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The map label for this gene is coaD

Identifier: 159897269

GI number: 159897269

Start: 847005

End: 847502

Strand: Direct

Name: coaD

Synonym: Haur_0740

Alternate gene names: 159897269

Gene position: 847005-847502 (Clockwise)

Preceding gene: 159897268

Following gene: 159897270

Centisome position: 13.35

GC content: 50.2

Gene sequence:

>498_bases
GTGACTATTGCTGTCTACCCTGCAAGCTTCGACCCAATTACCAATGGACATCTTGATGTTGCGGCTCGCGCATCACGTTT
GTTCGATGAATTGGTCTTAGCGGTAGCTCATCGTCCGTACAAAAAGTTGCTTTTTACGACTGAGCAACGGATTGCCATGA
TTCGCGAATCGGTAGCGCACCTGCCCAATGTGCGGGTGGATGCTTTTTCGAGTTTAGTTGTGGAGTATGCGCTTGAGATT
GGTGCAACCGTGTTGGTACGAGGCTTACGGGCTGCAACCGATTTTGAGCACGAATTTCAAATGGCGCATATCAATCATCA
CTTAGCTCCCACGCTTGATACGGTCTGTTTGATGGCTGATCAACGCTTTACGTTGCTTAGCTCAAGCGCGGTACGCGAAA
TTGCGGCCTATGGCGGCGATGTTAGCTCTTTTGTGCCAGCTCATATTGCCCTTGCGCTCAAGCAAGCCTATCAAACGCAT
GAGGAGTCACGCGCATGA

Upstream 100 bases:

>100_bases
TGGGCCACTGAGTTTGCTAAAGCATCGGCGTATCGGCGATTCCTGCTTCTCAATTTATGAATTGAGCCCAGCGTTACCGC
CGCAATCGGAGTAATCACCT

Downstream 100 bases:

>100_bases
GCGAACAATCCCAATGGGGAGAACAGCCCAGTGAACATCAGGAAGCAACCAGCGTGGAGCCAGTCGGGCAACACCAGCGC
CCCCCAGAATATGCTGAGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAHLPNVRVDAFSSLVVEYALEI
GATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMADQRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTH
EESRA

Sequences:

>Translated_165_residues
MTIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAHLPNVRVDAFSSLVVEYALEI
GATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMADQRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTH
EESRA
>Mature_164_residues
TIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAHLPNVRVDAFSSLVVEYALEIG
ATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMADQRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTHE
ESRA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=150, Percent_Identity=49.3333333333333, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_HERA2 (A9AWY7)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001543516.1
- ProteinModelPortal:   A9AWY7
- SMR:   A9AWY7
- GeneID:   5732463
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_0740
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   HAUR316274:HAUR_0740-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18214; Mature: 18083

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAH
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LPNVRVDAFSSLVVEYALEIGATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTHEESRA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIAVYPASFDPITNGHLDVAARASRLFDELVLAVAHRPYKKLLFTTEQRIAMIRESVAH
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LPNVRVDAFSSLVVEYALEIGATVLVRGLRAATDFEHEFQMAHINHHLAPTLDTVCLMAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRFTLLSSSAVREIAAYGGDVSSFVPAHIALALKQAYQTHEESRA
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA