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The map label for this gene is yogA [H]

Identifier: 159898029

GI number: 159898029

Start: 1753209

End: 1754210

Strand: Reverse

Name: yogA [H]

Synonym: Haur_1504

Alternate gene names: 159898029

Gene position: 1754210-1753209 (Counterclockwise)

Preceding gene: 159898030

Following gene: 159898028

Centisome position: 27.64

GC content: 51.6

Gene sequence:

>1002_bases
ATGCAAGCAATTATCTATCGTGAATATGGCTCAGCCGATGTGTTGCGGCTCAGCGAAGTAGCTCGCCCAACCCCTGCTGA
AAATCAAGTTTTAATTAAAGTACATATGACAGCCCTTAACGCCGCCGATTGGCGCTTGATGTCTGGTAAACCCTTTCCTG
TACGCTTTATGACGGGCTTATTCAAACCCAAAAAAGGTATTCCTGGCACCGATGTGGCTGGAGTTATCGAAGCCGTCGGG
CGTAACGTCACTCAATTTAAAGTCGGCGATGCGGTGTTTGGCGATCTTTCGGGCTGCGGAGCTGGTGGCTTAGGCCAATA
TGTTTGTGCCCCCGAACATGTGCTGGTGCTCAAGCCCGAGCAGCTAAGTTTTGAACAAGCTGCTGCCGCGCCCATGGCCG
CGGTCACAGCCTTGCAAGGCCTGCGCCAAGGCGGCATCGCCGCAGGCCAAAAGGTCTTGATTTATGGAGCTTCAGGTGGA
ATTGGCACATTTGCGGTGCAGCTTGCTAAACATTTTGGCGCAATCGTTACCGCTGTTTCCAGTGCCGCCAAGCACGATTT
GCTACGTTCGCTCGGCGCTGATCAGGTGCTGGATTATGCTAAGGATGATTTTGCTCGCAATGGTCAGCTGTATGATCTGA
TTTTGGGGGTCAATGGTCATCGCTCAATTTTCGACTATAAACGCAGTTTAGCGCCTCAAGGTCGCTATGTGATGGTTGGC
GGCGAAATGAGCCAGATTTTTCAGGCGATCGCCTTGGGCAAATTGCTCTCAATTGGCAGCCAAAAACAGCTGAGTAACCT
GTTCGCCAAGCCCAACCAAACCGATCTCGCCAAAATTGGCTTTTTGCTGGCCAACGGCGATATCAAAGCGGTGATCGATC
AGCGCTACCCGCTGGAAGAAGCTCCTGCCGCAATGCGTTATCTCCAAGCTGGCCATGCCAAAGGCAAAATTATGATCGAA
TTGCAACCCACCACAGCTCAAAGCTTGGAGCAAACCGTATGA

Upstream 100 bases:

>100_bases
TCGCGATTTGGGCATGCAATTAATTTCAATTATGCCCGTGCCGCCAACCACGCTCGAATCCGATTCAACTGAGCAATAAC
AAACAACCTGGAGTTTTACC

Downstream 100 bases:

>100_bases
AAGCAATGCTCTGCACAGGTTATGGCTCGCCCGATGTCTTACAATTTGGCGAAGCTAGCAAACCAGCCCCCAAAGCCAAT
GAATTATTAATTCGAGTGCA

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGLFKPKKGIPGTDVAGVIEAVG
RNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPEQLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGG
IGTFAVQLAKHFGAIVTAVSSAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVG
GEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEEAPAAMRYLQAGHAKGKIMIE
LQPTTAQSLEQTV

Sequences:

>Translated_333_residues
MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGLFKPKKGIPGTDVAGVIEAVG
RNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPEQLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGG
IGTFAVQLAKHFGAIVTAVSSAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVG
GEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEEAPAAMRYLQAGHAKGKIMIE
LQPTTAQSLEQTV
>Mature_333_residues
MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGLFKPKKGIPGTDVAGVIEAVG
RNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPEQLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGG
IGTFAVQLAKHFGAIVTAVSSAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVG
GEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEEAPAAMRYLQAGHAKGKIMIE
LQPTTAQSLEQTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=364, Percent_Identity=30.2197802197802, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI194239674, Length=339, Percent_Identity=32.1533923303835, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI13236495, Length=339, Percent_Identity=32.1533923303835, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI22538446, Length=347, Percent_Identity=31.9884726224784, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI22538444, Length=347, Percent_Identity=31.9884726224784, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=31.9018404907975, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI24308257, Length=354, Percent_Identity=25.4237288135593, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI18379349, Length=325, Percent_Identity=26.4615384615385, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI90669511, Length=347, Percent_Identity=27.0893371757925, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI28557745, Length=330, Percent_Identity=26.0606060606061, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=334, Percent_Identity=28.7425149700599, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082125, Length=194, Percent_Identity=30.4123711340206, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789651, Length=217, Percent_Identity=29.0322580645161, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=339, Percent_Identity=26.2536873156342, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71987554, Length=365, Percent_Identity=24.6575342465753, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=226, Percent_Identity=28.3185840707965, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=273, Percent_Identity=27.1062271062271, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=25, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=225, Percent_Identity=28.4444444444444, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581339, Length=375, Percent_Identity=24.2666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24581341, Length=374, Percent_Identity=24.5989304812834, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550423, Length=268, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35454; Mature: 35454

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGL
CCEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCEEEECCCCCCHHHHHHC
FKPKKGIPGTDVAGVIEAVGRNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPE
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCCCCEEECCCEEEEECCC
QLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGGIGTFAVQLAKHFGAIVTAVS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVG
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEC
GEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHEEEEECCCEEEEECCCCCCHH
APAAMRYLQAGHAKGKIMIELQPTTAQSLEQTV
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MQAIIYREYGSADVLRLSEVARPTPAENQVLIKVHMTALNAADWRLMSGKPFPVRFMTGL
CCEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCEEEECCCCCCHHHHHHC
FKPKKGIPGTDVAGVIEAVGRNVTQFKVGDAVFGDLSGCGAGGLGQYVCAPEHVLVLKPE
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCCCCEEECCCEEEEECCC
QLSFEQAAAAPMAAVTALQGLRQGGIAAGQKVLIYGASGGIGTFAVQLAKHFGAIVTAVS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SAAKHDLLRSLGADQVLDYAKDDFARNGQLYDLILGVNGHRSIFDYKRSLAPQGRYVMVG
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEC
GEMSQIFQAIALGKLLSIGSQKQLSNLFAKPNQTDLAKIGFLLANGDIKAVIDQRYPLEE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHEEEEECCCEEEEECCCCCCHH
APAAMRYLQAGHAKGKIMIELQPTTAQSLEQTV
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]