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The map label for this gene is tolB [H]

Identifier: 159897506

GI number: 159897506

Start: 1120474

End: 1121424

Strand: Direct

Name: tolB [H]

Synonym: Haur_0977

Alternate gene names: 159897506

Gene position: 1120474-1121424 (Clockwise)

Preceding gene: 159897504

Following gene: 159897508

Centisome position: 17.65

GC content: 48.48

Gene sequence:

>951_bases
ATGAACCTTGTTCGTAGCTTAACATTAATTGGAATACTTGGCTGTTTAACTGGCTGTATGCGTACAACTGCTGAGCCAAC
CAGTCAACCAACGAGCCTGCCATCAAGCGTCCCGCTTGCCACTCCAACCGTGGGCGAAGCCCCGCAACGCTTGGCTTTTG
TTGCCAATCAGATCAACCGAGGAACGATCATGATCTCGGGGCTTGATGCTAACCCACCGCAACTACTCAACCCTGATTTT
CCGCTAGCCATAGATCCAACGTGGTCGCCTGATGGTAACGAACTGGCGTTTGTGGTGCAAGATAGCGATGGCTTCAATAT
GTATATCAGTTCTGCTGATGGCAGTAATTTATTCCAAGTAACCAATCAACCAGGTGACGATCAAAGCCCCAGTTGGTCGC
CTGATGGCCAACAATTGGCGTTTCAATCCAATCGCTCGGGCAATGACGAATTGTATCTGATCAATCGTGATGGCAGTAAT
CTTAGACAACTCACCAACGATCCTGCCCGAGATTGGCAACCAAGTTGGTCGCCTGATGGAAGTTTGATTGCTTTTACTTC
AGATCGTGGGGCGCAAACTCCTGATGGTTGGAATGATCAATTGTATGTAATTCAGCCTGATGGTCAAGGCTTGAAGTATT
TAACCGAAGGCTTTGGCCGCGCTCGCCATCCTGCGTGGTCGCCTGATAGTCAACAGCTTGTCTATGTCGTTGGTGGTGGT
GATGTAGGCAGTAACTCGATTTATACCGTCAATCGCGATGGCAGCGATCCGACGTTGCTGTATGCCAATGCCTTCGACCC
TCAATGGCTTGATCAGCGAATGTTGTTTACCACCTATGATGAGCAAACATTTCATACTGCGCTGCGTATATTGGATTTGA
ATACCTTAGAAGTGAGCGTGCCGATCACAATGGCGGATACAGATCTCATCCAACCAGTTTTGAATCGCTGA

Upstream 100 bases:

>100_bases
AATGGCTGGTTATTAAAAATGAGATCAAGTTGCTGCGATTGTGTAACTGAAATTTGCATAAAGAACCTTTTTCAAATAGT
CGAATCTGTGTGAGGGATCA

Downstream 100 bases:

>100_bases
TCCTGATCGAACGTCGTTTAACCACGTTTTTAGGTAAGAAGGGAAGAATCATATGCAGCCCGTTCGTTGTGCAAGCTGTC
AATCCAATAAAATAATTCCT

Product: WD40 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINRGTIMISGLDANPPQLLNPDF
PLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQVTNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSN
LRQLTNDPARDWQPSWSPDGSLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGG
DVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSVPITMADTDLIQPVLNR

Sequences:

>Translated_316_residues
MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINRGTIMISGLDANPPQLLNPDF
PLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQVTNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSN
LRQLTNDPARDWQPSWSPDGSLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGG
DVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSVPITMADTDLIQPVLNR
>Mature_316_residues
MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINRGTIMISGLDANPPQLLNPDF
PLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQVTNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSN
LRQLTNDPARDWQPSWSPDGSLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGG
DVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSVPITMADTDLIQPVLNR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=167, Percent_Identity=31.7365269461078, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32564217, Length=203, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564215, Length=203, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 34553; Mature: 34553

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GTIMISGLDANPPQLLNPDFPLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQV
CEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEE
TNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSNLRQLTNDPARDWQPSWSPDG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCC
SLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGG
CEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
DVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSV
CCCCCCEEEEECCCCCCEEEEECCCCHHHHCCEEEEEECCCHHHHHEEEEEECCEEEEEE
PITMADTDLIQPVLNR
EEEECCHHHHHHHHCC
>Mature Secondary Structure
MNLVRSLTLIGILGCLTGCMRTTAEPTSQPTSLPSSVPLATPTVGEAPQRLAFVANQINR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GTIMISGLDANPPQLLNPDFPLAIDPTWSPDGNELAFVVQDSDGFNMYISSADGSNLFQV
CEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEE
TNQPGDDQSPSWSPDGQQLAFQSNRSGNDELYLINRDGSNLRQLTNDPARDWQPSWSPDG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCC
SLIAFTSDRGAQTPDGWNDQLYVIQPDGQGLKYLTEGFGRARHPAWSPDSQQLVYVVGGG
CEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
DVGSNSIYTVNRDGSDPTLLYANAFDPQWLDQRMLFTTYDEQTFHTALRILDLNTLEVSV
CCCCCCEEEEECCCCCCEEEEECCCCHHHHCCEEEEEECCCHHHHHEEEEEECCEEEEEE
PITMADTDLIQPVLNR
EEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA