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The map label for this gene is yusP [H]

Identifier: 158423484

GI number: 158423484

Start: 2127120

End: 2128778

Strand: Direct

Name: yusP [H]

Synonym: AZC_1860

Alternate gene names: 158423484

Gene position: 2127120-2128778 (Clockwise)

Preceding gene: 158423478

Following gene: 158423487

Centisome position: 39.61

GC content: 67.09

Gene sequence:

>1659_bases
GTGGCAGGATTGTGGTGGCGGCGCGCACCTGCCGCATACGTTGCGTCGGCGCCATGCGGCACCGGCCTTGTCCGGTTGGT
GGTTGTGAAGAACAATAATCAGTACAACTTAGCATCTGAGGGCACCCCGGACACCGCCGCGCCGCCGGGCGTGCCAGAGG
CCCCCATGTCCGTCACTGCCGCCGCTCCTGCCCAGCTCGACCATTCCGAAATCCGCTCCATCCTCTTCGGCGTCATGCTG
GCCATGCTGCTGGCGGCGCTGGACCAGACCATCGTGGCCACGGCCCTGCCCACGATCGGCGCCGATCTCGGGGATTTCGA
GAGCCTGTCCTGGGTGGTGACGGCCTATCTGCTGACCTCGACCGCCGTGACGCCGCTCTATGGCCGGCTCAGCGACGTGC
ATGGGCGGCGCATGATGATGCTCATCGCCATCTCGATCTTCTCGGTCGGCTCGCTCGCCTGCGCGCTCGCCCCCAACATG
GTGGTGCTGATCTTCGCCCGCGGTCTTCAGGGGCTCGGCGGCGGCGGACTGATCTCGCTGGCCCAGACCATCATTGCGGA
CATCGTGTCTCCCCGCGAGCGCGGACGCTATCAGGGCTATTTCGCAAGTGTCTTCATGGCGAGCAGCCTGTGCGGGCCGG
TGCTCGGCGGCGTGCTGGCGCAGCATCTGCACTGGTCGCTCATCTTCTGGATCAACCTGCCGCTCGGCCTCGCGGCCTAT
TTCATGACCGACCGCCAGCTCCGCCGCCTGCCGCGCCACGAGCGCAAGGCCAAGGTGGATGTCATCGGCGCCGTGCTGAT
GGTCGTCTCCACCATTTCCCTGCTGCTGCTTCTGACCTGGGGCGGTGTGCGCTACGCTTGGGATGCGCCGGAAATCCTCG
CGCTCGGCGGTGCCGCGGTGATCTTCGCCGTGCTCTTCGTCTGGCGCTTGCGCACCGCCGACGAACCTTTCCTGCCGCTG
CCGGTCCTCCTGCATCCGGTGGTGGCGCGCGGCACGGCCACCGCTCTGATGACCATGGGCACGCTGATCGCCCTGTCCAT
CAATGTGCCGCTCTATTTCGAGACCGCGCGCGGCCTGTCTGCCAGCCAATCGGGCCTCGCCCTCATTCCGCTCATGGGCG
GCGTGGTGCTGGGGGCTCTCCTCGCCGGCCGGGCGCTGTTCATGCTCGAGCACTACAAGCGCGTGGCCATCTCCGGTATC
GCAGTGGCCATTCTCGGTCTGCTGTTTCTGTCGCTGGGCCCGGAACGGCCGCCGCTGCCGCTGATGCTGCTCGTGTTCGG
CCTGATGGGCATCGGCATCGGCTGCGTGCTGCCCATCACCACGGTTTCGATCCAGAACGCCGTGGAGCCGCATCAGATGG
GCACCGCCACCGGCACCATGAACTTCTTCCGCTCGCTCGGCTCGGCGGTTCTGGTGGCGGGCTTCGGCGCGGTGCTGATG
GCCGCCCTTGGTCTGGGGCCGGGGCAGGGCAATCTCGAACAGCTCATCGGCGGCGCCGATCAGGCGGGGCTCGCCTCCGC
CTTCCGTATCGTCTTCGGCTGCGCTTCCGTCACGCTGATGCTGGGGCTTCTTGCGCTGATGAGCATGGAGCAGAAGCCGT
TGCGCACGAGCGTCCGAAAGACCTCCGAAGAAGGCGGGGTGGTCGGCGTCGGCGAATAG

Upstream 100 bases:

>100_bases
CGTGAGGCGCGCGAGGCCCCGGCACGGGCCGCAGGCTAGTGCAGCGGGCCCCTGATTTCAAAGTCATTCCACGATTTGTG
GAAGGCAGCCGCCGCGGCTT

Downstream 100 bases:

>100_bases
CGCCGACGCCCTGTCCCGTCACTCCTCGGCCGCGGCGTCCGCCTTGGCCTTGGCGGTCTTCTTCGTCCCCGCAGCCTTGG
TGGTGGTCTTCTTGGCGGCG

Product: membrane transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MAGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTAAAPAQLDHSEIRSILFGVML
AMLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTSTAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNM
VVLIFARGLQGLGGGGLISLAQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAY
FMTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAVIFAVLFVWRLRTADEPFLPL
PVLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLSASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGI
AVAILGLLFLSLGPERPPLPLMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLM
AALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRKTSEEGGVVGVGE

Sequences:

>Translated_552_residues
MAGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTAAAPAQLDHSEIRSILFGVML
AMLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTSTAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNM
VVLIFARGLQGLGGGGLISLAQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAY
FMTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAVIFAVLFVWRLRTADEPFLPL
PVLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLSASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGI
AVAILGLLFLSLGPERPPLPLMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLM
AALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRKTSEEGGVVGVGE
>Mature_551_residues
AGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTAAAPAQLDHSEIRSILFGVMLA
MLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTSTAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNMV
VLIFARGLQGLGGGGLISLAQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAYF
MTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAVIFAVLFVWRLRTADEPFLPLP
VLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLSASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGIA
VAILGLLFLSLGPERPPLPLMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLMA
ALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRKTSEEGGVVGVGE

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=26.5060240963855, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788710, Length=423, Percent_Identity=26.9503546099291, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=27.3607748184019, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1790195, Length=362, Percent_Identity=25.414364640884, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788392, Length=357, Percent_Identity=28.2913165266106, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790146, Length=207, Percent_Identity=25.1207729468599, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=435, Percent_Identity=28.2758620689655, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319770, Length=381, Percent_Identity=28.0839895013123, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6322958, Length=441, Percent_Identity=26.530612244898, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6325455, Length=264, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321663, Length=351, Percent_Identity=24.7863247863248, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324264, Length=209, Percent_Identity=24.4019138755981, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57883; Mature: 57751

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTA
CCCCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEEE
AAPAQLDHSEIRSILFGVMLAMLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNMVVLIFARGLQGLGGGGLISL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
AQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAY
HHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHH
FMTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAV
HHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCHHH
IFAVLFVWRLRTADEPFLPLPVLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCC
ASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGIAVAILGLLFLSLGPERPPLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRK
HHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TSEEGGVVGVGE
HCCCCCEEECCC
>Mature Secondary Structure 
AGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTA
CCCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEEE
AAPAQLDHSEIRSILFGVMLAMLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNMVVLIFARGLQGLGGGGLISL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
AQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAY
HHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHH
FMTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAV
HHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCHHH
IFAVLFVWRLRTADEPFLPLPVLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCC
ASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGIAVAILGLLFLSLGPERPPLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRK
HHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TSEEGGVVGVGE
HCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]