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The map label for this gene is minD [H]

Identifier: 159899939

GI number: 159899939

Start: 4312347

End: 4313147

Strand: Direct

Name: minD [H]

Synonym: Haur_3422

Alternate gene names: 159899939

Gene position: 4312347-4313147 (Clockwise)

Preceding gene: 159899938

Following gene: 159899940

Centisome position: 67.95

GC content: 48.81

Gene sequence:

>801_bases
ATGGCACAAGTAATCACAATCACCTCTGGTAAAGGGGGGGTTGGCAAAACCACCACCACCGCCAATCTCGCCACATCGTT
AGCAATGCAAGGCCAACGGGTTGTTGCAATTGATGCTGATATCGGTTTGCGCAATCTCGATGTGGTGATGGGCCTCGAAA
ATCGGATCGTCTATGATTTGGTCGATGTGGTTGAAGGCCGCTGTCGCACACGTCAAGCGCTCATTAAAGATAAGCGCTTT
CCTGATAATTTGTTCTTGTTGCCAGCAGCCCAAACCCGCGATAAAGATGCGGTAACGCCTGACGATATGATCGCCCTTTG
CAACGAGTTACGCCGCGAATTTGATTTTATTCTGATCGACTCGCCCGCTGGGATCGAGGGTGGCTTTAAAAATGCAATTG
CACCCGCCGACCACATTTTGATCGTCACAACACCTGAAATGTCTGCTGTGCGCGATGCCGACCGGATTGTAGGGTTGGTC
GAAGCGTATGAAAAAAGCAATCCAAAGCTCATTATTAACCGAATTAAAGCGCGGATGGTTGCTCGCGGCGACATGATGGA
TACGCCCGATGTGGTAGAAATTTTGGCAATCGACCTGGTTGGAATTGTGCCAGACGATGAAAGCATTGTGGTTTCAACCA
ACCGTGGTGAAGTTGCGGTGCTTGATCGTGAATCGATGGCAGGTAAGGCCTATAATAATATCGCCAATCGTTTACTTGGC
CACGATATTCCCTTCCTTGTGCTTGATGAAAAACAAGGCTTATGGGCACAATTGGTCAATATGTTTCGTACCCGCCGCTA
A

Upstream 100 bases:

>100_bases
ATCGCCCAACTGGCCCTGAACAAGCCAGCCTTGATGGCGACAACATTGTAGTAGTACCATGGGATGCCCCACGCCGCTAG
TGGGTCTTTGAGGATCATGT

Downstream 100 bases:

>100_bases
AATGGCGCGGTTGAGCCATCTTTATCTTCCACATGGAGCGGATGTATGGGTCTTTTAGATAATCTTTTTGGTCGCAAGCA
ACAGAACAGTTCGTCGGTTG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MAQVITITSGKGGVGKTTTTANLATSLAMQGQRVVAIDADIGLRNLDVVMGLENRIVYDLVDVVEGRCRTRQALIKDKRF
PDNLFLLPAAQTRDKDAVTPDDMIALCNELRREFDFILIDSPAGIEGGFKNAIAPADHILIVTTPEMSAVRDADRIVGLV
EAYEKSNPKLIINRIKARMVARGDMMDTPDVVEILAIDLVGIVPDDESIVVSTNRGEVAVLDRESMAGKAYNNIANRLLG
HDIPFLVLDEKQGLWAQLVNMFRTRR

Sequences:

>Translated_266_residues
MAQVITITSGKGGVGKTTTTANLATSLAMQGQRVVAIDADIGLRNLDVVMGLENRIVYDLVDVVEGRCRTRQALIKDKRF
PDNLFLLPAAQTRDKDAVTPDDMIALCNELRREFDFILIDSPAGIEGGFKNAIAPADHILIVTTPEMSAVRDADRIVGLV
EAYEKSNPKLIINRIKARMVARGDMMDTPDVVEILAIDLVGIVPDDESIVVSTNRGEVAVLDRESMAGKAYNNIANRLLG
HDIPFLVLDEKQGLWAQLVNMFRTRR
>Mature_265_residues
AQVITITSGKGGVGKTTTTANLATSLAMQGQRVVAIDADIGLRNLDVVMGLENRIVYDLVDVVEGRCRTRQALIKDKRFP
DNLFLLPAAQTRDKDAVTPDDMIALCNELRREFDFILIDSPAGIEGGFKNAIAPADHILIVTTPEMSAVRDADRIVGLVE
AYEKSNPKLIINRIKARMVARGDMMDTPDVVEILAIDLVGIVPDDESIVVSTNRGEVAVLDRESMAGKAYNNIANRLLGH
DIPFLVLDEKQGLWAQLVNMFRTRR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=268, Percent_Identity=48.134328358209, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29211; Mature: 29080

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVITITSGKGGVGKTTTTANLATSLAMQGQRVVAIDADIGLRNLDVVMGLENRIVYDL
CCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCHHHHHH
VDVVEGRCRTRQALIKDKRFPDNLFLLPAAQTRDKDAVTPDDMIALCNELRREFDFILID
HHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEE
SPAGIEGGFKNAIAPADHILIVTTPEMSAVRDADRIVGLVEAYEKSNPKLIINRIKARMV
CCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
ARGDMMDTPDVVEILAIDLVGIVPDDESIVVSTNRGEVAVLDRESMAGKAYNNIANRLLG
HCCCCCCCHHHHHHHHHHHEEECCCCCCEEEECCCCCEEEEECHHHCCHHHHHHHHHHHC
HDIPFLVLDEKQGLWAQLVNMFRTRR
CCCCEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AQVITITSGKGGVGKTTTTANLATSLAMQGQRVVAIDADIGLRNLDVVMGLENRIVYDL
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCHHHHHH
VDVVEGRCRTRQALIKDKRFPDNLFLLPAAQTRDKDAVTPDDMIALCNELRREFDFILID
HHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEE
SPAGIEGGFKNAIAPADHILIVTTPEMSAVRDADRIVGLVEAYEKSNPKLIINRIKARMV
CCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
ARGDMMDTPDVVEILAIDLVGIVPDDESIVVSTNRGEVAVLDRESMAGKAYNNIANRLLG
HCCCCCCCHHHHHHHHHHHEEECCCCCCEEEECCCCCEEEEECHHHCCHHHHHHHHHHHC
HDIPFLVLDEKQGLWAQLVNMFRTRR
CCCCEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]