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The map label for this gene is ppnK [H]

Identifier: 159897572

GI number: 159897572

Start: 1190698

End: 1191525

Strand: Reverse

Name: ppnK [H]

Synonym: Haur_1043

Alternate gene names: 159897572

Gene position: 1191525-1190698 (Counterclockwise)

Preceding gene: 159897573

Following gene: 159897570

Centisome position: 18.77

GC content: 52.78

Gene sequence:

>828_bases
ATGCACACAATTGGCGTTTTGTATAATCCGCTTGCGCCTGCAACAGCCCAAGCAGGGGAACGAATTGCGGCTTGGTTGGG
CGAACGAGGGTTAAGTGTGTGGCTTGGCACATCGCAAAGTGCCCGCGATGAGCCAGAAAAAGTCGCGCCATGCCAATTAA
TGTTGGCGCTTGGTGGCGATGGCACAGTACTCCGCGCCGCCCGCATTGGCATTACCTACAATATGCCGATTTTGGGTGTG
GCGATGGGCCACCTGAGTTTTATGGCCGAAGTTACCGAAGAATCGGTCTATGAAGGCTTAGAGGTGTTGCTCAACGGTGG
TGGTTGGTACGATCAACGCACGTTGGTACGAGCACGCGTTTTACGCCAAGGCCAAGAGATTTTTAATGATCTGGCTTTGA
ACGAGGTGTTGTTGTCGCGGCGTGATGTGGCGCGAGTAGTCCATGTTTCGGTTGCCATCGATGATATGCCATTGACGAGC
TATCGTGCTGATGGGGTTTTGGTTTCGACCGCAACTGGCTCAACCGCTTATGCTTTGGCTGCTGGAGGTCCGGTACTCGA
CCCACGCTCCGATTCGTTGTTGTTGGTGACGGTGGCTGGCCACTTAACCAGTTTGCCAGCCCTCGTGCTACCGCCAGATA
CCAAAATTACCTGGACGCTGGCCCGCCATCATCCAACAATTATTAGCCTTGATGGGCAATGGTCGTTTCCAATTGAGCCT
GATGATCTGATTGAGGTCACCCGTGCTCAAGAGATTTGCCGTTTTGCCCATGTTTATCCTCAAGCCCATTTTTATCAATC
GCTCACTCAGCGTTTGCGTCGGCAATAG

Upstream 100 bases:

>100_bases
GAATGGGTAATCAGCCAACAAGCTAAATAGCTAGCAGCGTAGGACAGTGCTCGGTGAGTGTGTTATGATGCAGCGCAGAA
TGGCCACCACAGGAGGCGCT

Downstream 100 bases:

>100_bases
ATTGGTCGCTGGTGAGCCATGTTTGGTAGCGCTGCAACAATAGGCCGCTGGTTTGACGATAATCAGCCCAGCGCGTTTCA
AGCGGATTGAAGGCTTGCTC

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGDGTVLRAARIGITYNMPILGV
AMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARVLRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTS
YRADGVLVSTATGSTAYALAAGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEP
DDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ

Sequences:

>Translated_275_residues
MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGDGTVLRAARIGITYNMPILGV
AMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARVLRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTS
YRADGVLVSTATGSTAYALAAGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEP
DDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ
>Mature_275_residues
MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGDGTVLRAARIGITYNMPILGV
AMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARVLRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTS
YRADGVLVSTATGSTAYALAAGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEP
DDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=281, Percent_Identity=28.8256227758007, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71999610, Length=178, Percent_Identity=32.0224719101124, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320794, Length=213, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325068, Length=175, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30000; Mature: 30000

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGD
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCC
GTVLRAARIGITYNMPILGVAMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARV
CCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
LRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTSYRADGVLVSTATGSTAYALA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEE
AGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEP
CCCCCCCCCCCCEEEEEECCHHHHCCEEEECCCCCEEEEEECCCCEEEEECCCEECCCCC
DDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHTIGVLYNPLAPATAQAGERIAAWLGERGLSVWLGTSQSARDEPEKVAPCQLMLALGGD
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCC
GTVLRAARIGITYNMPILGVAMGHLSFMAEVTEESVYEGLEVLLNGGGWYDQRTLVRARV
CCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
LRQGQEIFNDLALNEVLLSRRDVARVVHVSVAIDDMPLTSYRADGVLVSTATGSTAYALA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEE
AGGPVLDPRSDSLLLVTVAGHLTSLPALVLPPDTKITWTLARHHPTIISLDGQWSFPIEP
CCCCCCCCCCCCEEEEEECCHHHHCCEEEECCCCCEEEEEECCCCEEEEECCCEECCCCC
DDLIEVTRAQEICRFAHVYPQAHFYQSLTQRLRRQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA