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The map label for this gene is dctM [H]

Identifier: 158423521

GI number: 158423521

Start: 2173498

End: 2175369

Strand: Direct

Name: dctM [H]

Synonym: AZC_1897

Alternate gene names: 158423521

Gene position: 2173498-2175369 (Clockwise)

Preceding gene: 158423520

Following gene: 158423529

Centisome position: 40.48

GC content: 67.79

Gene sequence:

>1872_bases
ATGAGCACGGTGTCCCACTCCCAAGACACCGCCTGGGAGGCGGCGGCCCCGGCGTGGGTCGCGGATGCGGAGCGCTGGCT
GCGCCGCATCGTCGAAATCCCTGCCGCCCTGCTGGTGGCCGCCGAGGTGCTTATCCTTTTCGTCGGCATCTGCGCCCGCT
CGTTCCACCGTCCGATCATCTGGTCGGACGAGCTGGCCTCCATCCTCTTCCTCTGGCTCGGGATGCTGGGGGCGGTGGTC
GCCATCCAGCGCGGCGAGCACATGCGCCTCACCTTCCTGGTGAGCATGTTCTCGCGCCGGGCGCAGGCCTGGTGTGAAAC
GCTGGCCGTGGGTGGCGTGTTCGTGCTGCTGGGGCTGCTGATGCACGCGGCCTATGACTACACGCTCGATCAGTCCTTTG
TGGAAATGCCGGCCCTCGGCTGGTCCGGCATGGTGCGGGCGCTCGCCGTGCCGGTGGGCTTTACGCTGGCCATCCTGAGC
TGCAGCCTGAAGCTGCTCCGCCACGGCTGGATGGACGTGATCGGCGTGACCCTTCTGCTGGTGATGATAGCCGCAGGTCT
TCATACCGCTGCACCGCTGCTCATGGGCATCGGCAACTGGGCGCTGCTGGTGTTCTTCGTGGGGCTGCTGGGCGCGGGCG
TTCTGGCGGGCGTGCCCATCGCCTTCACCTTCGCCCTTGCCACCACCGCCTATCTGCTCACCGTCACCACCACGCCGCTG
ACCATTGTGGTCGGCCGCATGGACGAGGGCATGAGCGGCCTCATCCTGCTGGCCATCCCGCTCTTCGTCCTGCTGGGCCA
ACTGGTCGAGGTCACGGGCATGGCACGGGTCATGGTGGCTTTCCTCGCCTCGCTGCTGGGGCATGTGAAGGCGGGTATGT
CCTATGTGCTGCTGGGCGCCATGCTGCTGGTCTCCGGCATCTCCGGTTCCAAGACCGCCGACATGGCGGCCGTGGCCCCG
GTGCTGTTTCCCGAGATGCGCAAGCGCGGGATGAAGGACGGGGAACTGCTCTCGCTGCTCGCGGCCTCCGGCGCCATGAG
CGAGACCATTCCGCCCTCCATCGTGCTCATCGCCATCGCCTCCGTGACCGGCGTCTCCATCGCTGCGCTGTTCACGGCGG
GCATCCTGCCCGCCCTGGTGCTTGCGCTGGTTCTGGCCGTCGTCGCCCGCTACCGGGCGGGCAAGGAAGAGGACCAGAGC
GTGGTGCCCCGTGCGCCCCGCGCGGTGGTGATGAAGACCCTGCTGGTGGCGATCCCTGCGCTGCTGCTGCCCTTCCTCAT
CCGCACCGCGGTGGTCGAGGGCGTGGCAACCGCCACCGAGGTCTCCACCATCGGCATTGCCTATTCGCTGGTGCTGGGCC
TGCTGGTCTATCGCGGCGGCCTTAGCTGGCGCGGGGCCCTCCCGATGCTTGCGCGCACCGCCTCGCTCTCCGGCGCCATC
CTCTTCATCGTGGGGGCGGCAAGTGCCATGGCCTGGGCGCTCACCCAGTCCGGCTTCTCCCATGCTCTGGCTGCCGCCAT
GGCCGGCGTGCCCGGCGGACAGGTGGGCTTCCTGCTGATCTCGCTGGTGGCTTTCATCGTGCTCGGCAGCCTGCTGGAGG
GCATTCCCGCCATCGTGCTGTTCGGCCCGCTGCTGTTCCCGATCGCCCGCCAGTTCGGCATCCACGAGGTCCACTACAGC
ATGGTGGTGATCCTCGCGATGGGCCTCGGCCTCTTCGCTCCGCCGTTCGGCCTCTGCTACTACGCCGCCTGCATCATTGG
CGGGGTGAAGCCGGAAGCCGGGATGCGGCGCATCTGGATCTATCTGGGCGCCCTGTTCCTCGGTCTCCTGGCGCTCACCT
TCATCCCGTGGTTTTCCATCGGCTTCCTGTAG

Upstream 100 bases:

>100_bases
TCCGCAAGGAGCTGAGCGACAACGGCTTCTACAAGACCTGGAAGGACAAGTTCGGTACCGACGCCTGGAAGGCGCTCGAG
ACCGTGACGGGCGACCTGGC

Downstream 100 bases:

>100_bases
GATCCGCAGTCATGGGCCCCATTGCCGTGGGGTCCATGATCAGGAGGCCTTTCAGGTTCGGCGCAGGGGCACTGCGTGCA
GCGCCGAGGCCACCAGAAGA

Product: TRAP dicarboxylate transporter DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MSTVSHSQDTAWEAAAPAWVADAERWLRRIVEIPAALLVAAEVLILFVGICARSFHRPIIWSDELASILFLWLGMLGAVV
AIQRGEHMRLTFLVSMFSRRAQAWCETLAVGGVFVLLGLLMHAAYDYTLDQSFVEMPALGWSGMVRALAVPVGFTLAILS
CSLKLLRHGWMDVIGVTLLLVMIAAGLHTAAPLLMGIGNWALLVFFVGLLGAGVLAGVPIAFTFALATTAYLLTVTTTPL
TIVVGRMDEGMSGLILLAIPLFVLLGQLVEVTGMARVMVAFLASLLGHVKAGMSYVLLGAMLLVSGISGSKTADMAAVAP
VLFPEMRKRGMKDGELLSLLAASGAMSETIPPSIVLIAIASVTGVSIAALFTAGILPALVLALVLAVVARYRAGKEEDQS
VVPRAPRAVVMKTLLVAIPALLLPFLIRTAVVEGVATATEVSTIGIAYSLVLGLLVYRGGLSWRGALPMLARTASLSGAI
LFIVGAASAMAWALTQSGFSHALAAAMAGVPGGQVGFLLISLVAFIVLGSLLEGIPAIVLFGPLLFPIARQFGIHEVHYS
MVVILAMGLGLFAPPFGLCYYAACIIGGVKPEAGMRRIWIYLGALFLGLLALTFIPWFSIGFL

Sequences:

>Translated_623_residues
MSTVSHSQDTAWEAAAPAWVADAERWLRRIVEIPAALLVAAEVLILFVGICARSFHRPIIWSDELASILFLWLGMLGAVV
AIQRGEHMRLTFLVSMFSRRAQAWCETLAVGGVFVLLGLLMHAAYDYTLDQSFVEMPALGWSGMVRALAVPVGFTLAILS
CSLKLLRHGWMDVIGVTLLLVMIAAGLHTAAPLLMGIGNWALLVFFVGLLGAGVLAGVPIAFTFALATTAYLLTVTTTPL
TIVVGRMDEGMSGLILLAIPLFVLLGQLVEVTGMARVMVAFLASLLGHVKAGMSYVLLGAMLLVSGISGSKTADMAAVAP
VLFPEMRKRGMKDGELLSLLAASGAMSETIPPSIVLIAIASVTGVSIAALFTAGILPALVLALVLAVVARYRAGKEEDQS
VVPRAPRAVVMKTLLVAIPALLLPFLIRTAVVEGVATATEVSTIGIAYSLVLGLLVYRGGLSWRGALPMLARTASLSGAI
LFIVGAASAMAWALTQSGFSHALAAAMAGVPGGQVGFLLISLVAFIVLGSLLEGIPAIVLFGPLLFPIARQFGIHEVHYS
MVVILAMGLGLFAPPFGLCYYAACIIGGVKPEAGMRRIWIYLGALFLGLLALTFIPWFSIGFL
>Mature_622_residues
STVSHSQDTAWEAAAPAWVADAERWLRRIVEIPAALLVAAEVLILFVGICARSFHRPIIWSDELASILFLWLGMLGAVVA
IQRGEHMRLTFLVSMFSRRAQAWCETLAVGGVFVLLGLLMHAAYDYTLDQSFVEMPALGWSGMVRALAVPVGFTLAILSC
SLKLLRHGWMDVIGVTLLLVMIAAGLHTAAPLLMGIGNWALLVFFVGLLGAGVLAGVPIAFTFALATTAYLLTVTTTPLT
IVVGRMDEGMSGLILLAIPLFVLLGQLVEVTGMARVMVAFLASLLGHVKAGMSYVLLGAMLLVSGISGSKTADMAAVAPV
LFPEMRKRGMKDGELLSLLAASGAMSETIPPSIVLIAIASVTGVSIAALFTAGILPALVLALVLAVVARYRAGKEEDQSV
VPRAPRAVVMKTLLVAIPALLLPFLIRTAVVEGVATATEVSTIGIAYSLVLGLLVYRGGLSWRGALPMLARTASLSGAIL
FIVGAASAMAWALTQSGFSHALAAAMAGVPGGQVGFLLISLVAFIVLGSLLEGIPAIVLFGPLLFPIARQFGIHEVHYSM
VVILAMGLGLFAPPFGLCYYAACIIGGVKPEAGMRRIWIYLGALFLGLLALTFIPWFSIGFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=414, Percent_Identity=26.8115942028986, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65572; Mature: 65441

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVSHSQDTAWEAAAPAWVADAERWLRRIVEIPAALLVAAEVLILFVGICARSFHRPII
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WSDELASILFLWLGMLGAVVAIQRGEHMRLTFLVSMFSRRAQAWCETLAVGGVFVLLGLL
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHAAYDYTLDQSFVEMPALGWSGMVRALAVPVGFTLAILSCSLKLLRHGWMDVIGVTLLL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMIAAGLHTAAPLLMGIGNWALLVFFVGLLGAGVLAGVPIAFTFALATTAYLLTVTTTPL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCC
TIVVGRMDEGMSGLILLAIPLFVLLGQLVEVTGMARVMVAFLASLLGHVKAGMSYVLLGA
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLVSGISGSKTADMAAVAPVLFPEMRKRGMKDGELLSLLAASGAMSETIPPSIVLIAIA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
SVTGVSIAALFTAGILPALVLALVLAVVARYRAGKEEDQSVVPRAPRAVVMKTLLVAIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLLPFLIRTAVVEGVATATEVSTIGIAYSLVLGLLVYRGGLSWRGALPMLARTASLSGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHH
LFIVGAASAMAWALTQSGFSHALAAAMAGVPGGQVGFLLISLVAFIVLGSLLEGIPAIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGPLLFPIARQFGIHEVHYSMVVILAMGLGLFAPPFGLCYYAACIIGGVKPEAGMRRIWI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
YLGALFLGLLALTFIPWFSIGFL
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STVSHSQDTAWEAAAPAWVADAERWLRRIVEIPAALLVAAEVLILFVGICARSFHRPII
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC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HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]