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The map label for this gene is tatD [H]

Identifier: 158423802

GI number: 158423802

Start: 2495238

End: 2496017

Strand: Direct

Name: tatD [H]

Synonym: AZC_2178

Alternate gene names: 158423802

Gene position: 2495238-2496017 (Clockwise)

Preceding gene: 158423799

Following gene: 158423803

Centisome position: 46.47

GC content: 66.41

Gene sequence:

>780_bases
ATGCTCGTCGACAGCCACTGCCACCTCGACTTTCCCGATTTCGCCGCCGAACTGCCCGATGTGGTGGCGCGCGCCAAGGC
GGCGGGGGTGTCGCACCTCGTGACCATTTCGACGCGGGTGAGGCGTTTTCCGGAAATCCTCGCCATTGCCGAGCGCTTTG
ACGAGGTGAGCTGCTCGGTGGGCACCCATCCCCATCAGGCGGCGGAGGAACTGGACATCACCACCGCCGATCTGGTGCGG
TTGTCCGCCCATCCCAAGGTGGTGGCGATCGGCGAGGTGGGGCTGGATTATCATTACGACAACAGCCCCCGCGAGGCGCA
GGCGCACGGCTTCCACACCCACATCGCCGCCGCGCGCGAGACCGGCCTGCCGCTGGTGATCCATGCCCGCGAGGCGGATG
ATGACGTGGCCGAGATCCTGGAGACTGAAAGCGCCAAGGGCGCCTTTCCCTTCCTGCTGCATTGCTACACGGGTGGGGCT
GATCTGGCGCACCGCGCGGTGAAGCTGGGCGGCTATGTGTCCTTCTCGGGCGTCATCACCTTCAAGAAGAGCGAGGACCT
GCGTGCGCTCGCGGCCAGTCTGCCGCAGGACCGGCTGCTGGTGGAGACGGACGCGCCCTTCCTCGCGCCGACGCCCCATC
GCGGCAAGCGCAACGAGCCGGCCTTCGTGCGCAACACGGCGATGGTGCTGGCGGAAACGCTTGGCGTGAGCCTTGAGGAG
ATCGGCGCCGTCACCACGGAGAATTTCTACAGGCTGTTCTCCAAGGCGCGGCGGACATAA

Upstream 100 bases:

>100_bases
GCACGAGGCAAGCACAAAGCACTGCGCGGCTCGACGGACGTCCCCCCAGCGCTTATGTGAGGCGCACGTGCCTCGCCCCA
CCAGAGTTGCCTGATCCGTT

Downstream 100 bases:

>100_bases
GCCTCGCAAGCGTCGACGTCCCCGCGCCAAAAGGACAAGAACCGGAGGAAATGCGCTTGGACCACGATCATTATGCGGAC
GCCTACATCCGGGGGATCCT

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLVDSHCHLDFPDFAAELPDVVARAKAAGVSHLVTISTRVRRFPEILAIAERFDEVSCSVGTHPHQAAEELDITTADLVR
LSAHPKVVAIGEVGLDYHYDNSPREAQAHGFHTHIAAARETGLPLVIHAREADDDVAEILETESAKGAFPFLLHCYTGGA
DLAHRAVKLGGYVSFSGVITFKKSEDLRALAASLPQDRLLVETDAPFLAPTPHRGKRNEPAFVRNTAMVLAETLGVSLEE
IGAVTTENFYRLFSKARRT

Sequences:

>Translated_259_residues
MLVDSHCHLDFPDFAAELPDVVARAKAAGVSHLVTISTRVRRFPEILAIAERFDEVSCSVGTHPHQAAEELDITTADLVR
LSAHPKVVAIGEVGLDYHYDNSPREAQAHGFHTHIAAARETGLPLVIHAREADDDVAEILETESAKGAFPFLLHCYTGGA
DLAHRAVKLGGYVSFSGVITFKKSEDLRALAASLPQDRLLVETDAPFLAPTPHRGKRNEPAFVRNTAMVLAETLGVSLEE
IGAVTTENFYRLFSKARRT
>Mature_259_residues
MLVDSHCHLDFPDFAAELPDVVARAKAAGVSHLVTISTRVRRFPEILAIAERFDEVSCSVGTHPHQAAEELDITTADLVR
LSAHPKVVAIGEVGLDYHYDNSPREAQAHGFHTHIAAARETGLPLVIHAREADDDVAEILETESAKGAFPFLLHCYTGGA
DLAHRAVKLGGYVSFSGVITFKKSEDLRALAASLPQDRLLVETDAPFLAPTPHRGKRNEPAFVRNTAMVLAETLGVSLEE
IGAVTTENFYRLFSKARRT

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=273, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=32.967032967033, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI226061853, Length=281, Percent_Identity=32.7402135231317, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=32.5581395348837, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI225903424, Length=274, Percent_Identity=29.5620437956204, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=31.6239316239316, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI14042943, Length=209, Percent_Identity=26.7942583732057, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI225903439, Length=167, Percent_Identity=28.1437125748503, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=42.1875, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=30.9803921568627, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=32.4427480916031, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=29.0780141843972, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=29.6992481203008, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=303, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=215, Percent_Identity=29.7674418604651, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=30.0353356890459, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI221330018, Length=206, Percent_Identity=29.6116504854369, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24586117, Length=206, Percent_Identity=29.6116504854369, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28210; Mature: 28210

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDFAAELPDVVARAKAAGVSHLVTISTRVRRFPEILAIAERFDEVSCSV
CEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GTHPHQAAEELDITTADLVRLSAHPKVVAIGEVGLDYHYDNSPREAQAHGFHTHIAAARE
CCCCHHHHHHCCCCHHHHHEECCCCCEEEEECCCCEECCCCCCCCHHHCCCHHHHHHHHH
TGLPLVIHAREADDDVAEILETESAKGAFPFLLHCYTGGADLAHRAVKLGGYVSFSGVIT
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEEEE
FKKSEDLRALAASLPQDRLLVETDAPFLAPTPHRGKRNEPAFVRNTAMVLAETLGVSLEE
EECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IGAVTTENFYRLFSKARRT
HCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVDSHCHLDFPDFAAELPDVVARAKAAGVSHLVTISTRVRRFPEILAIAERFDEVSCSV
CEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCC
GTHPHQAAEELDITTADLVRLSAHPKVVAIGEVGLDYHYDNSPREAQAHGFHTHIAAARE
CCCCHHHHHHCCCCHHHHHEECCCCCEEEEECCCCEECCCCCCCCHHHCCCHHHHHHHHH
TGLPLVIHAREADDDVAEILETESAKGAFPFLLHCYTGGADLAHRAVKLGGYVSFSGVIT
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEEEE
FKKSEDLRALAASLPQDRLLVETDAPFLAPTPHRGKRNEPAFVRNTAMVLAETLGVSLEE
EECCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IGAVTTENFYRLFSKARRT
HCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]