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The map label for this gene is rsbU [H]

Identifier: 159899434

GI number: 159899434

Start: 3687861

End: 3689426

Strand: Direct

Name: rsbU [H]

Synonym: Haur_2915

Alternate gene names: 159899434

Gene position: 3687861-3689426 (Clockwise)

Preceding gene: 159899433

Following gene: 159899436

Centisome position: 58.11

GC content: 50.0

Gene sequence:

>1566_bases
ATGAAACTGCGTATTCCACTGATTATCAAGGTGTTGTTGCCGCTCCAAGTGATCATTATTGCGACGCTGATCTTTGCTGG
CCTGAGTTTTTATCGTGAAACCAACCAGCGTTGGCAACGCGAGATGGATACACGCTTGGCACGAGTCGTTGAATTGATTG
CCCGTGAGCTTGATCCAGCCTTGTTGAGTCAAATTGATGCGCCAGCTGATTTGTATACCGAGGCCTATACTACGCTGCAA
AAGCAATTGGCCCAAGCCCAAACTGCGGCCAACGTGGGCTTTATTGGCATTTTACGCCGCGATATCAAAACCCATCGTTT
GTATTATTGGGTCGATGTTGATAATACTGGCATCAACTATCCCTTCTTCTACGATACGCCTGAGCACTGGGCCGCCTTTG
AGGATGGCCAGCGCCATGCCGTGCGCTATGCCGATGAATTTGGCTCGTACTATGGCTTGGTTGCGCCAATTGTGGTTAAT
GATGCTCAAGGCCAGCCCTATGTGATTGCCATTGTCGAGGCTTCGCTGTCGGTTGAGGCGCGTGATCTGACCCAACAATC
GTTGATTAACCAACTGTTGCCATTGATTATTGGTGGCAGTCTGGTGGCGATTGCTTGTGCTTGGCTAGCGACGGTTTTTG
TGGTCAATCGGCCACTTCAGCGTTTGAAACATGGTGCGTTGCAACTTGCTGACGGCCATTTGGGTCATACCCTGCCTGAT
GATCAACGGGTTACCGATGAATTAACCGACCTGACGCGCACTTTTAATCTTATGTCGCAGCGGATTGCCAAGCTTTATAC
CGAGCAGAGCGAACGCGAACGAATGCTGAGCGAACTGCAAATTGCGCGAAATGTGCAACAAGCGCTGTTGCCGAAACGCC
TTCCAAGCGTGGCTGGGCTTGAAGTTGCCGCAATTTGTTTGCCCCAACGCGAGACCTCAGGCGATTTCTATGGCGTAATC
GCTCAAGGCAGCAGTACCGTTGATCTGATGATTGGCGATGTTTCGGGCAAGAGCGTGCCTGCCGCCTTAGTAATGGTCGC
AACTTACAGCACCCTCCGCGCCTTGGCTGGCACTCAAGCGACTCCAGCGATGATTCTTGATCAAACTAATACTAGTTTAG
TGCAAAATATTCCCCGTAGTATGTTTGCGGCGGTGAGCTATGCTCGGATCGATGCCTTGGCTCGCACCTTGGTTTGGGCC
AATGCTGGCCAAGTATACCCATTTTTAATTCATAGCAGTCGCAACCAGCCAGAGTTTCCTGAATATTTGACTGGGCGCGG
CCAATCATTGCCGCTTGGCATCACACCATTAATTCAATATGAAGATAGCCCAATTCAATGTAATCATGGCGATATGCTGT
TGTTTTTCACCGATGGAATTGTCGAAGCCATGAATAGCAGCGACGAAATGTATGGCTTCGAGCGTTTAGAAGATTTGGTG
CGCTCATTGCCAGCCGATATTCATGCTCAAGCCTTGCTCGATGCTGTGCTCAACGACGTGCAAGACTTTGCCAACCATAC
CGAGCAACACGACGATATTACGATGCTGGCCGTGAAGTTTGTGTAG

Upstream 100 bases:

>100_bases
CGTTTCACAACAATCATGTTTATGCTGCCGACGCTTATAACAACACGATTTGGCGCTTTAATGCCGATGGTAGCAATCCA
CAACGCTTGGGGAGCGAGCA

Downstream 100 bases:

>100_bases
CGTGGGGATTAGTTGGCAGGGATTAGAACTCGAGTTATTGGTCCTCAAAACACTTGAGTTAATGGTGTAGCTACAATTTA
ACCCAGAGACGCAGAGTTCT

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MKLRIPLIIKVLLPLQVIIIATLIFAGLSFYRETNQRWQREMDTRLARVVELIARELDPALLSQIDAPADLYTEAYTTLQ
KQLAQAQTAANVGFIGILRRDIKTHRLYYWVDVDNTGINYPFFYDTPEHWAAFEDGQRHAVRYADEFGSYYGLVAPIVVN
DAQGQPYVIAIVEASLSVEARDLTQQSLINQLLPLIIGGSLVAIACAWLATVFVVNRPLQRLKHGALQLADGHLGHTLPD
DQRVTDELTDLTRTFNLMSQRIAKLYTEQSERERMLSELQIARNVQQALLPKRLPSVAGLEVAAICLPQRETSGDFYGVI
AQGSSTVDLMIGDVSGKSVPAALVMVATYSTLRALAGTQATPAMILDQTNTSLVQNIPRSMFAAVSYARIDALARTLVWA
NAGQVYPFLIHSSRNQPEFPEYLTGRGQSLPLGITPLIQYEDSPIQCNHGDMLLFFTDGIVEAMNSSDEMYGFERLEDLV
RSLPADIHAQALLDAVLNDVQDFANHTEQHDDITMLAVKFV

Sequences:

>Translated_521_residues
MKLRIPLIIKVLLPLQVIIIATLIFAGLSFYRETNQRWQREMDTRLARVVELIARELDPALLSQIDAPADLYTEAYTTLQ
KQLAQAQTAANVGFIGILRRDIKTHRLYYWVDVDNTGINYPFFYDTPEHWAAFEDGQRHAVRYADEFGSYYGLVAPIVVN
DAQGQPYVIAIVEASLSVEARDLTQQSLINQLLPLIIGGSLVAIACAWLATVFVVNRPLQRLKHGALQLADGHLGHTLPD
DQRVTDELTDLTRTFNLMSQRIAKLYTEQSERERMLSELQIARNVQQALLPKRLPSVAGLEVAAICLPQRETSGDFYGVI
AQGSSTVDLMIGDVSGKSVPAALVMVATYSTLRALAGTQATPAMILDQTNTSLVQNIPRSMFAAVSYARIDALARTLVWA
NAGQVYPFLIHSSRNQPEFPEYLTGRGQSLPLGITPLIQYEDSPIQCNHGDMLLFFTDGIVEAMNSSDEMYGFERLEDLV
RSLPADIHAQALLDAVLNDVQDFANHTEQHDDITMLAVKFV
>Mature_521_residues
MKLRIPLIIKVLLPLQVIIIATLIFAGLSFYRETNQRWQREMDTRLARVVELIARELDPALLSQIDAPADLYTEAYTTLQ
KQLAQAQTAANVGFIGILRRDIKTHRLYYWVDVDNTGINYPFFYDTPEHWAAFEDGQRHAVRYADEFGSYYGLVAPIVVN
DAQGQPYVIAIVEASLSVEARDLTQQSLINQLLPLIIGGSLVAIACAWLATVFVVNRPLQRLKHGALQLADGHLGHTLPD
DQRVTDELTDLTRTFNLMSQRIAKLYTEQSERERMLSELQIARNVQQALLPKRLPSVAGLEVAAICLPQRETSGDFYGVI
AQGSSTVDLMIGDVSGKSVPAALVMVATYSTLRALAGTQATPAMILDQTNTSLVQNIPRSMFAAVSYARIDALARTLVWA
NAGQVYPFLIHSSRNQPEFPEYLTGRGQSLPLGITPLIQYEDSPIQCNHGDMLLFFTDGIVEAMNSSDEMYGFERLEDLV
RSLPADIHAQALLDAVLNDVQDFANHTEQHDDITMLAVKFV

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 57987; Mature: 57987

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRIPLIIKVLLPLQVIIIATLIFAGLSFYRETNQRWQREMDTRLARVVELIARELDPA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LLSQIDAPADLYTEAYTTLQKQLAQAQTAANVGFIGILRRDIKTHRLYYWVDVDNTGINY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEEEEEEECCCCCCC
PFFYDTPEHWAAFEDGQRHAVRYADEFGSYYGLVAPIVVNDAQGQPYVIAIVEASLSVEA
CEECCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEEEEEECCCCCCEEEEEEECCCCCHH
RDLTQQSLINQLLPLIIGGSLVAIACAWLATVFVVNRPLQRLKHGALQLADGHLGHTLPD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
DQRVTDELTDLTRTFNLMSQRIAKLYTEQSERERMLSELQIARNVQQALLPKRLPSVAGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EVAAICLPQRETSGDFYGVIAQGSSTVDLMIGDVSGKSVPAALVMVATYSTLRALAGTQA
EEEEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
TPAMILDQTNTSLVQNIPRSMFAAVSYARIDALARTLVWANAGQVYPFLIHSSRNQPEFP
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCC
EYLTGRGQSLPLGITPLIQYEDSPIQCNHGDMLLFFTDGIVEAMNSSDEMYGFERLEDLV
HHHCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEECHHHHHHCCCCHHHHHHHHHHHH
RSLPADIHAQALLDAVLNDVQDFANHTEQHDDITMLAVKFV
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure
MKLRIPLIIKVLLPLQVIIIATLIFAGLSFYRETNQRWQREMDTRLARVVELIARELDPA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LLSQIDAPADLYTEAYTTLQKQLAQAQTAANVGFIGILRRDIKTHRLYYWVDVDNTGINY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEEEEEEECCCCCCC
PFFYDTPEHWAAFEDGQRHAVRYADEFGSYYGLVAPIVVNDAQGQPYVIAIVEASLSVEA
CEECCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEEEEEECCCCCCEEEEEEECCCCCHH
RDLTQQSLINQLLPLIIGGSLVAIACAWLATVFVVNRPLQRLKHGALQLADGHLGHTLPD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCC
DQRVTDELTDLTRTFNLMSQRIAKLYTEQSERERMLSELQIARNVQQALLPKRLPSVAGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EVAAICLPQRETSGDFYGVIAQGSSTVDLMIGDVSGKSVPAALVMVATYSTLRALAGTQA
EEEEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
TPAMILDQTNTSLVQNIPRSMFAAVSYARIDALARTLVWANAGQVYPFLIHSSRNQPEFP
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCC
EYLTGRGQSLPLGITPLIQYEDSPIQCNHGDMLLFFTDGIVEAMNSSDEMYGFERLEDLV
HHHCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEECHHHHHHCCCCHHHHHHHHHHHH
RSLPADIHAQALLDAVLNDVQDFANHTEQHDDITMLAVKFV
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]