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The map label for this gene is baeS [H]

Identifier: 159899581

GI number: 159899581

Start: 3868307

End: 3869683

Strand: Direct

Name: baeS [H]

Synonym: Haur_3062

Alternate gene names: 159899581

Gene position: 3868307-3869683 (Clockwise)

Preceding gene: 159899580

Following gene: 159899582

Centisome position: 60.95

GC content: 52.0

Gene sequence:

>1377_bases
ATGAAACTGCAACGAAAATTATTATTAACCCACATCGCAGTTGCCCTCGTTGCAATTTTGCTGATTACGGCGGTGGCCAA
CTTCACCGTCAATCGCTATTTTAGCGATCTTGCGGCCAAACAGGCCAAACAAGCAGCCCAAGAGTTTGCGCCAACCTTGG
CAACCTGCTACCAAATTATTGGCAGCTGGGATTTTAATGGCCAGCGTTGTATGCAGCTTGGGCCACGACCGTTCATGCCG
CCGCAATTTCGCCATGTCGTGGTAGTTGATACCGCTGGTGAGATTGTTTTTGATAGCCGTGGACGCGGCCAAATTAATAA
ACCAACCAACACCATTACCCAACGCGATATTGAACGTGGCGAATCAATTAATGCTGAAGATGGCACGGTGATTGGCACGG
TGATTGTGCGACCCAATCAAGGCCAATTTGGCGCAGATGAAGATTATTTTTTGAGTATGGTGCGGCGTAATATTTGGTTG
GCCGGAGCAATTACCGCCCTCTTAGCCTTGGCTATTGGCATCGGCCTGGCGCGAACCTTGGCCGCGCCGTTGCGCAGCCT
GACTGCCGCCGTGCATCAACTGGCTCAGGGCGAACGTTCAGTTCAAGTTGACGATTCGGGCAACGATGAAATTGCCGAAT
TAAGCCAAGCCTTTAACACCATGAGCAGCGAACTGCATCGCTCTGAGCAAGTGCGCCGCCAGATGGTTGCCGATATTGCT
CACGAATTGCGTACCCCTTTGAGCGTGCTGCAAATTGAGCTTGAAAGCATCGAGGATGGCGTGAGCAAGCCCACACCGGC
GGTGATTAGCTCCTTGGGCGAGGAAGTACAACAACTTAATCATCTGATTGAAGATTTACGCACACTTTCCTTGGCCGATG
CAGGCCAGTTGACTCTCAATCCAATTGAGCTAGAACCCCAAGATGTGGTCAATCGTGCGGTCAATCGTATGCAGTTGGCG
GCACGCGAAAAACAATTGGAGCTAGCCAACGATAGCGCCGAACAGATCGATTTGGTCCATGCTGATCCATCACGCCTACA
ACAAGTGCTGGTTAATCTTTTGCAAAATGCCGTTCGCTACACCCCGCAAGGTGGTAAAATTCGCGTGACCGCCCGCCAAA
GTGCTGGTGAAGTTATTTTGGGTGTTCACGACACTGGTGCAGGCTTCGACCCAACCGAGGCTGCCACGATCTTCGAGCGC
TTTTATCGCACCGATAAAGCCCGCGCTCGTGATACGGGCGGCACAGGCTTGGGCTTGGCAATCGTCAAAGGTCTCGTGAC
CGCAATGGGTGGCCGGGTTTGGGCAACCAGTGTGCCGAACCAAGGTTCAAGTTTCTATGTTGCTTTACGAGCAATCAGCA
CCAAGGAGGGTGTATGA

Upstream 100 bases:

>100_bases
GCATATCAAAAATGTCCGCCGTAAGATCGAGCCAAATCCTAGCGTTCCGCGCTATATTTTGACGGTCTTTGGTGTGGGCT
ACAAATTTGCGGAATAAGCT

Downstream 100 bases:

>100_bases
CCGATTTGCCTGATGTAAGCGCAATGAACGAGTTTCAACGCGGCACACTTGCAGACACGCTTGGAATTAGCTTTACCGAA
GTCAGTTTGGATCGCGTAGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKLQRKLLLTHIAVALVAILLITAVANFTVNRYFSDLAAKQAKQAAQEFAPTLATCYQIIGSWDFNGQRCMQLGPRPFMP
PQFRHVVVVDTAGEIVFDSRGRGQINKPTNTITQRDIERGESINAEDGTVIGTVIVRPNQGQFGADEDYFLSMVRRNIWL
AGAITALLALAIGIGLARTLAAPLRSLTAAVHQLAQGERSVQVDDSGNDEIAELSQAFNTMSSELHRSEQVRRQMVADIA
HELRTPLSVLQIELESIEDGVSKPTPAVISSLGEEVQQLNHLIEDLRTLSLADAGQLTLNPIELEPQDVVNRAVNRMQLA
AREKQLELANDSAEQIDLVHADPSRLQQVLVNLLQNAVRYTPQGGKIRVTARQSAGEVILGVHDTGAGFDPTEAATIFER
FYRTDKARARDTGGTGLGLAIVKGLVTAMGGRVWATSVPNQGSSFYVALRAISTKEGV

Sequences:

>Translated_458_residues
MKLQRKLLLTHIAVALVAILLITAVANFTVNRYFSDLAAKQAKQAAQEFAPTLATCYQIIGSWDFNGQRCMQLGPRPFMP
PQFRHVVVVDTAGEIVFDSRGRGQINKPTNTITQRDIERGESINAEDGTVIGTVIVRPNQGQFGADEDYFLSMVRRNIWL
AGAITALLALAIGIGLARTLAAPLRSLTAAVHQLAQGERSVQVDDSGNDEIAELSQAFNTMSSELHRSEQVRRQMVADIA
HELRTPLSVLQIELESIEDGVSKPTPAVISSLGEEVQQLNHLIEDLRTLSLADAGQLTLNPIELEPQDVVNRAVNRMQLA
AREKQLELANDSAEQIDLVHADPSRLQQVLVNLLQNAVRYTPQGGKIRVTARQSAGEVILGVHDTGAGFDPTEAATIFER
FYRTDKARARDTGGTGLGLAIVKGLVTAMGGRVWATSVPNQGSSFYVALRAISTKEGV
>Mature_458_residues
MKLQRKLLLTHIAVALVAILLITAVANFTVNRYFSDLAAKQAKQAAQEFAPTLATCYQIIGSWDFNGQRCMQLGPRPFMP
PQFRHVVVVDTAGEIVFDSRGRGQINKPTNTITQRDIERGESINAEDGTVIGTVIVRPNQGQFGADEDYFLSMVRRNIWL
AGAITALLALAIGIGLARTLAAPLRSLTAAVHQLAQGERSVQVDDSGNDEIAELSQAFNTMSSELHRSEQVRRQMVADIA
HELRTPLSVLQIELESIEDGVSKPTPAVISSLGEEVQQLNHLIEDLRTLSLADAGQLTLNPIELEPQDVVNRAVNRMQLA
AREKQLELANDSAEQIDLVHADPSRLQQVLVNLLQNAVRYTPQGGKIRVTARQSAGEVILGVHDTGAGFDPTEAATIFER
FYRTDKARARDTGGTGLGLAIVKGLVTAMGGRVWATSVPNQGSSFYVALRAISTKEGV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=473, Percent_Identity=34.0380549682875, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=29.8701298701299, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=32.6271186440678, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1789149, Length=324, Percent_Identity=26.2345679012346, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=30.2521008403361, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1787894, Length=298, Percent_Identity=30.8724832214765, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=30.3703703703704, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=32.4786324786325, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790861, Length=380, Percent_Identity=28.6842105263158, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082128, Length=290, Percent_Identity=29.6551724137931, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=29.3172690763052, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=29.535864978903, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=25.8503401360544, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789808, Length=271, Percent_Identity=28.0442804428044, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=27.1493212669683, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790551, Length=279, Percent_Identity=27.5985663082437, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=28.2258064516129, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789403, Length=293, Percent_Identity=28.6689419795222, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=285, Percent_Identity=25.2631578947368, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49798; Mature: 49798

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQRKLLLTHIAVALVAILLITAVANFTVNRYFSDLAAKQAKQAAQEFAPTLATCYQII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSWDFNGQRCMQLGPRPFMPPQFRHVVVVDTAGEIVFDSRGRGQINKPTNTITQRDIERG
HCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHCC
ESINAEDGTVIGTVIVRPNQGQFGADEDYFLSMVRRNIWLAGAITALLALAIGIGLARTL
CCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPLRSLTAAVHQLAQGERSVQVDDSGNDEIAELSQAFNTMSSELHRSEQVRRQMVADIA
HHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLSVLQIELESIEDGVSKPTPAVISSLGEEVQQLNHLIEDLRTLSLADAGQLTLN
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
PIELEPQDVVNRAVNRMQLAAREKQLELANDSAEQIDLVHADPSRLQQVLVNLLQNAVRY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHHC
TPQGGKIRVTARQSAGEVILGVHDTGAGFDPTEAATIFERFYRTDKARARDTGGTGLGLA
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IVKGLVTAMGGRVWATSVPNQGSSFYVALRAISTKEGV
HHHHHHHHHCCEEEEECCCCCCCCEEEEEEEHHCCCCC
>Mature Secondary Structure
MKLQRKLLLTHIAVALVAILLITAVANFTVNRYFSDLAAKQAKQAAQEFAPTLATCYQII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSWDFNGQRCMQLGPRPFMPPQFRHVVVVDTAGEIVFDSRGRGQINKPTNTITQRDIERG
HCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHCC
ESINAEDGTVIGTVIVRPNQGQFGADEDYFLSMVRRNIWLAGAITALLALAIGIGLARTL
CCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAPLRSLTAAVHQLAQGERSVQVDDSGNDEIAELSQAFNTMSSELHRSEQVRRQMVADIA
HHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLSVLQIELESIEDGVSKPTPAVISSLGEEVQQLNHLIEDLRTLSLADAGQLTLN
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
PIELEPQDVVNRAVNRMQLAAREKQLELANDSAEQIDLVHADPSRLQQVLVNLLQNAVRY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHHC
TPQGGKIRVTARQSAGEVILGVHDTGAGFDPTEAATIFERFYRTDKARARDTGGTGLGLA
CCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IVKGLVTAMGGRVWATSVPNQGSSFYVALRAISTKEGV
HHHHHHHHHCCEEEEECCCCCCCCEEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]