Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 160874422

GI number: 160874422

Start: 1542188

End: 1542844

Strand: Reverse

Name: slyD [H]

Synonym: Sbal195_1303

Alternate gene names: 160874422

Gene position: 1542844-1542188 (Counterclockwise)

Preceding gene: 160874429

Following gene: 160874421

Centisome position: 28.85

GC content: 49.16

Gene sequence:

>657_bases
ATGAAGATCACTCAACACAGCGCGGTAACCATTCATTACCGTTTATCAGATCAAGAAGGCAGACTATTAGAAGACTCTTT
CGACTCTGAACCTATGCTATATCTACACGGCACTGAAAACTTGATCCCAGGTTTAGAAGCCGCATTAGATGGTAAAACCA
AAGGCGAAAAACTTGATGTCACTATTAGTGCCGAAGAAGCCTATGGCCCTTACCACGATGGCCTACGTCAAGCCGTGCCA
TTAGAAGCCTTTGGTGATATCGAAGATATCGTCCCAGGCATGCGCTTCATCGCCGAAACTGAAATGGGTCAACGCCCAGT
CCAAGTTATGGAAGTAAAAGACGATGTTGTTATAGTCGATGGCAACCATCCTTTAGCGGGTCAATCGCTCAACTTCAGCG
TCGAAATCGTTGACGTTCGCGAAGCCTCTGCCGAAGAAATTGCCCATGGCCACATTCATGCCCAAGGCGGTTGTGGAAGT
CATGGACATGATCACGACCATGGAGGTGGATGCTGTGGCGGTTCAGGTAAAGAAGAAGCAGGCGGCTGTTGTGGTGGTTC
AGATCACGATCATGGACATCACCATGAAGAGCATGAAGCCTGTGACACACCTAAAACAGGTTGTGACGGCAATGGCGGCT
GTGGTTGCCGCGGCTAG

Upstream 100 bases:

>100_bases
GAAAAAAAAGCTGTGCGATATCTAACATAAGCCACTTCAAATTATCGCCAGCACTAAAAAAGCACGTTATTATGCGCGCA
CATTCCGAACCGGAGGCGAT

Downstream 100 bases:

>100_bases
ATACTGATTGATGCCCAAGATGAGCTAGAAATAGTTTATCCCTAAGCGGTTGAACTGCCATAGTTTAACCTTTTAAGATG
CACGCCCTTAATTTAAGGTC

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKITQHSAVTIHYRLSDQEGRLLEDSFDSEPMLYLHGTENLIPGLEAALDGKTKGEKLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVMEVKDDVVIVDGNHPLAGQSLNFSVEIVDVREASAEEIAHGHIHAQGGCGS
HGHDHDHGGGCCGGSGKEEAGGCCGGSDHDHGHHHEEHEACDTPKTGCDGNGGCGCRG

Sequences:

>Translated_218_residues
MKITQHSAVTIHYRLSDQEGRLLEDSFDSEPMLYLHGTENLIPGLEAALDGKTKGEKLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVMEVKDDVVIVDGNHPLAGQSLNFSVEIVDVREASAEEIAHGHIHAQGGCGS
HGHDHDHGGGCCGGSGKEEAGGCCGGSDHDHGHHHEEHEACDTPKTGCDGNGGCGCRG
>Mature_218_residues
MKITQHSAVTIHYRLSDQEGRLLEDSFDSEPMLYLHGTENLIPGLEAALDGKTKGEKLDVTISAEEAYGPYHDGLRQAVP
LEAFGDIEDIVPGMRFIAETEMGQRPVQVMEVKDDVVIVDGNHPLAGQSLNFSVEIVDVREASAEEIAHGHIHAQGGCGS
HGHDHDHGGGCCGGSGKEEAGGCCGGSDHDHGHHHEEHEACDTPKTGCDGNGGCGCRG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=46.6216216216216, Blast_Score=137, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 23123; Mature: 23123

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITQHSAVTIHYRLSDQEGRLLEDSFDSEPMLYLHGTENLIPGLEAALDGKTKGEKLDV
CCCCCCCEEEEEEEECCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCEEEE
TISAEEAYGPYHDGLRQAVPLEAFGDIEDIVPGMRFIAETEMGQRPVQVMEVKDDVVIVD
EEECHHHCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQSLNFSVEIVDVREASAEEIAHGHIHAQGGCGSHGHDHDHGGGCCGGSGKEEA
CCCCCCCCCCCEEEEEEECCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GGCCGGSDHDHGHHHEEHEACDTPKTGCDGNGGCGCRG
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITQHSAVTIHYRLSDQEGRLLEDSFDSEPMLYLHGTENLIPGLEAALDGKTKGEKLDV
CCCCCCCEEEEEEEECCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCEEEE
TISAEEAYGPYHDGLRQAVPLEAFGDIEDIVPGMRFIAETEMGQRPVQVMEVKDDVVIVD
EEECHHHCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQSLNFSVEIVDVREASAEEIAHGHIHAQGGCGSHGHDHDHGGGCCGGSGKEEA
CCCCCCCCCCCEEEEEEECCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GGCCGGSDHDHGHHHEEHEACDTPKTGCDGNGGCGCRG
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]