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The map label for this gene is ycgM [H]

Identifier: 160874544

GI number: 160874544

Start: 1712144

End: 1712770

Strand: Direct

Name: ycgM [H]

Synonym: Sbal195_1426

Alternate gene names: 160874544

Gene position: 1712144-1712770 (Clockwise)

Preceding gene: 160874542

Following gene: 160874546

Centisome position: 32.02

GC content: 47.37

Gene sequence:

>627_bases
ATGAAATCAGTCGTGTTGGGTGAAAAGCGTATCGTACCGACAAAAATTGTCTGCATTGGACGTAATTATGTCGACCATAT
CCATGAGTTAGGCAATGACATACCCGACGACATGGTGGTGTTTTTAAAGCCCAATTCGGCGATGTCGACTGTGCTGCTTG
CTGAGCATCAAGGTGAAGCCTTGCACTATGAAACCGAGCTGTGTTTTATGTTTCAAGATGGCCGTTTTAGCAGCGTTGCC
ATTGGCTTAGATCTCACTAAACGTGATTTACAAAGTAAGTTAAAAGCCAAGGGATTGCCTTGGGAGCGGGCAAAGGCCTT
CGATGGTGCCGCATTATTCAGTCCCTTTGTGGCGATTGATGATGCCGAGGCGCCGCTGCATTTTACCTTGAGTATCAACG
ATAACTTGGTGCAAGAGGGGCATATCGATTTAATGATCTACAAACCTCAGACCATTTTGTCCGAGTTGCAAGCGTTTATC
AGTCTCGATGAAGGCGATATTGTGATGACAGGCACGCCCAAAGGCGTGGGAGTGATTCCCGCTAAAAGTGTATTTAACGT
CACGCTGAGCCGGGGTCTGCAAGCGAGTGCTGAGCCTTTACTCGAATGGCAATGGCAAGTGTCTTGA

Upstream 100 bases:

>100_bases
AAAGTTAATTATTCTATTGAGAGTTTAGCGCTAGTTAAGGTTAACTTCTTGGTTTGATTATTTAAAAATAATCTCAACCG
TATCGTAAAAAGGATTAAAA

Downstream 100 bases:

>100_bases
GTCTTGAAAAGGTTGAAGTTCGCACGAACAACGTCAATTAATCGCGAAGTCATCAGTGCTGCTACGGCGAGTTATCCGTA
ATACCGCCGTAGTGTTAATT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKSVVLGEKRIVPTKIVCIGRNYVDHIHELGNDIPDDMVVFLKPNSAMSTVLLAEHQGEALHYETELCFMFQDGRFSSVA
IGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAIDDAEAPLHFTLSINDNLVQEGHIDLMIYKPQTILSELQAFI
SLDEGDIVMTGTPKGVGVIPAKSVFNVTLSRGLQASAEPLLEWQWQVS

Sequences:

>Translated_208_residues
MKSVVLGEKRIVPTKIVCIGRNYVDHIHELGNDIPDDMVVFLKPNSAMSTVLLAEHQGEALHYETELCFMFQDGRFSSVA
IGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAIDDAEAPLHFTLSINDNLVQEGHIDLMIYKPQTILSELQAFI
SLDEGDIVMTGTPKGVGVIPAKSVFNVTLSRGLQASAEPLLEWQWQVS
>Mature_208_residues
MKSVVLGEKRIVPTKIVCIGRNYVDHIHELGNDIPDDMVVFLKPNSAMSTVLLAEHQGEALHYETELCFMFQDGRFSSVA
IGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAIDDAEAPLHFTLSINDNLVQEGHIDLMIYKPQTILSELQAFI
SLDEGDIVMTGTPKGVGVIPAKSVFNVTLSRGLQASAEPLLEWQWQVS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=180, Percent_Identity=38.3333333333333, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI215422413, Length=180, Percent_Identity=38.3333333333333, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI13654274, Length=180, Percent_Identity=38.3333333333333, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI156231349, Length=204, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40786394, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1787428, Length=193, Percent_Identity=34.1968911917098, Blast_Score=114, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=202, Percent_Identity=34.1584158415842, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=214, Percent_Identity=33.1775700934579, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571789, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 22979; Mature: 22979

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVVLGEKRIVPTKIVCIGRNYVDHIHELGNDIPDDMVVFLKPNSAMSTVLLAEHQGEA
CCCEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCE
LHYETELCFMFQDGRFSSVAIGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAID
EEEEEEEEEEEECCCEEEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DAEAPLHFTLSINDNLVQEGHIDLMIYKPQTILSELQAFISLDEGDIVMTGTPKGVGVIP
CCCCCEEEEEEECCCEECCCCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCCCCEECC
AKSVFNVTLSRGLQASAEPLLEWQWQVS
CHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKSVVLGEKRIVPTKIVCIGRNYVDHIHELGNDIPDDMVVFLKPNSAMSTVLLAEHQGEA
CCCEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCE
LHYETELCFMFQDGRFSSVAIGLDLTKRDLQSKLKAKGLPWERAKAFDGAALFSPFVAID
EEEEEEEEEEEECCCEEEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DAEAPLHFTLSINDNLVQEGHIDLMIYKPQTILSELQAFISLDEGDIVMTGTPKGVGVIP
CCCCCEEEEEEECCCEECCCCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCCCCEECC
AKSVFNVTLSRGLQASAEPLLEWQWQVS
CHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]