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The map label for this gene is walR [H]

Identifier: 159899908

GI number: 159899908

Start: 4275152

End: 4275835

Strand: Direct

Name: walR [H]

Synonym: Haur_3391

Alternate gene names: 159899908

Gene position: 4275152-4275835 (Clockwise)

Preceding gene: 159899907

Following gene: 159899909

Centisome position: 67.36

GC content: 49.71

Gene sequence:

>684_bases
ATGAAGATTTTAGTCGTTGATGATGATGCTGAATTGCGCGGATTAATTGGTTTTGCCTTGAGCCAAGCAGGCTATGCGGT
AGTGCAAGCAGCTGATGGTACGCAAGCATTAACTCAATTCGCTGCTGAACAACCTGAATTGGTGATTCTCGATGTAAATA
TGCCTGGTTTGGATGGATTTGAAGTTTGTCGGCGCATCCGTGCTCAGTCGATAGTACCGGTCATGCTCCTGACTGTGCGC
AACAGCGAAGATGATCTGATTCGCGGCTTGGATGGTGGCGCTGATGATTATCTCAACAAGCCATTTAGCCCGCGCACTCT
GACGGCGCGAGTGCGTGCGCTGTTGCGACGTGTCGGCGGCGAACGACCAACACCGTTGCAACAAGGCGATTTAGTGTTGG
ATACCGATCGCCAAAGTGTTAGTCGCGAAGGCTTGGGCTTTGTCGCCTTGACTAATCGTGAATTTCGTTTGCTGCAATAT
TTATTGGCCAATGCAGGGCGGGTCGTCAGCAATGAGCAAGTCACAATCCACGTTTGGGGCCATCATGGAATTGGCGATCG
CACCTTGTTGAAACAATTGGTGCATCGTTTACGCCAAAAAATCGAGCCAAATCCCACCGAACCCCAATATTTAGTTACGA
TCCCTAGTGTTGGCTATATGTTGCAGCCCAACGGCACAAACTAG

Upstream 100 bases:

>100_bases
TGGATTGTTCAATCAATTATTGAGCGTCACAATGGCCGAATTCATGTGCCAGCCCGCAGCCTTGGCACGCGGATTGTGAT
TGAATTACCCAGAGGAACTG

Downstream 100 bases:

>100_bases
AGCTGCATCAAAACCTAGCCAACCAACGTACAAGCTGCGACTATTTGGGAGAGAACGATGAAACGTAGCCAGACATTGCT
GTACGCAGCTGTTGCACTTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGFEVCRRIRAQSIVPVMLLTVR
NSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGGERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQY
LLANAGRVVSNEQVTIHVWGHHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN

Sequences:

>Translated_227_residues
MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGFEVCRRIRAQSIVPVMLLTVR
NSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGGERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQY
LLANAGRVVSNEQVTIHVWGHHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN
>Mature_227_residues
MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGFEVCRRIRAQSIVPVMLLTVR
NSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGGERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQY
LLANAGRVVSNEQVTIHVWGHHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=38.8127853881278, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=36.5296803652968, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=36.1702127659575, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786599, Length=209, Percent_Identity=36.8421052631579, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.0869565217391, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.0877192982456, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=209, Percent_Identity=38.2775119617225, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=36.6812227074236, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=33.1858407079646, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.5964125560538, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.9649122807018, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=30.6382978723404, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=32.6732673267327, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=36.5217391304348, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=104, Percent_Identity=36.5384615384615, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25087; Mature: 25087

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGF
CEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCHH
EVCRRIRAQSIVPVMLLTVRNSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGG
HHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCC
ERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQYLLANAGRVVSNEQVTIHVWG
CCCCCCCCCCEEEECCHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEECCCEEEEEEEC
HHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCC
>Mature Secondary Structure
MKILVVDDDAELRGLIGFALSQAGYAVVQAADGTQALTQFAAEQPELVILDVNMPGLDGF
CEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCHH
EVCRRIRAQSIVPVMLLTVRNSEDDLIRGLDGGADDYLNKPFSPRTLTARVRALLRRVGG
HHHHHHHHHCCCEEEEEEEECCCHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCC
ERPTPLQQGDLVLDTDRQSVSREGLGFVALTNREFRLLQYLLANAGRVVSNEQVTIHVWG
CCCCCCCCCCEEEECCHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEECCCEEEEEEEC
HHGIGDRTLLKQLVHRLRQKIEPNPTEPQYLVTIPSVGYMLQPNGTN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA