Click here to switch to the map view.

The map label for this gene is fadR [H]

Identifier: 159897543

GI number: 159897543

Start: 1158775

End: 1159413

Strand: Direct

Name: fadR [H]

Synonym: Haur_1014

Alternate gene names: 159897543

Gene position: 1158775-1159413 (Clockwise)

Preceding gene: 159897542

Following gene: 159897544

Centisome position: 18.26

GC content: 48.2

Gene sequence:

>639_bases
ATGCCAAGCCTAGAGAAACCAACCAAGCCCGCTGGATCGTTGAAAGAGCGCCAACGCGAAGAACGCGCTCGGCTGATTTT
AGAGGCAGCCCAAACCATTTTGTTGGAGCGCGGCTACCATGAAACTTCAATCGACGATATTGCAGCCCAAGTTGGCATTG
CCAAAGGCACAGTCTATTTGCACTTTCCTAGCAAAGAAGATTTGATGATTGCCCTGGTGGAGCGGCAATTACAAAACTTT
GTGCAAGTGATCGAAGCGGTGGCGGCCAGCACTAGCAGCGCCCGCGAACGCCTAGAAGCAATTTTGCAACGGACGTATGA
TCCAAGCGAAGCTCGTCGGATGCAGATTTTTCTAGAGGTGTTTGGCAGTGCTGATATGCGTTCGCGGTTTGCCGAAAAGC
ATGAACGCACCCAGCCGATTATCGATCATGTGCGCAATTTGCTACGCGAAATTATCGAGCAAGGCAAAGCTCAGGGCGAA
TTTGATCCCAACATCTCAACCAAAGTAATGATTGTGATGTATCTCAATTTGCTTTCTCCTCGCAACTACCATCATCTGAC
AACTGATCAAACAGTGGCGTTTGAAGAGTTGCTGCCTCAAATAATTCAAATTTTCTTCCATGGGATTTCACGGAAGTAG

Upstream 100 bases:

>100_bases
TTTGACTGGATTGACATGGAATAGTGTTAGGGTTATTATTTGACTTATCGGTCATAAATTGTTTGATGGTCAAATAATGG
CTGAGCGTAAGGAATTGAGC

Downstream 100 bases:

>100_bases
GCTTAAGAAAGGCGCGGAATGGAAACGGCAATTAAGCAAGCGGCTTCGGCAGCAGTTGAATTTGAACAGCCACGCTATAC
CAAGCGCGAAACCTTGCTCA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MPSLEKPTKPAGSLKERQREERARLILEAAQTILLERGYHETSIDDIAAQVGIAKGTVYLHFPSKEDLMIALVERQLQNF
VQVIEAVAASTSSARERLEAILQRTYDPSEARRMQIFLEVFGSADMRSRFAEKHERTQPIIDHVRNLLREIIEQGKAQGE
FDPNISTKVMIVMYLNLLSPRNYHHLTTDQTVAFEELLPQIIQIFFHGISRK

Sequences:

>Translated_212_residues
MPSLEKPTKPAGSLKERQREERARLILEAAQTILLERGYHETSIDDIAAQVGIAKGTVYLHFPSKEDLMIALVERQLQNF
VQVIEAVAASTSSARERLEAILQRTYDPSEARRMQIFLEVFGSADMRSRFAEKHERTQPIIDHVRNLLREIIEQGKAQGE
FDPNISTKVMIVMYLNLLSPRNYHHLTTDQTVAFEELLPQIIQIFFHGISRK
>Mature_211_residues
PSLEKPTKPAGSLKERQREERARLILEAAQTILLERGYHETSIDDIAAQVGIAKGTVYLHFPSKEDLMIALVERQLQNFV
QVIEAVAASTSSARERLEAILQRTYDPSEARRMQIFLEVFGSADMRSRFAEKHERTQPIIDHVRNLLREIIEQGKAQGEF
DPNISTKVMIVMYLNLLSPRNYHHLTTDQTVAFEELLPQIIQIFFHGISRK

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24338; Mature: 24207

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLEKPTKPAGSLKERQREERARLILEAAQTILLERGYHETSIDDIAAQVGIAKGTVYL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEE
HFPSKEDLMIALVERQLQNFVQVIEAVAASTSSARERLEAILQRTYDPSEARRMQIFLEV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGSADMRSRFAEKHERTQPIIDHVRNLLREIIEQGKAQGEFDPNISTKVMIVMYLNLLSP
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
RNYHHLTTDQTVAFEELLPQIIQIFFHGISRK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSLEKPTKPAGSLKERQREERARLILEAAQTILLERGYHETSIDDIAAQVGIAKGTVYL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEE
HFPSKEDLMIALVERQLQNFVQVIEAVAASTSSARERLEAILQRTYDPSEARRMQIFLEV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FGSADMRSRFAEKHERTQPIIDHVRNLLREIIEQGKAQGEFDPNISTKVMIVMYLNLLSP
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
RNYHHLTTDQTVAFEELLPQIIQIFFHGISRK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]