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The map label for this gene is pleC [H]

Identifier: 159898358

GI number: 159898358

Start: 2131839

End: 2133548

Strand: Reverse

Name: pleC [H]

Synonym: Haur_1834

Alternate gene names: 159898358

Gene position: 2133548-2131839 (Counterclockwise)

Preceding gene: 159898362

Following gene: 159898357

Centisome position: 33.62

GC content: 44.15

Gene sequence:

>1710_bases
ATGGATTTAAATGAATTTGAATCGGTGCGTAAGCTGCGCAAAACTGCGTTTAAATATTGCTGTGGAATTGCGTTGGGATT
AACTATATATTCCATATTATTTGTCATCTTTGCCTATGATGAAATCAATTATGAAGTTATTGCTATGGCCATATTATATA
TAATTATGTTATTCTTTTTCTCTGAAAGATATTCATTTAAAGGAATTGTTTTAAGTATTACTGGATTCTTGTATGTTATC
TATGTAGCAGGTGATGGAGATCGCTTAAATGGATTAATATCCGATCATACTATATTATTTTTATTACCAATTATTATGGT
TGGATTAATTAGTGGCTCATTTAGAATGATTTTAAGTGGTTTTTTTAATATAGGATTAGTATTTATCTTTTTTTATATTT
ATCAAGCTGAAATTAGATCGATAACGTATTATAATTTACTTTTTTTAAGCATCGTAATTTTCCTACTCTGGTTGCTCGTG
CGGGCACTCGAAAACGCTCTGCGCCAATCGCTTCATCTCCAAGCCAATTTGCAACATTTGGTCGATGAGCGCACGGCTCA
ATTAGCCACCAGCGTGCAAGAAGCCAAATCGGCTCAGCGCCTTGCCGAGCAAGCCAACCTGCGCAAATCACAATTTTTGG
CCACCATGAGCCACGAATTGCGCACGCCACTCAATGCGATCATCAATATGACCGAGTTTATCGATTGGTTCGGCCCTCTC
AACAGCCAACAAAAAAGCTACCAAGATCAAGTTCGCGGCGCTGGCGAACATCTCCTCCACCTCATCAACGACATTTTAGA
TTTATCGAAGATCGAAGCTGGCCGCATCGAATTACAATTCGGCCAAGTCGATTGTGGTGATATCGCCCAAGAAGTCTTGG
AAACCGTGCGGCCTTTAGCCGAATCAAAAGGTTTACAAATTGCCTACCATCATGCCGATGGCACTGGCTTGGCCTGGGCT
GATAGTAAAGCGATTAAACAAATCGTCTTGAATTTGCTCTCGAATGCGATCAAATTTACTGAAACTGGCCAGATTCGGGT
GGCTCTGGAGTTTTCCGCGACAACCGTCAATATCAGCGTGCACGATACCGGGATTGGCATCGCCCGCGAACAACAGCAGT
TTATCTGGGAATCGTTTCGCCAAATTCAAAGTGCCGATGACCGTGAATATGAGGGCACTGGCTTAGGCATGAGTATCACC
AAACAACTTGTCGATTTGCATGGCGGCAACATTACCGTCGAAAGCGAGCTTGGCCAAGGAACCCAATTTCAAGTGTGTCT
GCCCACCAAAGCTGCGTGGGAGCAGCGTCACAAAAGTTATGTCAAATCAACAAGCAATCAAACGATCTTAGTCGTTGATG
ATAATCCCAACACGGTTGCCGAATTTGGCCAGCAGCTCCAAGCTACCAATTGGAGCATCGTAAGTTGTTTGGATAGTCGC
GAGGCGCTGGCGATCTATCAACAGGAAGAGCCAGCGATCGTTGTCTTGGATGCGACGTTAGCCTTTGTCAGTGCGCATAG
CTTGATCGATGCAATCGTAGCCAGTAACCCCGATCAGGCGCTAGTAATCATCACGCCAACCAATGATTATAGTGTGGGTT
TGGATGCGTGGCCAAGCATTACCCGCCCATGGCCTCACGCCTTGGATGATTTCCTGCACCAAACCCTTACGCAAGCCCAA
CAGCAGCAACAGCTCGCATCACAGCCCTAG

Upstream 100 bases:

>100_bases
TGGCTGGCGTATACTCATACTAAGCCATGATCTGCCTGCCACCGCCAGTGCTCTATGCCAGCACTTGGTTGATCGTGGCT
GCCGAACAAGGAGTTTTTTG

Downstream 100 bases:

>100_bases
CCGATAAGAGAACTCACGTTTTAGGAGGAAGAATAGAATGCTCACAGCAACAACCCAAATCTCAGCAGGGGTGATTGAAG
ATAACCCACAAAATTTAGAA

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFFSERYSFKGIVLSITGFLYVI
YVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSGFFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLV
RALENALRQSLHLQANLQHLVDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPL
NSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLAESKGLQIAYHHADGTGLAWA
DSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISVHDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSIT
KQLVDLHGGNITVESELGQGTQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSR
EALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSITRPWPHALDDFLHQTLTQAQ
QQQQLASQP

Sequences:

>Translated_569_residues
MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFFSERYSFKGIVLSITGFLYVI
YVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSGFFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLV
RALENALRQSLHLQANLQHLVDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPL
NSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLAESKGLQIAYHHADGTGLAWA
DSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISVHDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSIT
KQLVDLHGGNITVESELGQGTQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSR
EALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSITRPWPHALDDFLHQTLTQAQ
QQQQLASQP
>Mature_569_residues
MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFFSERYSFKGIVLSITGFLYVI
YVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSGFFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLV
RALENALRQSLHLQANLQHLVDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPL
NSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLAESKGLQIAYHHADGTGLAWA
DSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISVHDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSIT
KQLVDLHGGNITVESELGQGTQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSR
EALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSITRPWPHALDDFLHQTLTQAQ
QQQQLASQP

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=35.7692307692308, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=28.0839895013123, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=33.9920948616601, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=30.8290155440415, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI48994928, Length=346, Percent_Identity=27.7456647398844, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=26.7782426778243, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28.4444444444444, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=29.3333333333333, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=320, Percent_Identity=24.0625, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=285, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788279, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=320, Percent_Identity=25.9375, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63785; Mature: 63785

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SERYSFKGIVLSITGFLYVIYVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSG
HCCCCCCHHHHHEECEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLVRALENALRQSLHLQANLQHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
NSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ESKGLQIAYHHADGTGLAWADSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISV
HCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEE
HDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSITKQLVDLHGGNITVESELGQG
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
TQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSR
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCC
EALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSI
CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCC
TRPWPHALDDFLHQTLTQAQQQQQLASQP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLNEFESVRKLRKTAFKYCCGIALGLTIYSILFVIFAYDEINYEVIAMAILYIIMLFFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SERYSFKGIVLSITGFLYVIYVAGDGDRLNGLISDHTILFLLPIIMVGLISGSFRMILSG
HCCCCCCHHHHHEECEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FFNIGLVFIFFYIYQAEIRSITYYNLLFLSIVIFLLWLLVRALENALRQSLHLQANLQHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDERTAQLATSVQEAKSAQRLAEQANLRKSQFLATMSHELRTPLNAIINMTEFIDWFGPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
NSQQKSYQDQVRGAGEHLLHLINDILDLSKIEAGRIELQFGQVDCGDIAQEVLETVRPLA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ESKGLQIAYHHADGTGLAWADSKAIKQIVLNLLSNAIKFTETGQIRVALEFSATTVNISV
HCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEE
HDTGIGIAREQQQFIWESFRQIQSADDREYEGTGLGMSITKQLVDLHGGNITVESELGQG
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
TQFQVCLPTKAAWEQRHKSYVKSTSNQTILVVDDNPNTVAEFGQQLQATNWSIVSCLDSR
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHCCC
EALAIYQQEEPAIVVLDATLAFVSAHSLIDAIVASNPDQALVIITPTNDYSVGLDAWPSI
CCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCC
TRPWPHALDDFLHQTLTQAQQQQQLASQP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]