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The map label for this gene is dxs [H]

Identifier: 160874500

GI number: 160874500

Start: 1655159

End: 1657027

Strand: Reverse

Name: dxs [H]

Synonym: Sbal195_1382

Alternate gene names: 160874500

Gene position: 1657027-1655159 (Counterclockwise)

Preceding gene: 160874501

Following gene: 160874499

Centisome position: 30.99

GC content: 50.94

Gene sequence:

>1869_bases
ATGAGTTTGGACATTTCTCAGTTTCCCGTGTTGGCACAGGCCAACACCCCCAATGAACTCCGCCAGCTTCCTCAGGCACT
TTTACCACAAGTAGCCGACGAACTGCGCGAGTTCCTTCTTAAGTCTGTTGGCATATCCAGCGGACATTTTGCCTCTGGGC
TCGGCACAGTGGAACTCACTGTTGCGCTGCACTATGTCTACAACACCCCTTTTGATCGGCTGATTTGGGATGTGGGCCAT
CAGGCTTATCCCCATAAAATTCTCACGGGTCGTCGTGACAAGATGCACACCATTAGACAAAAAGATGGCTTGCATCCTTT
CCCATGGCGTGAAGAAAGTGAATACGACACTTTCAGCGTTGGGCATTCAGGCACGTCTATCAGCGCCGCACTGGCGATGG
CGATTGCCGCAGAAAAAGAGCAAGCGGGTCGTAAAGTCGTTGCCGTGATCGGCGATGGCGCTATGACAGGCGGCATGGTG
TTTGAAGCCATGAACCACGCTGGCGACTTGCACAATGACATGCTCGTGGTGTTGAACGACAACGAAATGTCGATCTCTGA
AAATGTCGGCGCCCTCAATAACCATTTAGCACAACTGATGTCAGGCCGTTTCTACACTACGCTGCGCGAAGGCGGCAAGA
AAGTGTTGAAAGGCATGCCCGTCATCAAAGAAATGGCCAAACGCACTGAGGAACACCTCAAGGGCATGGTCGTTCCTGGC
ACGCTATTTGAGGAGTTAGGTTTCAACTATATCGGTCCTATCGACGGCCACGATGTTGATGCTCTGGTCGAGACCATGCG
TAATATGCGCAATCTGAAAGGTCCACAGGTGCTGCACATCATGACGAAGAAAGGTCGTGGTTATGAACCTGCTGAAAAAG
ATCCTATCGGTTGGCATGCGGTGCCTAAGTTTGACCCGTCGCTGTTTAAAAAGCCGGCTACCAAACCCGGTTTACCGACC
TTTTCCCAAGTCTTCGGTAAATGGTTATGCGACATCGCTGAGCAAGATGAGAAAGTATTAGCCATTACTCCTGCGATGCG
CGAAGGCTCGGGCATGGTGGAGTTTTCCCAGCGTTTCCCGAAACAATATTTCGATGCGGCGATTGCCGAGCAGCATGCAG
TGACTTTAGCCGCAGGTTTTGCCTGTGAAGGCTTTAAGCCTGTGGTGGCGATTTACTCGACCTTCCTGCAACGCGCCTAC
GATCAACTTATTCATGATGTGGCGCTACAGCAATTACCGGTATTGTTCGCTATCGATCGCGGCGGTATTGTCGGTGCCGA
TGGTCCAACTCACCAAGGTGCATTCGATTTAAGCTTTATGCGTTGCATCCCCAACATGGTGATCATGGCGCCGTCGGACG
AAAATGAATGTCGTCAAATGCTCTACACTGGCTATTGCTATGATGCGGGTCCAAGTGCAGTGCGTTATCCAAGGGGCAGC
GCCACGGGAGCGATGCAAGTCGAAGCGATGACGGCATTACCGATTGGTAAAGGCGTGATTAAACGTGTGGGCAAACGCAT
TGCCATTCTCAACTTTGGCACCTTGTTAGCATCAGCATTAACCGCAGCCGAAAGCTTAGATGCAACGGTTGTCGATATGC
GCTTTGTGAAACCACTTGATGTTGATTTGGTCAAAGAGATGGCGCAAACCCACGAAGTGCTCGTCACAGTGGAAGAAAAC
GCCATTATGGGCGGCGCTGGTGCTGGCGTGCTTGAGCAGCTTCAAAAGCTGCGAATGCCTAAAGCCGTGCTTCAAATTGG
TTTGCCAGATGAATTCATCAAACATGGCTCGCCAGAGGAAGTCACCCATGATTTGCAACTGGATGCCGAAGGTATACTGG
CGCAAATCAATGCTTATCTAGCACAATAA

Upstream 100 bases:

>100_bases
ATCAGCGCTGGCTAAATTGCCATACAATAGCCAGTTAATTGCAGACTTCGCCCGCTATATCATTGAGCGAAGAATATAAT
AAGAGTCGAAGTATCTCGCT

Downstream 100 bases:

>100_bases
ATGGCTCAATAGTTGGCGTAATAGGTAGAACTAGCTTATCTCGGTAAGGTGCTCAGTCTTACCAATACAAAGTCTTACCA
ATATAGATTCCGCCAATATT

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MSLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGH
QAYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSVGHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMV
FEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPG
TLFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHAVPKFDPSLFKKPATKPGLPT
FSQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLAAGFACEGFKPVVAIYSTFLQRAY
DQLIHDVALQQLPVLFAIDRGGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGS
ATGAMQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLDVDLVKEMAQTHEVLVTVEEN
AIMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEEVTHDLQLDAEGILAQINAYLAQ

Sequences:

>Translated_622_residues
MSLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGH
QAYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSVGHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMV
FEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPG
TLFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHAVPKFDPSLFKKPATKPGLPT
FSQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLAAGFACEGFKPVVAIYSTFLQRAY
DQLIHDVALQQLPVLFAIDRGGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGS
ATGAMQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLDVDLVKEMAQTHEVLVTVEEN
AIMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEEVTHDLQLDAEGILAQINAYLAQ
>Mature_621_residues
SLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQ
AYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSVGHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMVF
EAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPGT
LFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHAVPKFDPSLFKKPATKPGLPTF
SQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLAAGFACEGFKPVVAIYSTFLQRAYD
QLIHDVALQQLPVLFAIDRGGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGSA
TGAMQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLDVDLVKEMAQTHEVLVTVEENA
IMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEEVTHDLQLDAEGILAQINAYLAQ

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=521, Percent_Identity=22.6487523992322, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI4507521, Length=521, Percent_Identity=22.6487523992322, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI133778974, Length=621, Percent_Identity=24.3156199677939, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI225637463, Length=504, Percent_Identity=22.6190476190476, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI225637461, Length=504, Percent_Identity=22.6190476190476, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI225637459, Length=504, Percent_Identity=22.6190476190476, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786622, Length=621, Percent_Identity=71.9806763285024, Blast_Score=941, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=561, Percent_Identity=23.3511586452763, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24666278, Length=621, Percent_Identity=24.6376811594203, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45551847, Length=528, Percent_Identity=24.8106060606061, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45550715, Length=528, Percent_Identity=24.8106060606061, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645119, Length=528, Percent_Identity=24.8106060606061, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005477
- InterPro:   IPR011766
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 68020; Mature: 67889

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELT
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSV
EEEEHHHCCCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEC
GHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLND
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECC
NEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPG
CCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCC
TLFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCC
VPKFDPSLFKKPATKPGLPTFSQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFP
CCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCHHHHHHCC
KQYFDAAIAEQHAVTLAAGFACEGFKPVVAIYSTFLQRAYDQLIHDVALQQLPVLFAIDR
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGS
CCEECCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEECCCCCCEECCCCC
ATGAMQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLD
CCCCEEEEEEHHCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCEEHHHHCCCCC
VDLVKEMAQTHEVLVTVEENAIMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEE
HHHHHHHHHHCCEEEEEECCEEECCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCHHH
VTHDLQLDAEGILAQINAYLAQ
HHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELT
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
VALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSV
EEEEHHHCCCHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEC
GHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLND
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECC
NEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPG
CCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCC
TLFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCC
VPKFDPSLFKKPATKPGLPTFSQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFP
CCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCHHHHHHCC
KQYFDAAIAEQHAVTLAAGFACEGFKPVVAIYSTFLQRAYDQLIHDVALQQLPVLFAIDR
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGS
CCEECCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEECCCCCCEECCCCC
ATGAMQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLD
CCCCEEEEEEHHCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCEEHHHHCCCCC
VDLVKEMAQTHEVLVTVEENAIMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEE
HHHHHHHHHHCCEEEEEECCEEECCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCHHH
VTHDLQLDAEGILAQINAYLAQ
HHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA