Click here to switch to the map view.

The map label for this gene is hipO [H]

Identifier: 158423611

GI number: 158423611

Start: 2291039

End: 2292199

Strand: Direct

Name: hipO [H]

Synonym: AZC_1987

Alternate gene names: 158423611

Gene position: 2291039-2292199 (Clockwise)

Preceding gene: 158423605

Following gene: 158423617

Centisome position: 42.67

GC content: 68.56

Gene sequence:

>1161_bases
ATGCCCGTCGTCAACCGGATCGCCGACCTCGCCGATGAAATCACGGCCTGGCGGCGGGATCTGCATGCCCATCCCGAGCT
GCTCTACGATCTGCCCCGCACCTCGGCGCTGGTGGCCGAACGGTTGACGGCGTTCGGCTGCGATGAGGTGGTGCGCGGCA
TCGGCGGCAGCGGTGTCGTTGGCCTCATCCGGGGCAAGGGGCCCGGTCGCACCATCGCGCTGCGGGCCGACATGGACGCG
CTGCCGCTGACCGAGATCACCGGCGCGCCCTATGCCTCTACGACCCCCGGCAAGATGCACGCCTGCGGCCATGACGGACA
CACCGCCATGCTGCTCGGGGCCGCCAAGATCCTCGCCGAGACGCGCAATTTCTCCGGCACCGTCGCCCTCGTGTTCCAGC
CCGCCGAAGAGGGTGGGGCGGGTGCCAAGGCGATGATCGATGATGGCCTTTTCGAGCGCTTCGGCATCGAGGAGATCTAC
GGCATGCACAACATGCCCGGCATCGCGCTCGGCGCCTTCGGCATGTGCCACGGGCCGATCATGGCCGCCGCCGACGTGAT
CCATATCGACATCGAGGGCCGGGGTGCCCACGCCGCCCAGCCCCATGACGGCGTGGATCCGGTGCTGGTCGGCAGCCACA
TCGTGCTCGCCGCCCAGTCGCTGGTTTCCCGCACCATTGATCCGCTGAAGTCGGCGGTGGTGTCGATTACCCAGTTCAAT
GCCGGCACCACGGACAACATCATTCCGCAGACGGCCCATCTGTGCGGCACCGTGCGCACCTACGATCCGGAGGTGCGCGA
CCTGATCGAAAGCCGGCTCGCCCAGATCGCGGAGACCACCGCCGCCGTCTTCGGGGCCAAGGCGACGCTGCGCTATGTGC
GCGGCTATCCGGCCACCCGCAACCACCCCGCCCAGACGGATTTCGCCGCGCGGGTGGCGAGCGACGTGGCGGGGCCGGCG
GCAGTCGACACGGCCATGCCGCCGCGCATGGGGGCGGAGGATTTTTCCTTCTTCCTGGAGCAGCGCCCCGGCGCCTTCGT
CTTCATCGGCAATGGCGACACGGCCGGCCTGCACAATCCCGCCTATGACTTCGATGACCGGGCCATCGCCAATGGCACCA
GCTATTGGGTGCGGCTGGTGGAGATGGGCCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
CCGTGCCCAACTGTGCGGCAGGATGGCTTGACGGCGCGCGCCCGCTTGGCTTTGGTTGGGCTCTTCCGGCGCTCGTGCGC
GCCCCGCGGAGTTCTCCTTC

Downstream 100 bases:

>100_bases
GGCTCGCCCGGATTGGTCGGTCCCTCACGCGGCATCCGCCCCCAGCGCCCGCCGGACGATGTCGTCCCGCCCGATGGCCG
AGAGCCAGTGGCGGGCGATG

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MPVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVVGLIRGKGPGRTIALRADMDA
LPLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAETRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIY
GMHNMPGIALGAFGMCHGPIMAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFN
AGTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATRNHPAQTDFAARVASDVAGPA
AVDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNPAYDFDDRAIANGTSYWVRLVEMGLPA

Sequences:

>Translated_386_residues
MPVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVVGLIRGKGPGRTIALRADMDA
LPLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAETRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIY
GMHNMPGIALGAFGMCHGPIMAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFN
AGTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATRNHPAQTDFAARVASDVAGPA
AVDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNPAYDFDDRAIANGTSYWVRLVEMGLPA
>Mature_385_residues
PVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVVGLIRGKGPGRTIALRADMDAL
PLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAETRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIYG
MHNMPGIALGAFGMCHGPIMAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFNA
GTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATRNHPAQTDFAARVASDVAGPAA
VDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNPAYDFDDRAIANGTSYWVRLVEMGLPA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=423, Percent_Identity=28.6052009456265, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 40756; Mature: 40625

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCEE
GLIRGKGPGRTIALRADMDALPLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAE
EEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
TRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIYGMHNMPGIALGAFGMCHGPI
HCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHCCHH
MAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFN
HHCCEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATR
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NHPAQTDFAARVASDVAGPAAVDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNP
CCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
AYDFDDRAIANGTSYWVRLVEMGLPA
CCCCCCCHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCEE
GLIRGKGPGRTIALRADMDALPLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAE
EEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
TRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIYGMHNMPGIALGAFGMCHGPI
HCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHCCHH
MAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFN
HHCCEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATR
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NHPAQTDFAARVASDVAGPAAVDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNP
CCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
AYDFDDRAIANGTSYWVRLVEMGLPA
CCCCCCCHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]