Click here to switch to the map view.

The map label for this gene is ccdA [H]

Identifier: 159046483

GI number: 159046483

Start: 12980

End: 13702

Strand: Direct

Name: ccdA [H]

Synonym: Dshi_3944

Alternate gene names: 159046483

Gene position: 12980-13702 (Clockwise)

Preceding gene: 159046481

Following gene: 159046484

Centisome position: 10.28

GC content: 62.38

Gene sequence:

>723_bases
TTGGCGCGCGCCCTCACCGCCGCCCTCCTAGCCGGCACGATATCATTTCTGTCCCCCTGCGTGCTACCTCTTGTGCCAGG
TTATGTCTCCTACGTAACCGGGCGCACAGCCGCTGAGGGCGGGGTGGTCGGCGCTTCGCCGTCGCGCGCGGTCTGGCTGA
GCCTGTGTTTTGTCCTCGGCTTCTCCACCATCTTCATGGGACTTGGCGCATCCGCGACTGCAATGGGTCAGGCCCTGCTT
CGGTGGCGGTATGAACTCAACCTCGTTGGGGGCGGCATCATCATTTTCTTCGGGCTCTTCATGATAGGAGCCGCGCGTGT
TTCGGTCATGGAACGCGACTTCCGATTCAATCTCAACATCCCCGGGGGCCAACCCGCTGCGTCCTATGTCCTCGGTCTTG
CCTTCGGTTTCGGCTGGACTCCGTGCATCGGCCCGATCCTCGGCGCGATCCTGACAGCCAGTGCGGCGAGTGCCACGATG
GGCGAAGGTATCATGCTGCTTGCCGTCTATTCCGCCGGCCTTGGAATACCGTTTCTGATCGTGGCCGGATTCACCGACCA
GATCGCGGGACGGTTGCGGGCCATCGGCCGGGTTGGCCGCCGCCTCCACCAGCTTGCGGGCATAGTGATGATCTTGATGG
GGCTGGCGATGATGACAGGGCAGTTGAGCGCGCTGTCATACTGGATGCTCGACGTATTTCCGGTTCTGGGACGGATCGGA
TAG

Upstream 100 bases:

>100_bases
ACCCATCTCCCGCCCGCTATCGTACGACCAACTGGTCCAGCTACAACGCATCGCTGCGCAAGCGGGGGTCCCTGCTGATC
TGGGTCGACGAAGACATCAC

Downstream 100 bases:

>100_bases
CTCCATTAGTAGCAGCGTCTATTGATAACAGAAAATTTTCTTGAACCTCTAGTAGCTTTAGGAGTTAAGCCACCGACAAA
GAACGGCACCATGGAGCAAG

Product: cytochrome c biogenesis protein transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MARALTAALLAGTISFLSPCVLPLVPGYVSYVTGRTAAEGGVVGASPSRAVWLSLCFVLGFSTIFMGLGASATAMGQALL
RWRYELNLVGGGIIIFFGLFMIGAARVSVMERDFRFNLNIPGGQPAASYVLGLAFGFGWTPCIGPILGAILTASAASATM
GEGIMLLAVYSAGLGIPFLIVAGFTDQIAGRLRAIGRVGRRLHQLAGIVMILMGLAMMTGQLSALSYWMLDVFPVLGRIG

Sequences:

>Translated_240_residues
MARALTAALLAGTISFLSPCVLPLVPGYVSYVTGRTAAEGGVVGASPSRAVWLSLCFVLGFSTIFMGLGASATAMGQALL
RWRYELNLVGGGIIIFFGLFMIGAARVSVMERDFRFNLNIPGGQPAASYVLGLAFGFGWTPCIGPILGAILTASAASATM
GEGIMLLAVYSAGLGIPFLIVAGFTDQIAGRLRAIGRVGRRLHQLAGIVMILMGLAMMTGQLSALSYWMLDVFPVLGRIG
>Mature_239_residues
ARALTAALLAGTISFLSPCVLPLVPGYVSYVTGRTAAEGGVVGASPSRAVWLSLCFVLGFSTIFMGLGASATAMGQALLR
WRYELNLVGGGIIIFFGLFMIGAARVSVMERDFRFNLNIPGGQPAASYVLGLAFGFGWTPCIGPILGAILTASAASATMG
EGIMLLAVYSAGLGIPFLIVAGFTDQIAGRLRAIGRVGRRLHQLAGIVMILMGLAMMTGQLSALSYWMLDVFPVLGRIG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 25000; Mature: 24869

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARALTAALLAGTISFLSPCVLPLVPGYVSYVTGRTAAEGGVVGASPSRAVWLSLCFVLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FSTIFMGLGASATAMGQALLRWRYELNLVGGGIIIFFGLFMIGAARVSVMERDFRFNLNI
HHHHHHHCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
PGGQPAASYVLGLAFGFGWTPCIGPILGAILTASAASATMGEGIMLLAVYSAGLGIPFLI
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
VAGFTDQIAGRLRAIGRVGRRLHQLAGIVMILMGLAMMTGQLSALSYWMLDVFPVLGRIG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARALTAALLAGTISFLSPCVLPLVPGYVSYVTGRTAAEGGVVGASPSRAVWLSLCFVLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FSTIFMGLGASATAMGQALLRWRYELNLVGGGIIIFFGLFMIGAARVSVMERDFRFNLNI
HHHHHHHCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
PGGQPAASYVLGLAFGFGWTPCIGPILGAILTASAASATMGEGIMLLAVYSAGLGIPFLI
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
VAGFTDQIAGRLRAIGRVGRRLHQLAGIVMILMGLAMMTGQLSALSYWMLDVFPVLGRIG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]