Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 158423671

GI number: 158423671

Start: 2360298

End: 2361137

Strand: Direct

Name: appC [H]

Synonym: AZC_2047

Alternate gene names: 158423671

Gene position: 2360298-2361137 (Clockwise)

Preceding gene: 158423670

Following gene: 158423672

Centisome position: 43.96

GC content: 68.1

Gene sequence:

>840_bases
ATGAAGGGCTTCTGGTCCCGCTTCTGCCGGCACAAGGCTGCCGTCGCCGGGCTTGTCGTGGTGGTGCTGCTGGTCGCCGT
CGCGCTCGCCGCGCCCTATCTCTATCCCGCTTCGCCCTGGAAGATGGTCCAGCGGCCCTTCCTCGCGCCCTTCGTGAACG
CCGCCGTGCCCCTGGGCACGGATACGCTCGGCCGCAATGTGGCGAGCGGCCTCGTGCACGGGGCGCGCGTCTCGCTGCTC
ATCGGTACGGTCTCGACGCTGGTGGCCCTCGTGATCGGCGTGCCGATCGGCGCCATCGCCGGCTATTTCGGCGGGATCGT
GGATGACCTGCTGATGCGCGTCACCGAATTCTTCCAGACGGTGCCGAGTTTTGCGCTGGCCATCGTCCTTGTGGCGATCT
TCCAGCCGAGCCTCGTTTCCATCGTGACTGCCATCGGCATCGTCGGCTGGCCGCCGGTGGCGCGGCTGGTACGCGGCGAG
GTGCTGGCCCAGCGCAAGCGCGAATATGTGGAAGCGGCGATCCTCTGCGGACAGTCGCATTTCACCATCATCACCCGCCA
GATTCTGCCCAACGTGGTCTCGCCCATCGTGGTGCTGGCCTCGCTGATGGTGGCGACCGCCATCCTGCTGGAAAGCTCGC
TCTCCTTCCTCGGCCTCGGCGACCCGTCCGTCATGTCGTGGGGCTACATGGTGGGCGCGGCGCGCACGGTGGTGCGGCAG
GCCTGGTGGCTCTCCGTCCTGCCGGGCCTCGCCATCGTGATCGCCGTGCTCGCCATCAATCTGGTGGGCGAGGGGCTGTC
GGAAGCGCTCGACCCGCGTTCGGCCCGCGACCATGCGTGA

Upstream 100 bases:

>100_bases
TGCTCGGCGTCTTCGTGGTCTCTGCCGCCATGGTGGTGGTGTTCAACATCCTGACCGATCTCGTCTACCGCATGGTGGAC
CCGCGCATCGAGGTGTCGCG

Downstream 100 bases:

>100_bases
GGAGCGCGCCATGAGCGAACAGCCCATCCTCTCCGTCTCCGGCCTTGCCATCCAGTTGCCGGCGGGTGCCGACCGGCTCT
ACGCGGTGGAGCATGTCAGC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKGFWSRFCRHKAAVAGLVVVVLLVAVALAAPYLYPASPWKMVQRPFLAPFVNAAVPLGTDTLGRNVASGLVHGARVSLL
IGTVSTLVALVIGVPIGAIAGYFGGIVDDLLMRVTEFFQTVPSFALAIVLVAIFQPSLVSIVTAIGIVGWPPVARLVRGE
VLAQRKREYVEAAILCGQSHFTIITRQILPNVVSPIVVLASLMVATAILLESSLSFLGLGDPSVMSWGYMVGAARTVVRQ
AWWLSVLPGLAIVIAVLAINLVGEGLSEALDPRSARDHA

Sequences:

>Translated_279_residues
MKGFWSRFCRHKAAVAGLVVVVLLVAVALAAPYLYPASPWKMVQRPFLAPFVNAAVPLGTDTLGRNVASGLVHGARVSLL
IGTVSTLVALVIGVPIGAIAGYFGGIVDDLLMRVTEFFQTVPSFALAIVLVAIFQPSLVSIVTAIGIVGWPPVARLVRGE
VLAQRKREYVEAAILCGQSHFTIITRQILPNVVSPIVVLASLMVATAILLESSLSFLGLGDPSVMSWGYMVGAARTVVRQ
AWWLSVLPGLAIVIAVLAINLVGEGLSEALDPRSARDHA
>Mature_279_residues
MKGFWSRFCRHKAAVAGLVVVVLLVAVALAAPYLYPASPWKMVQRPFLAPFVNAAVPLGTDTLGRNVASGLVHGARVSLL
IGTVSTLVALVIGVPIGAIAGYFGGIVDDLLMRVTEFFQTVPSFALAIVLVAIFQPSLVSIVTAIGIVGWPPVARLVRGE
VLAQRKREYVEAAILCGQSHFTIITRQILPNVVSPIVVLASLMVATAILLESSLSFLGLGDPSVMSWGYMVGAARTVVRQ
AWWLSVLPGLAIVIAVLAINLVGEGLSEALDPRSARDHA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=271, Percent_Identity=36.90036900369, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789964, Length=279, Percent_Identity=41.9354838709677, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=38.0952380952381, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=35.5805243445693, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789889, Length=232, Percent_Identity=37.0689655172414, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788505, Length=237, Percent_Identity=32.0675105485232, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787549, Length=276, Percent_Identity=31.5217391304348, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29495; Mature: 29495

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKGFWSRFCRHKAAVAGLVVVVLLVAVALAAPYLYPASPWKMVQRPFLAPFVNAAVPLGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
DTLGRNVASGLVHGARVSLLIGTVSTLVALVIGVPIGAIAGYFGGIVDDLLMRVTEFFQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VPSFALAIVLVAIFQPSLVSIVTAIGIVGWPPVARLVRGEVLAQRKREYVEAAILCGQSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FTIITRQILPNVVSPIVVLASLMVATAILLESSLSFLGLGDPSVMSWGYMVGAARTVVRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AWWLSVLPGLAIVIAVLAINLVGEGLSEALDPRSARDHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]