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The map label for this gene is rsbRA [H]

Identifier: 159899680

GI number: 159899680

Start: 3991393

End: 3993309

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_3162

Alternate gene names: 159899680

Gene position: 3991393-3993309 (Clockwise)

Preceding gene: 159899679

Following gene: 159899681

Centisome position: 62.89

GC content: 47.63

Gene sequence:

>1917_bases
ATGCGTGCATTCTTTACTCCAGCCACATGGCTGATGAAACGCCTAACCTATCCCCAAAAATTTGGGTTATTGAGCTTGGT
TTTCGCCATTCCATTAACCTTTTTGCTGAGTGCCCAATTAACTGAAATTCAACGCCAAATTAATTTCACGCGGAGCGAAC
TAACTGGCACAACCTACCTGCAACCGCTACGTGAAATTTTGCAAGATATTATCGAGCAACAATTAATCGCCGAGCAATAT
CTTGGTGGCGATCAAGCATTTTTAACCCCACTTTTGCTTAAAAACGAAGAGCTTGCCCAACATCTTGAGACATTTAAAGC
CTTCGATTTACAATATCAGGATCGTTACGATACCCAAACGCAAGTCACAATTCTTTTTAATGAATGGGAGCGGCTGCAAG
CTCAATTAACCTTACGCAGTGTTCCCGATAGTAATGCCGCCCACGATCGGCTAATTCAGGCGGTTCGCGCATGTATGCAG
CGTATCGGTGATCAATCAGGCTTAATTCTCGACCCAAACATTGATAGCTATTATTTAATGAATGCCTTGATTGAAACCTT
GCCAGCCCATCAAGCTGCTACTGCGCGGGTTGCTGGCGCTGGTGGTAATGCAATCACTCGTGGCACGGTCAGCAGCGAAG
AAAAAAACACGCTGACGGTCGTCAATAGCCAACTCCAAGAAACCAATACCAAAATTAACTATAGCTTAGGCGTAGTATTT
AGCAATAATGAAAGCTTACGTCCATTACTAGAAAGTGCAGTCCGCACCTTTATTCAGGCGACTGAAGAATTAAGCTTCCA
AATTATTTTGCAAGTGATTCGCGTTGAAACTCCAACGATTGATCCAAGCATTTTTCGCCAAGAAACTGAGCGCACCCTCA
ATGCAAGCTTTAGCCTATGGGATCAAACATCAATTCAGCTTGATAATGTGCTCAACCAGCGTATTGGCCAAGCTCAAAAT
CGTCGAATCTTTTTCATCAGCCTGATTACGATTCTTGTCTTAGTGGCAGTATATCTCTTCCTTGGCTTCTATCGCGCAGT
AATGGATACAGTTCGCGCTTTTCAACAGGCAGCTGGCAGTATGCTAAGCTCAAATACCTTGAGCAATGTAGCAATTGATA
CCCGCGATGAATTAGGCCAAGTTGCAACGTCGTTTAACTCAATCGCCAGCGCCATGGTCGAATCGAGCAGCCAACGCCAA
GCCATCGTTGATCACGCTGCCGAAGCAATTATTACCTACGATCAACAAGGCATTATTCGCTCAGCCAATCGCGCTGCCGA
ACGCATTTTGGGCCGCAACGTCGATCAACTAAATATTGCCGAAGTGCTGGGAGTCGAATTAGCCAACATCCAACAACAAA
CCACGACCTATGAGTTTGATGTACGCTTACCAACCAATGAGATTCAACCGGTTGAAATGGTGTTGGGCACAATGCAGCTC
GGCGAGCAGCAACTCTGGATCGCCTTCCTGCGTGATATTCGCATCCGCCGCCGCACAGAGCAAGAACGCAATCGGCTGCA
AGATGAGATTATTCGTGGCCATGCCGCCGTGCTCGCTCGCCTGAGTGCTCCATTAATTCCGCTCAGCGATAATGTGGTAG
TCATGCCGTTGGTCGGGGCGCTTGATGGTGAACGTTTACAGCAAATTACCAATAATTTGCTCGAAGGATTGTCGAACCAA
CGGGCGCGGGTGGCCTTGCTCGATATGACGGGCGTACCAAATGTTGATCGTGAAGTTGCCAGCCGTTTGTTACGTGCCGC
CCAAGGCATTCGCTTACTTGGCGCAGACCTCATTTTGACCGGAATTCAGCCCGATGTGGCCCAAGCATTAATCAGCGTGG
GCGGCGATCTCAGCGACCTCCAGACCTACCCCACCTTGCAACAAGGTATTCGGATGGTGCTGCGCAACCTAGCGTAA

Upstream 100 bases:

>100_bases
AAGCCCAGCCAAATAGGGGATGCAAAGTCCTACTGCACAAAAATATCCAGATATGCTATGATAAGGTGCAACCACACCTC
AGCCATTAGGTATCCGAACC

Downstream 100 bases:

>100_bases
CCCCAGCCATCCAATCCACGTACCAGCAACGAACCTATCTTAACGCCTCACAAAGCGCTACAATAGAGCTTGACAGTTTA
AGGAGAATAAGCTTATGCAA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MRAFFTPATWLMKRLTYPQKFGLLSLVFAIPLTFLLSAQLTEIQRQINFTRSELTGTTYLQPLREILQDIIEQQLIAEQY
LGGDQAFLTPLLLKNEELAQHLETFKAFDLQYQDRYDTQTQVTILFNEWERLQAQLTLRSVPDSNAAHDRLIQAVRACMQ
RIGDQSGLILDPNIDSYYLMNALIETLPAHQAATARVAGAGGNAITRGTVSSEEKNTLTVVNSQLQETNTKINYSLGVVF
SNNESLRPLLESAVRTFIQATEELSFQIILQVIRVETPTIDPSIFRQETERTLNASFSLWDQTSIQLDNVLNQRIGQAQN
RRIFFISLITILVLVAVYLFLGFYRAVMDTVRAFQQAAGSMLSSNTLSNVAIDTRDELGQVATSFNSIASAMVESSSQRQ
AIVDHAAEAIITYDQQGIIRSANRAAERILGRNVDQLNIAEVLGVELANIQQQTTTYEFDVRLPTNEIQPVEMVLGTMQL
GEQQLWIAFLRDIRIRRRTEQERNRLQDEIIRGHAAVLARLSAPLIPLSDNVVVMPLVGALDGERLQQITNNLLEGLSNQ
RARVALLDMTGVPNVDREVASRLLRAAQGIRLLGADLILTGIQPDVAQALISVGGDLSDLQTYPTLQQGIRMVLRNLA

Sequences:

>Translated_638_residues
MRAFFTPATWLMKRLTYPQKFGLLSLVFAIPLTFLLSAQLTEIQRQINFTRSELTGTTYLQPLREILQDIIEQQLIAEQY
LGGDQAFLTPLLLKNEELAQHLETFKAFDLQYQDRYDTQTQVTILFNEWERLQAQLTLRSVPDSNAAHDRLIQAVRACMQ
RIGDQSGLILDPNIDSYYLMNALIETLPAHQAATARVAGAGGNAITRGTVSSEEKNTLTVVNSQLQETNTKINYSLGVVF
SNNESLRPLLESAVRTFIQATEELSFQIILQVIRVETPTIDPSIFRQETERTLNASFSLWDQTSIQLDNVLNQRIGQAQN
RRIFFISLITILVLVAVYLFLGFYRAVMDTVRAFQQAAGSMLSSNTLSNVAIDTRDELGQVATSFNSIASAMVESSSQRQ
AIVDHAAEAIITYDQQGIIRSANRAAERILGRNVDQLNIAEVLGVELANIQQQTTTYEFDVRLPTNEIQPVEMVLGTMQL
GEQQLWIAFLRDIRIRRRTEQERNRLQDEIIRGHAAVLARLSAPLIPLSDNVVVMPLVGALDGERLQQITNNLLEGLSNQ
RARVALLDMTGVPNVDREVASRLLRAAQGIRLLGADLILTGIQPDVAQALISVGGDLSDLQTYPTLQQGIRMVLRNLA
>Mature_638_residues
MRAFFTPATWLMKRLTYPQKFGLLSLVFAIPLTFLLSAQLTEIQRQINFTRSELTGTTYLQPLREILQDIIEQQLIAEQY
LGGDQAFLTPLLLKNEELAQHLETFKAFDLQYQDRYDTQTQVTILFNEWERLQAQLTLRSVPDSNAAHDRLIQAVRACMQ
RIGDQSGLILDPNIDSYYLMNALIETLPAHQAATARVAGAGGNAITRGTVSSEEKNTLTVVNSQLQETNTKINYSLGVVF
SNNESLRPLLESAVRTFIQATEELSFQIILQVIRVETPTIDPSIFRQETERTLNASFSLWDQTSIQLDNVLNQRIGQAQN
RRIFFISLITILVLVAVYLFLGFYRAVMDTVRAFQQAAGSMLSSNTLSNVAIDTRDELGQVATSFNSIASAMVESSSQRQ
AIVDHAAEAIITYDQQGIIRSANRAAERILGRNVDQLNIAEVLGVELANIQQQTTTYEFDVRLPTNEIQPVEMVLGTMQL
GEQQLWIAFLRDIRIRRRTEQERNRLQDEIIRGHAAVLARLSAPLIPLSDNVVVMPLVGALDGERLQQITNNLLEGLSNQ
RARVALLDMTGVPNVDREVASRLLRAAQGIRLLGADLILTGIQPDVAQALISVGGDLSDLQTYPTLQQGIRMVLRNLA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 71377; Mature: 71377

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50112 PAS ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFFTPATWLMKRLTYPQKFGLLSLVFAIPLTFLLSAQLTEIQRQINFTRSELTGTTYL
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QPLREILQDIIEQQLIAEQYLGGDQAFLTPLLLKNEELAQHLETFKAFDLQYQDRYDTQT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCE
QVTILFNEWERLQAQLTLRSVPDSNAAHDRLIQAVRACMQRIGDQSGLILDPNIDSYYLM
EEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHH
NALIETLPAHQAATARVAGAGGNAITRGTVSSEEKNTLTVVNSQLQETNTKINYSLGVVF
HHHHHHHCCCHHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEE
SNNESLRPLLESAVRTFIQATEELSFQIILQVIRVETPTIDPSIFRQETERTLNASFSLW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEC
DQTSIQLDNVLNQRIGQAQNRRIFFISLITILVLVAVYLFLGFYRAVMDTVRAFQQAAGS
CCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLSSNTLSNVAIDTRDELGQVATSFNSIASAMVESSSQRQAIVDHAAEAIITYDQQGIIR
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHH
SANRAAERILGRNVDQLNIAEVLGVELANIQQQTTTYEFDVRLPTNEIQPVEMVLGTMQL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHH
GEQQLWIAFLRDIRIRRRTEQERNRLQDEIIRGHAAVLARLSAPLIPLSDNVVVMPLVGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEHHC
LDGERLQQITNNLLEGLSNQRARVALLDMTGVPNVDREVASRLLRAAQGIRLLGADLILT
CCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHCCCHHHEE
GIQPDVAQALISVGGDLSDLQTYPTLQQGIRMVLRNLA
CCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAFFTPATWLMKRLTYPQKFGLLSLVFAIPLTFLLSAQLTEIQRQINFTRSELTGTTYL
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QPLREILQDIIEQQLIAEQYLGGDQAFLTPLLLKNEELAQHLETFKAFDLQYQDRYDTQT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCE
QVTILFNEWERLQAQLTLRSVPDSNAAHDRLIQAVRACMQRIGDQSGLILDPNIDSYYLM
EEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHH
NALIETLPAHQAATARVAGAGGNAITRGTVSSEEKNTLTVVNSQLQETNTKINYSLGVVF
HHHHHHHCCCHHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEE
SNNESLRPLLESAVRTFIQATEELSFQIILQVIRVETPTIDPSIFRQETERTLNASFSLW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEC
DQTSIQLDNVLNQRIGQAQNRRIFFISLITILVLVAVYLFLGFYRAVMDTVRAFQQAAGS
CCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLSSNTLSNVAIDTRDELGQVATSFNSIASAMVESSSQRQAIVDHAAEAIITYDQQGIIR
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHH
SANRAAERILGRNVDQLNIAEVLGVELANIQQQTTTYEFDVRLPTNEIQPVEMVLGTMQL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHH
GEQQLWIAFLRDIRIRRRTEQERNRLQDEIIRGHAAVLARLSAPLIPLSDNVVVMPLVGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEEHHC
LDGERLQQITNNLLEGLSNQRARVALLDMTGVPNVDREVASRLLRAAQGIRLLGADLILT
CCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHCCCHHHEE
GIQPDVAQALISVGGDLSDLQTYPTLQQGIRMVLRNLA
CCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]