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The map label for this gene is acpS

Identifier: 158423626

GI number: 158423626

Start: 2309102

End: 2309512

Strand: Direct

Name: acpS

Synonym: AZC_2002

Alternate gene names: 158423626

Gene position: 2309102-2309512 (Clockwise)

Preceding gene: 158423625

Following gene: 158423627

Centisome position: 43.0

GC content: 69.34

Gene sequence:

>411_bases
ATGATTCTCGGCATCGGCTCCGATTTCTGCGACGCCCGACGTATCGAGAAGTCCATCGAGCGGTTCGGCGCCCGCTTCAC
CGAGCGCGTCTTCACGCCGCTCGAACGGGCGAAGGCCGAACGCCGGGCGCGTCCTGCCGAGACCTATGCGAAGCGCTTCG
CCGCCAAGGAGGCCTGCGCCAAGGCGCTCGGCACGGGCATCGCCCGCGGCGTATTCTGGCGCGACATGGGCGTCGTCAAC
CTGCCCTCGGGCCAGCCGACGCTGGAACTGACCGGCGGCGCGGCGGCGCGGCTGAAGGAAATGGTGCCAGAGGGCTATGA
GCCCCGGATCGCCCTGTCCCTCACCGACGAGGGGCCGCTGTCGGCGGCTTATGTCATCATCAGCGCGGAGCTGATCGGCA
CGCCGCGCTGA

Upstream 100 bases:

>100_bases
ATTTCATGATTGGCGAAGCCATTTTCGAGGGTCTGCCGGGGGTGGTCAGCCTCATGCGGGAAGCCATGGCCCGCGGCCAG
GACCGGCGGGAGCTTGCCGC

Downstream 100 bases:

>100_bases
GGCTCCGAGGGCTTCTTCCCGAGAGGCAGCACACGCAAATGCGTCCGGACTGGAACGGCCCGGCACGGCGCCGCGTTGCC
GCCTGAGCGCGAAACGGTTA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACAKALGTGIARGVFWRDMGVVN
LPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPLSAAYVIISAELIGTPR

Sequences:

>Translated_136_residues
MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACAKALGTGIARGVFWRDMGVVN
LPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPLSAAYVIISAELIGTPR
>Mature_136_residues
MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACAKALGTGIARGVFWRDMGVVN
LPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPLSAAYVIISAELIGTPR

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.0625, Blast_Score=73, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_AZOC5 (A8I3B0)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524918.1
- ProteinModelPortal:   A8I3B0
- SMR:   A8I3B0
- GeneID:   5690138
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2002
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   ACAU438753:AZC_2002-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14799; Mature: 14799

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KALGTGIARGVFWRDMGVVNLPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPL
HHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCC
SAAYVIISAELIGTPR
HHHHHEEEHHHHCCCC
>Mature Secondary Structure
MILGIGSDFCDARRIEKSIERFGARFTERVFTPLERAKAERRARPAETYAKRFAAKEACA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KALGTGIARGVFWRDMGVVNLPSGQPTLELTGGAAARLKEMVPEGYEPRIALSLTDEGPL
HHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCC
SAAYVIISAELIGTPR
HHHHHEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA