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The map label for this gene is yycF [H]

Identifier: 159899244

GI number: 159899244

Start: 3480060

End: 3480740

Strand: Direct

Name: yycF [H]

Synonym: Haur_2725

Alternate gene names: 159899244

Gene position: 3480060-3480740 (Clockwise)

Preceding gene: 159899243

Following gene: 159899246

Centisome position: 54.83

GC content: 48.46

Gene sequence:

>681_bases
ATGGAACAACCGTTAATTTTAGTTGTAGACGATGAACCCGATGTTGCCCAGTTGTTGTCGTTGCAATTGACCATGGAAAA
ATATCGGGTTCAAATTGCCTACGACGGTCCAACCGCCATCGAGTATGTCCGCTCACTCACACCCGATTTAATTATCTTGG
ATGTGATGTTGCCTGCCATGGACGGCTACGAAACTTGCCGTCGAATTCGCGAGTTCAGCAATGTGCCCATTTTGATGCTG
ACCGCCAATATTCAAGACCAGCAAATTGTCTCAGGTTTGGATAGTGGGGCCGATGATTATGTCACCAAGCCCTATAGCCC
AAGCCAATTGTTAGCACGGGTTCGGGCTTTGTTGCGCCGGATTCCACCGCAACGGCCAATTATCACCGCTGGCGAAGGCT
TGATGGTGCTGGATCGACAACGCCGCGAATTGAAAGTCAAAGATAAAGTGATCGATCTCACGCCAACCGAATATCAATTG
TTGATTTTGCTGGCTGATAGTGTTGGGCAAGTTGTGCCGCACGAAAAATTGCTTGGCTCGATTTGGGGCAGTGGCAAAGA
ATCAGATCACGATTCGCTGAAAGTCTATATCTGGCATTTACGGCGTAAATTAGAGGACAATCCCCGTCAGCCGAAAATTC
TGCTGACCGAATGGGGTGTTGGCTATCGCCTAGCTGAGTAA

Upstream 100 bases:

>100_bases
CTCGGATTAATGCGATTACAGAGTCTGAGATGGATCATGTATTATCGGAATTATTGCCCTAAAAAATCGGGTTAGTGTTT
TTGGAGAGGATCTCTCACTT

Downstream 100 bases:

>100_bases
CCTAGTTTGCTTGTGGATTGAGGAATAAGCGGCACGATCAACGAGGATCGCGCCGCTTTGGCATTTTAGCGGGTGGCCCA
AGGGGCAAATTGATGGTAGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAMDGYETCRRIREFSNVPILML
TANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRRIPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQL
LILLADSVGQVVPHEKLLGSIWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE

Sequences:

>Translated_226_residues
MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAMDGYETCRRIREFSNVPILML
TANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRRIPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQL
LILLADSVGQVVPHEKLLGSIWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE
>Mature_226_residues
MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAMDGYETCRRIREFSNVPILML
TANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRRIPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQL
LILLADSVGQVVPHEKLLGSIWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=40.2714932126697, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.2342342342342, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=34.8214285714286, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=32.5892857142857, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=34.6666666666667, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=34.061135371179, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=34.375, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=33.4862385321101, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=29.1845493562232, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.8947368421053, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=31.0810810810811, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1790552, Length=205, Percent_Identity=34.6341463414634, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=34.0740740740741, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=35.9223300970874, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=133, Percent_Identity=37.593984962406, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=119, Percent_Identity=32.7731092436975, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25740; Mature: 25740

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAM
CCCCEEEEECCCCCHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEHHHCCC
DGYETCRRIREFSNVPILMLTANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRR
CCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
IPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQLLILLADSVGQVVPHEKLLGS
CCCCCCEEECCCCEEEEECCHHHEEHHHEEEECCCCCEEEEEEEECHHCCCCCHHHHHHH
IWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECC
>Mature Secondary Structure
MEQPLILVVDDEPDVAQLLSLQLTMEKYRVQIAYDGPTAIEYVRSLTPDLIILDVMLPAM
CCCCEEEEECCCCCHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEHHHCCC
DGYETCRRIREFSNVPILMLTANIQDQQIVSGLDSGADDYVTKPYSPSQLLARVRALLRR
CCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
IPPQRPIITAGEGLMVLDRQRRELKVKDKVIDLTPTEYQLLILLADSVGQVVPHEKLLGS
CCCCCCEEECCCCEEEEECCHHHEEHHHEEEECCCCCEEEEEEEECHHCCCCCHHHHHHH
IWGSGKESDHDSLKVYIWHLRRKLEDNPRQPKILLTEWGVGYRLAE
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]