Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 159897724

GI number: 159897724

Start: 1377217

End: 1378281

Strand: Reverse

Name: gcp [H]

Synonym: Haur_1195

Alternate gene names: 159897724

Gene position: 1378281-1377217 (Counterclockwise)

Preceding gene: 159897728

Following gene: 159897716

Centisome position: 21.72

GC content: 53.43

Gene sequence:

>1065_bases
ATGTCACAGCAAATGCCCGCAGGTTTTACGATTTTAGCAATTGAAACATCGTGCGATGAAACCGCCGCCGCCGTTATTCG
CGATGGCCGCGAGATTGTGGCCAATAGCGTCGCTTCACAAATCGATATTCATCAACGCTATGGTGGCGTTGTGCCCGAAG
TGGCTTCGCGCCAACATATTCTGACGATTACACCCGTGATTAATACGGTGCTGGCCCAAGTGCCCGGCGGTTGGAGCGCG
ATTAATGCGGTTGCCACAACTTATGGACCAGGCTTAGCTGGCGCTTTATTAACTGGAATTAACACCGCCAAGGCGATTGC
GTGGTCGCGCAATTTGCCGTTTATCGGGGTTAATCACCTCGAAGGCCATATTTATGCTTCGTGGCTGCATACTGCCAAAG
ATCTAGCCTACCAAGCCCCCGAATTTCCGTGTGTCGCCTTGATTGTTTCTGGTGGCCACACGGCCTTGGTGTTGCTCAAC
GATCATGGTGATTATCGTTTGCTTGGGCAAACCCGCGATGATGCAGTGGGCGAGGCTTTCGATAAGGTAGCGCGAATTAT
GGGCTTGGGCTATCCAGGCGGCCCGCAAATGGAAAAAGTCGCGCGTGGGGTTAATCCAGGTGCACTCAAATTGCCCCGAG
CATGGTTGCGCGGAACCTACGATTGGAGCTTTAGCGGCCTCAAAACCGCTGTGCTGAACGTGGTCAATGATCGTTTGGGT
GAGCGCATGGAGAAAGTTAAACTTGCTGAAGTTGACCCAGCCTTCACCGCCCAGCTTGCCGCTGCCTTCCAAGATTCGGC
AGTCGATGTGTTGGTGCAAAAAACCGTGGCTGCTGCTCGCGAATACAAAGCCAAAACGATTATTTTAGCTGGTGGCGTAG
CCGCAAATACTGCCTTACGCGAGCGCTTGAGCGCAACCGCCAAGCCTATTCCGGTAGCCTACCCGCCAATTTGGCTGTGT
ACCGATAATGCCGCCATGATCGGCGCTGCCGCCTATTATCGTTATCAAGCAGGCGTGCAGCAGGATTGGTCGCTCGATGC
CACTCCCAGTCTCAAGCTGATTTAA

Upstream 100 bases:

>100_bases
ACGGGGTGTTGTCGTTTTTACCACTCATATCATGCCATAGCCACGGCACAGCGTCAATGTAGCGCAACTGACAGCTAGGT
GAAATAGAACGTAGGAATTC

Downstream 100 bases:

>100_bases
GGGGTAATTTTAACCACGAAGAGCACGAAGGGAGTATGGCTGTAGGCTATGAGGCTATTGGCTATCGGAATATTTTCTAG
CATTTCAAATGATCCAAAAG

Product: metalloendopeptidase glycoprotease family

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHILTITPVINTVLAQVPGGWSA
INAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHLEGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLN
DHGDYRLLGQTRDDAVGEAFDKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLG
ERMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALRERLSATAKPIPVAYPPIWLC
TDNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI

Sequences:

>Translated_354_residues
MSQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHILTITPVINTVLAQVPGGWSA
INAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHLEGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLN
DHGDYRLLGQTRDDAVGEAFDKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLG
ERMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALRERLSATAKPIPVAYPPIWLC
TDNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI
>Mature_353_residues
SQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHILTITPVINTVLAQVPGGWSAI
NAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHLEGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLND
HGDYRLLGQTRDDAVGEAFDKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLGE
RMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALRERLSATAKPIPVAYPPIWLCT
DNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=349, Percent_Identity=31.5186246418338, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI8923380, Length=338, Percent_Identity=28.1065088757396, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=41.812865497076, Blast_Score=250, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17557464, Length=333, Percent_Identity=31.8318318318318, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71995670, Length=347, Percent_Identity=27.0893371757925, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320099, Length=353, Percent_Identity=31.728045325779, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=310, Percent_Identity=25.8064516129032, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=30.8823529411765, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=28.5294117647059, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37712; Mature: 37580

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHI
CCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEE
LTITPVINTVLAQVPGGWSAINAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHL
EEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHEEEECCCCEEEECCC
EGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLNDHGDYRLLGQTRDDAVGEAF
CCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCHHHHHHH
DKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLG
HHHHHHHHCCCCCCCCHHHHHCCCCCCCEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ERMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
ERLSATAKPIPVAYPPIWLCTDNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQQMPAGFTILAIETSCDETAAAVIRDGREIVANSVASQIDIHQRYGGVVPEVASRQHI
CCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHCCCCEE
LTITPVINTVLAQVPGGWSAINAVATTYGPGLAGALLTGINTAKAIAWSRNLPFIGVNHL
EEEHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHEEEECCCCEEEECCC
EGHIYASWLHTAKDLAYQAPEFPCVALIVSGGHTALVLLNDHGDYRLLGQTRDDAVGEAF
CCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCHHHHHHH
DKVARIMGLGYPGGPQMEKVARGVNPGALKLPRAWLRGTYDWSFSGLKTAVLNVVNDRLG
HHHHHHHHCCCCCCCCHHHHHCCCCCCCEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ERMEKVKLAEVDPAFTAQLAAAFQDSAVDVLVQKTVAAAREYKAKTIILAGGVAANTALR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
ERLSATAKPIPVAYPPIWLCTDNAAMIGAAAYYRYQAGVQQDWSLDATPSLKLI
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA