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The map label for this gene is purE [H]

Identifier: 160874257

GI number: 160874257

Start: 1347459

End: 1347950

Strand: Reverse

Name: purE [H]

Synonym: Sbal195_1137

Alternate gene names: 160874257

Gene position: 1347950-1347459 (Counterclockwise)

Preceding gene: 160874258

Following gene: 160874256

Centisome position: 25.21

GC content: 49.59

Gene sequence:

>492_bases
ATGCAAGCCCTTGTTGCTGTTGTTATGGGTTCTAAAAGTGATTGGCCCACGATGGAAGCCGCCGCTGAGATAATGGATAA
ACTGCAAGTGCCTTATCATGTTGAAGTGGTTTCCGCCCATAGAACGCCAGATAAACTCATGGAGTTTGCAGCCTCTGCCG
CCGATCGTGGTTTTAAAATCATCATTGGTGGCGCCGGTGGTGCAGCGCACTTACCCGGTATGATTGCCTCTAAAACTCGC
TTACCCGTATTAGGTGTCCCAGTCCAAAGTAAAGCCCTGTCAGGTATGGATAGCTTATTGTCTATCGTTCAAATGCCAAA
AGGCATCGCCGTTGGCACTTTAGCCATAGGCACAGCGGGCGCATTCAATGCGGGATTATTGGCCTGCCAAATCCTTGCGA
ATAACGATGCTGAATTAGCGGCTCGTGTTGACGCTTTCAGAGAAGAACAGACCCGTGCGGTACTGGACAATCCAGATCCG
AGGGAAGTTTAA

Upstream 100 bases:

>100_bases
CATGATGCTTGCTACCGGTGACGGCTAGACAAGCATCAACTGTACCTAGACCTGAAACAAGGTCAAAATATAATTAAAAT
TAGTGAGTTAAGGAGTTATC

Downstream 100 bases:

>100_bases
TGACCCAGACAAACACTAAACCTAAGGTTTGGGTATTAGGTAATGGTCAGCTGGGCGCCATGTTAACCCACGCTGGCGAG
CCATTAGCGATTGAAGTTAA

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAASAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARVDAFREEQTRAVLDNPDP
REV

Sequences:

>Translated_163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAASAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARVDAFREEQTRAVLDNPDP
REV
>Mature_163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAASAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARVDAFREEQTRAVLDNPDP
REV

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=159, Percent_Identity=71.0691823899371, Blast_Score=196, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324702, Length=155, Percent_Identity=49.0322580645161, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16990; Mature: 16990

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAASAADRGFKI
CCHHEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
IIGGAGGAAHLPGMIASKTRLPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFNAGLLACQILANNDAELAARVDAFREEQTRAVLDNPDPREV
CCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAASAADRGFKI
CCHHEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
IIGGAGGAAHLPGMIASKTRLPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFNAGLLACQILANNDAELAARVDAFREEQTRAVLDNPDPREV
CCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA