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The map label for this gene is yycG [H]

Identifier: 159897466

GI number: 159897466

Start: 1071452

End: 1073056

Strand: Direct

Name: yycG [H]

Synonym: Haur_0937

Alternate gene names: 159897466

Gene position: 1071452-1073056 (Clockwise)

Preceding gene: 159897464

Following gene: 159897477

Centisome position: 16.88

GC content: 51.15

Gene sequence:

>1605_bases
ATGTTAGAGCCTCAGGATCTGCGATTACGCCAACGTGATTATTTATTGCGTTTGATGCGGGCAATGGCTGCCCAGCTTGA
TGCTGAGCCGTTGCTCAATCTGGTGATCGCCCAAGCAGTCGAGTTGTTGGCGGGTAATTATGGCTTGATCGCCTTGTACA
ATCCCAATCAGCGGCTCGAAATTCGCGCCGCCTATGGGCTTACGCCTAGTTTGTGGTCGGCCTTCGATGAAATTTTGCAT
GTGTTGGAAAGTGAAGGCCCACAATCAAGCCACATGTCGAATGAATTAAGCAGGCTGGCGAATGCGTTGAATGTGCCATT
ACGCCAAGTTGTGGCGTTGCCAATGGTTACTGGCGATCAGCAATTGGGCATGATGTTGGTGTTGCGGGCGGCACTCAACG
TGGGTTTTACTGCTGATGATCGTCAATTGCTCAGCGCATTTGTCGATTTTGCGGCGATTGCGGTCAACAATTCGCAACTC
TACGCCGAAGCAATTGCTGAACGTGGGCGGCTCGATGCCATTATTGAATCAAGCGCCGATGGCATGATGATGCTCGACAC
CCGTTGGCGAATCACCCGCTTCAACGCGGCCATGGAGCGCTTGACTGGTTGGTCGCGTGAAGAGGCTTTGGGGCGACCAT
GCGCCGAAGTGTTGGCAATTCACAATCAGCAAGGAGTCAATATTTGCTTAACTGCCTGTCCGTTGCAACTCTTCCCTGAC
AATGATCATCCTTCGGTTGAGGGTTGGGTGACCCATCGTGATGGTCACGAGATTTATGTTGGCTCATCGTATAGTGTGGT
GCGCGAACCAACTGGCCGTTTTGGTGGGGCAATTGCCAATATTCGCGATATTACCAAGCAAAAACGCGATGAGCAGCAAC
AATCAACCTTTATTTCGGTGATGTCGCATGAATTAAAAACCCCAGTTGCGATTATTAAAGGCTATGCCAGCACGCTTAGT
CGCACCGATGTAAAGCTCAATAAAGCTACTAAAGCCGAAATGTTAACTGGCATCGAAGAGGAAGCTGATCGCTTGGCCCG
CTTGATTGGCGATTTGCTGGAAGTTTCGCGCATGCAGGCGGGTGGCTTGCGGTTGCACCCAGCGCCCTTTGATCTCAGTG
AGTTGGCAGCTGATGTGGTGGCCGCCTTTGCCGCGACGGTTGATCAGCGCTTTGAATTTCAACTGCGTTTCGAGCCAAAA
CTGCCGCATGTCTATGCCGATCAAGAGCGGATTCGCATGGTGCTCTCCAATTTGATTTCAAATGCGATCAAATATTCGCC
AGAAGGTGGCGTGATTCGCTTGGGTGGTTGGCCGGAGAATGGTCATGTGCTCAGTTATGTAACTGACGAAGGCATTGGCA
TCGCCCAAGAGGAACTACCCAAATTGTTTACGCCATTTTATCGGGTTGATAATCGCTTGGCACGTGAAACTCAAGGTGCT
GGCTTGGGTTTGTATCTGACGAAATCGATTATTGAGGCTCATGGTGGCCGCATGTGGGCCGATAGCACGGTGGGAAAAGG
CTCGCGCTTCTATTGGACATTGCCAATTGCCCCGCCCAGCTTGCCAGATGTTGAGCCAAGCATGATTTTGGCCAATGGGG
AATAG

Upstream 100 bases:

>100_bases
TTTTGTTTTTGCTGTCGATGTCGTCTGCATCAATCAATTTCGTAACTGTTTGTATAATACTCTGGCAGTGTTAGAACAAC
ATCTATGGAGCGTTAGAGCC

Downstream 100 bases:

>100_bases
TTAAATTAATCTTGATCAATGTGATCTAAAATGCAAAGGCCGCGTCACTCGACGCGGCCTTGCTTATTTTAGCTGGGAGC
GAGTTTAGCGTATAACGAAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLEIRAAYGLTPSLWSAFDEILH
VLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQQLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQL
YAEAIAERGRLDAIIESSADGMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPD
NDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISVMSHELKTPVAIIKGYASTLS
RTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQAGGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPK
LPHVYADQERIRMVLSNLISNAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGA
GLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE

Sequences:

>Translated_534_residues
MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLEIRAAYGLTPSLWSAFDEILH
VLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQQLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQL
YAEAIAERGRLDAIIESSADGMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPD
NDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISVMSHELKTPVAIIKGYASTLS
RTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQAGGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPK
LPHVYADQERIRMVLSNLISNAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGA
GLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE
>Mature_534_residues
MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLEIRAAYGLTPSLWSAFDEILH
VLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQQLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQL
YAEAIAERGRLDAIIESSADGMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPD
NDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISVMSHELKTPVAIIKGYASTLS
RTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQAGGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPK
LPHVYADQERIRMVLSNLISNAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGA
GLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=29.0760869565217, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=33.1932773109244, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=28.042328042328, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=29.0076335877863, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=30.4721030042918, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=30.8943089430894, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=30.8695652173913, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.1304347826087, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=33.0275229357798, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=30.2904564315353, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=29.0598290598291, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=30.1310043668122, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=27.5555555555556, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790300, Length=365, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=27.8846153846154, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=27.9475982532751, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=24.7863247863248, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=26.4423076923077, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59115; Mature: 59115

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLE
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
IRAAYGLTPSLWSAFDEILHVLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQ
EEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
QLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQLYAEAIAERGRLDAIIESSAD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCHHHHHCCCC
GMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPD
CEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCEEEEEECCEEECCC
NDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISV
CCCCCCCEEEEECCCCEEEECCCCCEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MSHELKTPVAIIKGYASTLSRTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQA
HHHHHHCHHHHHHHHHHHHHHCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
GGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPKLPHVYADQERIRMVLSNLIS
CCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEECCHHHHHHHHHHHHH
NAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGA
HHHEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE
CEEHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MLEPQDLRLRQRDYLLRLMRAMAAQLDAEPLLNLVIAQAVELLAGNYGLIALYNPNQRLE
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
IRAAYGLTPSLWSAFDEILHVLESEGPQSSHMSNELSRLANALNVPLRQVVALPMVTGDQ
EEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
QLGMMLVLRAALNVGFTADDRQLLSAFVDFAAIAVNNSQLYAEAIAERGRLDAIIESSAD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCHHHHHCCCC
GMMMLDTRWRITRFNAAMERLTGWSREEALGRPCAEVLAIHNQQGVNICLTACPLQLFPD
CEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCEEEEEECCEEECCC
NDHPSVEGWVTHRDGHEIYVGSSYSVVREPTGRFGGAIANIRDITKQKRDEQQQSTFISV
CCCCCCCEEEEECCCCEEEECCCCCEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MSHELKTPVAIIKGYASTLSRTDVKLNKATKAEMLTGIEEEADRLARLIGDLLEVSRMQA
HHHHHHCHHHHHHHHHHHHHHCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
GGLRLHPAPFDLSELAADVVAAFAATVDQRFEFQLRFEPKLPHVYADQERIRMVLSNLIS
CCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEECCHHHHHHHHHHHHH
NAIKYSPEGGVIRLGGWPENGHVLSYVTDEGIGIAQEELPKLFTPFYRVDNRLARETQGA
HHHEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GLGLYLTKSIIEAHGGRMWADSTVGKGSRFYWTLPIAPPSLPDVEPSMILANGE
CEEHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]