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The map label for this gene is lepB [H]

Identifier: 158423627

GI number: 158423627

Start: 2309725

End: 2310477

Strand: Direct

Name: lepB [H]

Synonym: AZC_2003

Alternate gene names: 158423627

Gene position: 2309725-2310477 (Clockwise)

Preceding gene: 158423626

Following gene: 158423628

Centisome position: 43.01

GC content: 62.02

Gene sequence:

>753_bases
ATGACTGCGACCAGTGATTCCAAGAAGGACGGCGGATTTCTCGAGACCGTCCGCGTCATCGTCCATGCGCTCCTGATCGC
ATTGGTGATCCGCACCCTGCTGTTCCAGCCCTTCAACATCCCTTCGGGGTCCATGAAGGATACGCTGCTGATTGGCGACT
ATCTGTTCGTCTCCAAGTACAGCTACGGCTATTCGCGCTTCTCCCTGCCGCTCTCCCCGCCGCTCTTCACCGGCCGCATC
TGGGGCAAGGAGCCGACCCGCGGCGACGTGGTGGTGTTCAAGCTGCCGAAGGACGGCGAGACGGACTATATCAAGCGCCT
AGTCGGCATGCCGGGCGACGACATCCAGATGATCGACGGCGTGCTGCACATCAATGGCGTGCCGGTGAAGCGCGAGCGCC
TGTCCGACGTGATGGAGGATGACGGCACCGGCCGTCAGGCGCCGGTGAAGCGCTGGCGCGAAACGCTGCCGAACGGCGTC
TCCTACGAGACGCTCGATATCGTGGACAACGGCTTCTACGACAACACGCCCGTCTATCACGTGCCGGCCGGCCATTTCTT
CATGATGGGCGATAACCGGGACAATTCCGCCGACAGCCGCGTGCTGAGCCAGGTGGGCTATGTGCCGTTCGAGAATCTGG
TGGGGAAGGCGCAGATGATCTTCTTCTCCATCGATGAGCACACCCCGGCCTGGCAGGTGTGGAACTGGCCCTGGACCGTG
CGTTGGACCCGCATCTTCAGCATGGTGCGATGA

Upstream 100 bases:

>100_bases
CCGTGCGTGCGCATGGCATTGCCGCTGGGTCAAGACTTTCGACCCGTTTTCGGCACAGTTTGCTGCACACTGGCGCGGAC
TTTATTGCACCGGATCCTCA

Downstream 100 bases:

>100_bases
GCGAGACGCAGGATTTCGCCGCGCTGGAGGCGCGGCTCGGGCACAGCTTCGCCGACCGCAGCCATCTCGTGCTCGCGCTG
ACTCATATCAGCTCGGTTAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSLPLSPPLFTGRI
WGKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDGVLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGV
SYETLDIVDNGFYDNTPVYHVPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTV
RWTRIFSMVR

Sequences:

>Translated_250_residues
MTATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSLPLSPPLFTGRI
WGKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDGVLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGV
SYETLDIVDNGFYDNTPVYHVPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTV
RWTRIFSMVR
>Mature_249_residues
TATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSLPLSPPLFTGRIW
GKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDGVLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGVS
YETLDIVDNGFYDNTPVYHVPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTVR
WTRIFSMVR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=277, Percent_Identity=36.4620938628159, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28442; Mature: 28311

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECC
SYGYSRFSLPLSPPLFTGRIWGKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDG
CCCCEEEECCCCCCCEECEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHCC
VLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGVSYETLDIVDNGFYDNTPVYH
EEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEE
VPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTV
ECCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCEEEECCCEEE
RWTRIFSMVR
HHHHHHHHCC
>Mature Secondary Structure 
TATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECC
SYGYSRFSLPLSPPLFTGRIWGKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDG
CCCCEEEECCCCCCCEECEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHCC
VLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGVSYETLDIVDNGFYDNTPVYH
EEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEE
VPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTV
ECCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCEEEECCCEEE
RWTRIFSMVR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA