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The map label for this gene is acr1 [H]

Identifier: 159897615

GI number: 159897615

Start: 1243345

End: 1244187

Strand: Reverse

Name: acr1 [H]

Synonym: Haur_1086

Alternate gene names: 159897615

Gene position: 1244187-1243345 (Counterclockwise)

Preceding gene: 159897621

Following gene: 159897613

Centisome position: 19.6

GC content: 48.4

Gene sequence:

>843_bases
ATGCCAAGCCAATCGCCACCAAAAACCGCCTTGATCACCGGAGCGAACTCAGGTATTGGACTCGAACTGACCAAACGGCT
GCTCGGCGAAGGCTGGGCAGTGATTGGTTTAATCCGTTCACAGTTTCCCACGAACGAGCCAATTCTTCAAGCGGCCCAAA
CTGCGGGTAAACTCCGCAGCTATCAAGCCGAAATCAGCGATTTTACTCAGCTTCGTGCGGCCTTACAAACAATTAAACAG
CAAGAAACCAGCCTCGATTTGTTGTTCAACAATGCTGGAAGGGCAACTGAGCAACTAGTTTTTTCGCCGCAAGGGCGCGA
ATTGAGCTTCGAATTGCAGAGCGTCGTGCCGTATATCATCGCCATGGAGCTGAAAGAATTGCTGTTACGCGGCCAGAACA
AAACGATCATTAATACCTCATCGAATGTGCTGTTAGCACTTCGGAAACTGGAGATCGCTCAACTTGAACGACCGCAAAGC
TTCAAAAAGCTCTTTGGGCCATATGCAACATCCAAATTAGCACTTTCGCTCTGGAACCAAGCGCTTGCGCCACAGCTAGA
AAAAGAAGGCATTAAACTCTACAGTGTTTGTCCTGGGGGTAATCGCGGCTCGCTCAAAACCAATAATGGCTTGCCTTGGT
GGCTGCGACCTTTTCATGGCTTGTTGTTTAAACATCCTAGTAATGGCGCTGAACGTTTGTATAACACTGCCTTCAATCAG
CAGCAATTTCCAAGTGGTAGTTTTATCAATAAAGGTAAGCCGACGGCACTTCCCGCAGCGCAGCAAGCCCACGCAGTTTT
GAACAAAGTTCAAGCAATTTATCAGCAGGAGTTTGCACCCTAG

Upstream 100 bases:

>100_bases
TGCATAATTATCTATCGATCACTAGTAAAATTTGACATTCGCTAAAACATCCAGTAAATTTATTTTATAGCGTTCTATAA
AATAAATCAATGGAGCATCT

Downstream 100 bases:

>100_bases
GGATCAGGGGCCAATTTTAACCACGAGTGCTATGAAGATCTATACAATGTAGAACAGTTCATATAATCGACAGCGAATTG
GGTTCCCTCACCCCAACCCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRSYQAEISDFTQLRAALQTIKQ
QETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYIIAMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQS
FKKLFGPYATSKLALSLWNQALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQ
QQFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP

Sequences:

>Translated_280_residues
MPSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRSYQAEISDFTQLRAALQTIKQ
QETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYIIAMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQS
FKKLFGPYATSKLALSLWNQALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQ
QQFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP
>Mature_279_residues
PSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRSYQAEISDFTQLRAALQTIKQQ
ETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYIIAMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQSF
KKLFGPYATSKLALSLWNQALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQQ
QFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190746, Length=288, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI166795268, Length=243, Percent_Identity=27.9835390946502, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=242, Percent_Identity=28.099173553719, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129347, Length=223, Percent_Identity=27.8026905829596, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656154, Length=270, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922628, Length=270, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30894; Mature: 30763

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRS
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YQAEISDFTQLRAALQTIKQQETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYII
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEECCCCCEEEHHHHHHHHHHH
AMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQSFKKLFGPYATSKLALSLWNQ
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHH
ALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQ
HHCCHHHHCCCEEEEECCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
QQFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSQSPPKTALITGANSGIGLELTKRLLGEGWAVIGLIRSQFPTNEPILQAAQTAGKLRS
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YQAEISDFTQLRAALQTIKQQETSLDLLFNNAGRATEQLVFSPQGRELSFELQSVVPYII
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEECCCCCEEEHHHHHHHHHHH
AMELKELLLRGQNKTIINTSSNVLLALRKLEIAQLERPQSFKKLFGPYATSKLALSLWNQ
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHH
ALAPQLEKEGIKLYSVCPGGNRGSLKTNNGLPWWLRPFHGLLFKHPSNGAERLYNTAFNQ
HHCCHHHHCCCEEEEECCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
QQFPSGSFINKGKPTALPAAQQAHAVLNKVQAIYQQEFAP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA