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The map label for this gene is aroQ

Identifier: 159899492

GI number: 159899492

Start: 3752290

End: 3752724

Strand: Direct

Name: aroQ

Synonym: Haur_2973

Alternate gene names: 159899492

Gene position: 3752290-3752724 (Clockwise)

Preceding gene: 159899487

Following gene: 159899495

Centisome position: 59.12

GC content: 49.2

Gene sequence:

>435_bases
ATGCAGCTTTTAGTGCTACAAGGCCCAAATCTTAACATGCTTGGCCAACGTGAGCCAACAATTTATGGCTCAACCTCGCT
GGCCGATATTCATAACGCTATGCGCGAAAAAGCAACCAGCGCAGGCATCGAATTAAGCTTCATTCAATCGAACCATGAAG
GTGTATTAGTTGATACGCTCCACGCCCATTATGGCAAGATTCAGGGCATTATTATCAACCCAGGCGCGCTCACTCACTAT
GGTTTGAGCCTGCGCGATGGCTTAGCCTTGATGGATGTGCCGATCATCGAAGTGCATTTATCGAATGTCTATGCCCGTGA
AGCCTTTCGGCATCATTCAGTGGTGGCGGCAATTGCCCAAGGCCAAATTAGCGGGCTTGGTTGGCAAGGCTACCTGTATG
CGCTCGATTGGTTTATCCAGCGCAAATCGGCTTAA

Upstream 100 bases:

>100_bases
TAGTTCAAATTCCATCAATTAATTCTCGCTGGCTCCGATTGACATAGATTGAGCTTGGCCGCACAATGGCCTGCAATTTG
GCAATCAGGAGCAATTTCAA

Downstream 100 bases:

>100_bases
TCAGCCCATTGGTCAATAATCGCTGGATGCTGGCCCGCATGCAAAAGTTGTGATAATTGCTGATGCTCGGCGGCAATCAA
ACGCTTAACCAACTCGCCTA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MQLLVLQGPNLNMLGQREPTIYGSTSLADIHNAMREKATSAGIELSFIQSNHEGVLVDTLHAHYGKIQGIIINPGALTHY
GLSLRDGLALMDVPIIEVHLSNVYAREAFRHHSVVAAIAQGQISGLGWQGYLYALDWFIQRKSA

Sequences:

>Translated_144_residues
MQLLVLQGPNLNMLGQREPTIYGSTSLADIHNAMREKATSAGIELSFIQSNHEGVLVDTLHAHYGKIQGIIINPGALTHY
GLSLRDGLALMDVPIIEVHLSNVYAREAFRHHSVVAAIAQGQISGLGWQGYLYALDWFIQRKSA
>Mature_144_residues
MQLLVLQGPNLNMLGQREPTIYGSTSLADIHNAMREKATSAGIELSFIQSNHEGVLVDTLHAHYGKIQGIIINPGALTHY
GLSLRDGLALMDVPIIEVHLSNVYAREAFRHHSVVAAIAQGQISGLGWQGYLYALDWFIQRKSA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_HERA2 (A9B3N9)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545739.1
- ProteinModelPortal:   A9B3N9
- SMR:   A9B3N9
- GeneID:   5734845
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_2973
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   HAUR316274:HAUR_2973-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15802; Mature: 15802

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLVLQGPNLNMLGQREPTIYGSTSLADIHNAMREKATSAGIELSFIQSNHEGVLVDTL
CEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEC
HAHYGKIQGIIINPGALTHYGLSLRDGLALMDVPIIEVHLSNVYAREAFRHHSVVAAIAQ
CCCCCCEEEEEECCCCCEECCCCHHCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GQISGLGWQGYLYALDWFIQRKSA
CCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLLVLQGPNLNMLGQREPTIYGSTSLADIHNAMREKATSAGIELSFIQSNHEGVLVDTL
CEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEC
HAHYGKIQGIIINPGALTHYGLSLRDGLALMDVPIIEVHLSNVYAREAFRHHSVVAAIAQ
CCCCCCEEEEEECCCCCEECCCCHHCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GQISGLGWQGYLYALDWFIQRKSA
CCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA