
GCTCGCTCTCGCCGATGAAGCGAGTCAGCGACAGCGCTTTTTCGATTTATGGGCGCTAAAGGAGTCCTATATCAAGGCGA
CTGGACTAGGTTTAGCGCAGTCGCTCAAATCCTTTGCCTTTGAGCTTAAGCCGTTTGAGCAATTGGCGGCAGAATCGCTT
GAGTTATCATGCCAAGATGCCGGATTGAGGCAAGCCTGCGGCGTAGCTTCAATGCTTAATGTTTATCCACATATTCCATT
ACAAGTCCCGCTACAAATCCCAATACACACACTGGATTTAGCTGACTCCTTGCATTGGCAAACGCATTTTGGTCGTTTGA
CCGAGGAGTATCGCTTTGCCATTAGCTTAGCGCATGCCGGTAATGCCGCGCTTCCCATAACGCTAACCGCGCAGTTGAGC
AGCATAGAGAGCTTACTTGCTGATTATTAA

Upstream 100 bases:

>100_bases
GCGTTTAGAGTCGTTCTAAGAATTGCTCTTATTAGAGCGTGGCTAAGAATTGAAATAGGGCTTAGTTGAAACTATTTAAG
ATGCATAATGAACTCAAATA

Downstream 100 bases:

>100_bases
CGGCGAAAGAGAGTGCTTTCTTCGCGCCAGTAAACTCACCTAAACCGCTAAGATCTGCGATTGCGTTTAGCCATAATTCT
TTCTGCGCGTTATCTTGTTA

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MMNPDKNIAKCSPKSQTMITHQPQGFVQLGSRMTDSLTSSKNGVNVDLFFIPLNDMSAAQTSLAESWLSDDELAKVRRYR
DPKAQIKGLQVRAALRTVLSRYADLSPHEWCFEYGAKGKPSLTATLGQQTGLEFNLSHSGDWLLIGVAQFDGVESGLFGV
DIERSRPKTDIYPILNHYFSPQETAALLALADEASQRQRFFDLWALKESYIKATGLGLAQSLKSFAFELKPFEQLAAESL
ELSCQDAGLRQACGVASMLNVYPHIPLQVPLQIPIHTLDLADSLHWQTHFGRLTEEYRFAISLAHAGNAALPITLTAQLS
SIESLLADY

Sequences:

>Translated_329_residues
MMNPDKNIAKCSPKSQTMITHQPQGFVQLGSRMTDSLTSSKNGVNVDLFFIPLNDMSAAQTSLAESWLSDDELAKVRRYR
DPKAQIKGLQVRAALRTVLSRYADLSPHEWCFEYGAKGKPSLTATLGQQTGLEFNLSHSGDWLLIGVAQFDGVESGLFGV
DIERSRPKTDIYPILNHYFSPQETAALLALADEASQRQRFFDLWALKESYIKATGLGLAQSLKSFAFELKPFEQLAAESL
ELSCQDAGLRQACGVASMLNVYPHIPLQVPLQIPIHTLDLADSLHWQTHFGRLTEEYRFAISLAHAGNAALPITLTAQLS
SIESLLADY
>Mature_329_residues
MMNPDKNIAKCSPKSQTMITHQPQGFVQLGSRMTDSLTSSKNGVNVDLFFIPLNDMSAAQTSLAESWLSDDELAKVRRYR
DPKAQIKGLQVRAALRTVLSRYADLSPHEWCFEYGAKGKPSLTATLGQQTGLEFNLSHSGDWLLIGVAQFDGVESGLFGV
DIERSRPKTDIYPILNHYFSPQETAALLALADEASQRQRFFDLWALKESYIKATGLGLAQSLKSFAFELKPFEQLAAESL
ELSCQDAGLRQACGVASMLNVYPHIPLQVPLQIPIHTLDLADSLHWQTHFGRLTEEYRFAISLAHAGNAALPITLTAQLS
SIESLLADY

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 36390; Mature: 36390

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNPDKNIAKCSPKSQTMITHQPQGFVQLGSRMTDSLTSSKNGVNVDLFFIPLNDMSAAQ
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHH
TSLAESWLSDDELAKVRRYRDPKAQIKGLQVRAALRTVLSRYADLSPHEWCFEYGAKGKP
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
SLTATLGQQTGLEFNLSHSGDWLLIGVAQFDGVESGLFGVDIERSRPKTDIYPILNHYFS
CEEEECCCCCCCEEEECCCCCEEEEEEHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC
PQETAALLALADEASQRQRFFDLWALKESYIKATGLGLAQSLKSFAFELKPFEQLAAESL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ELSCQDAGLRQACGVASMLNVYPHIPLQVPLQIPIHTLDLADSLHWQTHFGRLTEEYRFA
CCCHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHEEE
ISLAHAGNAALPITLTAQLSSIESLLADY
EEEECCCCCEEEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MMNPDKNIAKCSPKSQTMITHQPQGFVQLGSRMTDSLTSSKNGVNVDLFFIPLNDMSAAQ
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHH
TSLAESWLSDDELAKVRRYRDPKAQIKGLQVRAALRTVLSRYADLSPHEWCFEYGAKGKP
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
SLTATLGQQTGLEFNLSHSGDWLLIGVAQFDGVESGLFGVDIERSRPKTDIYPILNHYFS
CEEEECCCCCCCEEEECCCCCEEEEEEHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC
PQETAALLALADEASQRQRFFDLWALKESYIKATGLGLAQSLKSFAFELKPFEQLAAESL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ELSCQDAGLRQACGVASMLNVYPHIPLQVPLQIPIHTLDLADSLHWQTHFGRLTEEYRFA
CCCHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHEEE
ISLAHAGNAALPITLTAQLSSIESLLADY
EEEECCCCCEEEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]