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The map label for this gene is surA [H]

Identifier: 160874201

GI number: 160874201

Start: 1278428

End: 1279732

Strand: Reverse

Name: surA [H]

Synonym: Sbal195_1081

Alternate gene names: 160874201

Gene position: 1279732-1278428 (Counterclockwise)

Preceding gene: 160874202

Following gene: 160874200

Centisome position: 23.93

GC content: 45.98

Gene sequence:

>1305_bases
ATGAAACCCAGTAAACATCTGATTTTTGCTTTATTTGCACTCGCTATCAGCCAACCTACATTGGCCGCACCTCAGCCGCT
CGACCGCGTTGCGGTCCAAATTAACGACGGCATAGTGCTCGAAAGTGAAATCACTAACATGATTGACACTGTTAAAGCCA
ATGCCAAAACGGCAAACCAATCGTTACCTTCTGACAGTGCCCTGCGTACTCAGGTGATTGAACGTTTGATCTTGACCCGT
TTACAACTGCAAATGGCAGATCGTATTGGCCTGCATATTGGTGACTTACAATTAGACCAAGCGATTGAAAACATCGCGCG
CGAACAAAAAATGTCTGTGGCGCAGATGCAACAGAAAATTGAAAGCGAAGGGTTAAGCTTCAGCCAATACCGCGAGCAGT
TGCGCGAAGAAATCACCCTAGGTGAAATTCAGCGTATTCAAGTACAACGTCGTATTCAAGTGTCACCACAGGAAATTACT
AGCCTAGTCAAACTCATCCAAGAACAAGGGATGAAAGATGTGGAATACCAAATTGGCCACATCCTGATTGACGTGCCAAA
TAATCCTACCAGTGAACAACTGGAATCCTCGAGCAAACGTGCCAATATCGTTTTGGAGCGTTTAAAGAGTGGTGAAGATT
TCCGTCGTACCGCTATCGCATCTTCTTCGGGCCCTAAAGCACTCGAAGGCGGTATTTGGGACTACATGAACATCAACGAA
ATGCCAACCCTGTTCGCCGAAGTGATCAACGGTGCGAAAACGGGTGACATTATCGGCCCTATTAAGAGTGGTGCTGGCTT
CCATATTATTAAAATCATGGATGCTCGCGGACTACAAACCAAAGAAATTGAAGAAGTCAGAGCGCGCCACATTTTGCTCA
AGCCATCGCCAATTTTGTCAGAAGATCGTGCTAAAGCCATGCTTGAGCAATTTCTGAAGCAAATTCGCTCAGGTGAAGCT
AAATTTGAAGACCTAGCGCGTCAATATTCTGAAGATCCAGGTTCAGCCACTAAAGGCGGCGAATTAGGTTGGGCAGAGCC
AAGCATTTACGTGCCAGAGTTCGCTCAAACCCTTAACAGTTTAAAAACTGACCAGATCAGTGAGCCATTCCGTACTACTC
ACGGTTGGCACATTACCCAGTTAGAAGAACGCAGAAAAACCGATGCCACGGATCAGTTCAACAGTAACCGTGCGCACCAG
TTGATCTTCCGTCGCAAATTTAACGAAGAACTGCAAAACTGGCTAGACGAAATGCGTTCAGACGCATACATTGAAATCTT
CCAGCCAGAGACCAATCGAGGTTAA

Upstream 100 bases:

>100_bases
AATTACATTAGGGCAACTCGCTGTAATTTCGATATAAATGGTAAAGTTATTTCAATTAAGCCGTCGAACCTGACCTTAGA
ACGTGCCAAGGATTTTGTGG

Downstream 100 bases:

>100_bases
TTCTAATTGAGCACTAAACGTATTGCCATTACCCCAGGTGAACCCGCAGGTATTGGCCCCGATTTAGTCGTACAACTCGC
TCAGCAGGCTTGGCCTGCTG

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKPSKHLIFALFALAISQPTLAAPQPLDRVAVQINDGIVLESEITNMIDTVKANAKTANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMSVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
SLVKLIQEQGMKDVEYQIGHILIDVPNNPTSEQLESSSKRANIVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKTGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLKTDQISEPFRTTHGWHITQLEERRKTDATDQFNSNRAHQ
LIFRRKFNEELQNWLDEMRSDAYIEIFQPETNRG

Sequences:

>Translated_434_residues
MKPSKHLIFALFALAISQPTLAAPQPLDRVAVQINDGIVLESEITNMIDTVKANAKTANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMSVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
SLVKLIQEQGMKDVEYQIGHILIDVPNNPTSEQLESSSKRANIVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKTGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLKTDQISEPFRTTHGWHITQLEERRKTDATDQFNSNRAHQ
LIFRRKFNEELQNWLDEMRSDAYIEIFQPETNRG
>Mature_434_residues
MKPSKHLIFALFALAISQPTLAAPQPLDRVAVQINDGIVLESEITNMIDTVKANAKTANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMSVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
SLVKLIQEQGMKDVEYQIGHILIDVPNNPTSEQLESSSKRANIVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKTGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLKTDQISEPFRTTHGWHITQLEERRKTDATDQFNSNRAHQ
LIFRRKFNEELQNWLDEMRSDAYIEIFQPETNRG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=429, Percent_Identity=42.4242424242424, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49093; Mature: 49093

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSKHLIFALFALAISQPTLAAPQPLDRVAVQINDGIVLESEITNMIDTVKANAKTANQ
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHCCCHHHCC
SLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMSVAQMQQKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEITSLVKLIQEQGMKDVEYQIGH
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECE
ILIDVPNNPTSEQLESSSKRANIVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCH
MPTLFAEVINGAKTGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCC
EDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LKTDQISEPFRTTHGWHITQLEERRKTDATDQFNSNRAHQLIFRRKFNEELQNWLDEMRS
HHHHHCCCCHHHCCCEEEHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DAYIEIFQPETNRG
CCEEEEECCCCCCC
>Mature Secondary Structure
MKPSKHLIFALFALAISQPTLAAPQPLDRVAVQINDGIVLESEITNMIDTVKANAKTANQ
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHCCCHHHCC
SLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMSVAQMQQKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEITSLVKLIQEQGMKDVEYQIGH
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECE
ILIDVPNNPTSEQLESSSKRANIVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCH
MPTLFAEVINGAKTGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCC
EDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LKTDQISEPFRTTHGWHITQLEERRKTDATDQFNSNRAHQLIFRRKFNEELQNWLDEMRS
HHHHHCCCCHHHCCCEEEHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DAYIEIFQPETNRG
CCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]