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The map label for this gene is rocF [H]

Identifier: 159897759

GI number: 159897759

Start: 1424292

End: 1425218

Strand: Reverse

Name: rocF [H]

Synonym: Haur_1230

Alternate gene names: 159897759

Gene position: 1425218-1424292 (Counterclockwise)

Preceding gene: 159897762

Following gene: 159897757

Centisome position: 22.46

GC content: 54.48

Gene sequence:

>927_bases
GTGCTAATCGATCTTATCGGTGTCCCGCTCGATTTGGGTGCAGGGCGGCGTGGCGTGGACATGGGGCCAAGTGCAATTCG
TTATGCAGGCTTACGTTCACAATTAGAAGAGCTTGGTCATACCGTGATTGATCGCGGCAATCTCACGGCGAGCATCGCTG
AAACTCTGCCCGTCGGCGACTTAACGTTGCGCTATTTCGAGCCAATTCGCGATACCTTGATTCAATTAGCTAGCGAGGTT
GATCAGTCGTGTAGCCAAGGCCATGTGCCAGTGGTGCTCGGTGGCGATCATAGCCTTGGTTTGGGTTCGGTTAGCGGAGC
CGCCCACAATCGCGATATTGGGGTGCTCTGGATCGATGCCCATGGCGATTTTAATATTCCCAGCACCTCGCCTTCGGGCA
ATATTCATGGCATGCCCTTGGCAGCACTGTGTGGCTACGGCGACGAACGCTTGATCCATTTGAGTGGTCAGCGCTTAGCA
AACTCTATGATTAACCCGCATCGCGTGGCATTGGTTGCGGTGCGCGACCTTGACCCCGAGGAGCGTCAACTGCTCACCGA
AGCTGGCGTGCAAGTCTTTGCCACTGAATATATCGATCGTTATGGCATGTATGAAACCATGGTACGGGCGATCAGCGTTG
CCAACCAAGCTCGCGATGGTTTTTATGTTAGCTTCGATCTGGATGTGCTTGATCCTGCGGTTGCGCCTGGGGTTGGCACA
CCCGTGCCTGGCGGCTTAACCTATCGCGAAGCCCACTTGGCCGCCGAATTGATCGCCGAATCAGGGCGCATGATTGGCTT
AGATATTGTCGAAGTCAACCCAATTCTTGATGATCGCAATTGCACAGCGACGGTTGCGGTGGAAATAGCGCTCTCCGCGC
TTGGTAAACGGGTTTGGCACAAACAGCATCCACGCACTGCCCTCTAA

Upstream 100 bases:

>100_bases
ACATGCTCAGCAATTGCCCTCAAGCTGCCAGCTATCGGTTAAAATACGCCTAGGCTTTCATTCAATGGTGCATGAAAGCG
ACATTCACTAGGAGGTTCTT

Downstream 100 bases:

>100_bases
AATTAACGCAACAGGCGGGGCAAATGCCCCGCCTGCTGATCTCCAAAGGATTTAAGCGTTATTCCGCCCGAATCGCAAAG
GGCAGCCAAATTTTCCATTC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGDLTLRYFEPIRDTLIQLASEV
DQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDAHGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLA
NSMINPHRVALVAVRDLDPEERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGT
PVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWHKQHPRTAL

Sequences:

>Translated_308_residues
MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGDLTLRYFEPIRDTLIQLASEV
DQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDAHGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLA
NSMINPHRVALVAVRDLDPEERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGT
PVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWHKQHPRTAL
>Mature_308_residues
MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGDLTLRYFEPIRDTLIQLASEV
DQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDAHGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLA
NSMINPHRVALVAVRDLDPEERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGT
PVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWHKQHPRTAL

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=303, Percent_Identity=37.953795379538, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI10947139, Length=308, Percent_Identity=36.3636363636364, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI37537722, Length=298, Percent_Identity=27.1812080536913, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789306, Length=280, Percent_Identity=26.4285714285714, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996843, Length=219, Percent_Identity=36.986301369863, Blast_Score=140, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6325146, Length=322, Percent_Identity=31.3664596273292, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24638886, Length=305, Percent_Identity=34.0983606557377, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32991; Mature: 32991

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGD
CEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCH
LTLRYFEPIRDTLIQLASEVDQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
HGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLANSMINPHRVALVAVRDLDPE
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEECHHHHHHHCCCCCEEEEEEEECCCHH
ERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGT
HHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCCC
PVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWH
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH
KQHPRTAL
HCCCCCCC
>Mature Secondary Structure
MLIDLIGVPLDLGAGRRGVDMGPSAIRYAGLRSQLEELGHTVIDRGNLTASIAETLPVGD
CEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCH
LTLRYFEPIRDTLIQLASEVDQSCSQGHVPVVLGGDHSLGLGSVSGAAHNRDIGVLWIDA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
HGDFNIPSTSPSGNIHGMPLAALCGYGDERLIHLSGQRLANSMINPHRVALVAVRDLDPE
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEECHHHHHHHCCCCCEEEEEEEECCCHH
ERQLLTEAGVQVFATEYIDRYGMYETMVRAISVANQARDGFYVSFDLDVLDPAVAPGVGT
HHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCCCC
PVPGGLTYREAHLAAELIAESGRMIGLDIVEVNPILDDRNCTATVAVEIALSALGKRVWH
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH
KQHPRTAL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]