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The map label for this gene is cutL [H]

Identifier: 158423444

GI number: 158423444

Start: 2081369

End: 2083681

Strand: Direct

Name: cutL [H]

Synonym: AZC_1820

Alternate gene names: 158423444

Gene position: 2081369-2083681 (Clockwise)

Preceding gene: 158423443

Following gene: 158423445

Centisome position: 38.76

GC content: 69.52

Gene sequence:

>2313_bases
GTGGAGGTGCGGATGAAGTTCGGCGTCGGTCAGCCCCACACGCGCGTCGAGGACGCGGCCCTGCTCTCCGGTGCCGGCCG
CTATGTGGGCGATGCTGCCGCCCGTGCGCAGGCCTACGCCGCTTTCGTGGTCCGCTCCCCCCACGCCCATGCGCGTTTCT
CCTTCCCCGATCTCGGGGCGGCGCGCGTGCTGCCGGGGGTGAAGCTCGTCCTGACCGCCGAGGACATTGCCGAGTTCGGC
TCCATGCCCGTGGCGGCCACCATCACCGTCACCGGTGAGGACCGGCTCTGGATCCCGCCCCATCCGGCGCTGGCGGACGG
CATTGCCCGCCACGTGGGCGATCCGGTCGCTGTCATCGTGGCCGAGACGCTGGACATGGCGCGGGATGCGGCCGAGGCGA
TGGAGATCGACTGGGAGTCGCTTCCCGCCGTCGCCGAGCTTGCCGCAGCCGCCGAGGACGAGGCACCGCTTGTCTGGACG
GAGCGGCCCGGCAACATCGCCTTCACTTCGGAATTCGGAGACGCGGCGGCCGCCGACACCGCCTTCGCCGGCGCGGCGCA
TGTGGCGCGGCTGCGGCTCGTCAACAATCGCATCGTCACCAATTACATGGAGACGCGGGGCGTCTTGGCGGAGGTGGAGG
AGACGGGACGCATCCGTCTCACCCTCGGCAGCCAGGGCAGCCACCTGCTGCGCAATGCCATCGCCGACAAGGTGCTGAAG
TGGGACCGCGAGGACCTGCGCGTGGTCACGCCGGACGTTGGCGGTGGCTTCGGCACCAAGATGTTCCCCTTCAGCGAATA
TCCGCTCATCGCCTTTGCCGCCCGCGTTCTGGGCCATGCGGTGGCGTGGATCGGCGACCGCAGCGAGCATTTCCTCGCCG
ACAGCCAGGGCCGCGACAACATCACCGACGTGGCGCTGGCGCTCGACGCCGATGGCCACTTCATCGGCCTTGAGGTCGAT
ACGATTGCCAATATGGGCGCCTACCTCTCCTATTACGGCCCGTTCGTGCCGTGGGGCGGCGCCTCCATGCTGCCCGGCGT
CTATCGCATCGGCGCCTTCCATGCGCGGGTGCGCGGCGTCTATTCCCATTCGGCCCCGGTGGATGCCTATCGCGGGGCGG
GCCGTCCCGAGGCGGCCTATGTGATCGAGCGCATCGTGGATGCGGCCGCGCGCGAGACGGGCATCCCGCCCGAGGAACTG
CGCCGGCGCAACTTCATCCACCCCGAGGAGATGCCGTTCCGCACGAAGACGGGGCGGCTCTATGACAGCGGCGAGTTCGA
TGGCCACATGACCCGTGCGCTGGAAGTGGCCGACCATGCCGGCTTTTCGGAACGGGCGGAACGCTCGGCGGCGGCCGGCA
AGATGCGCGGCTTCGGCTTTGCCTGCTACATTGAGGCCTGCGGCGGGGGCACGGCCGAGCCGGCCTTCCTCACGCTCGGC
ACGGATGGCGGCGTTACCGTGAAGATCGGCAGCCAGTCGAGCGGGCAGGGCCATCAGACGGCCTATGCCCAGCTCGTCGC
CTCCGAGCTGCAACTGCCGCTCGAACAGGTACGGGTGCTCCAGGGCGACACCGACGATCTGCCGGCCGGTTCCGGCACAG
GCGGCTCGCGCTCCATCCCCATCGGCGGCGCGGCCGTGAAGGGCGCGGCGCGGCACATGGCCGAGAAGCTCAAATCCCTC
GGGGCCGAGGCGCTGGAGGCGGATGCGGCGGACCTCGAATTCCTTGATGGCGCCCTCGTGGTGGCAGGCACCGACCGGCG
CCTGACGCTGGCCGAACTCGCCAACCATCCGGCGGCGACCGCCGAACATCTGTCGGCGACCGACGCCTTCTCGGCCTCCG
AGGCCACCTATCCCAACGGCACCCATGCCTGCGAGGTGGAGATCGATCCCGACACCGGCTCCGTCGAGATCCTGCGCTAT
GTGGTGGTGGACGATTTCGGCGTGACGCTGAACCCGCTGCTGCTGGCCGGACAGGTGCACGGCGGCATCGTGCAGGGGGT
GGGGCAGGCGTTGCACGAACGCACCGTCTATGACGAGGACGGCCAGCTCCTCACCGCCAGCTTCATGGACTATGCCTTGC
CGCGCGCAGCGGACCTGCCGGACATCCATTTCGAGACCCGCAACGTGCCCTGCCGCACCAATCCGCTGGGTGTGAAGGGC
GCGGGCGAGGCGGGCGCCATCGGCTCGTGCCCGGCAGTCATGAACGCAGTGGTGGACGCGCTGGCGCGGGGCTGCGGCGT
GACGCACATCGACATGCCGGCGACGCCGCTTGCGGTGTTCGACGCCATTACGAGCGTACAGCCGGCAACCTGA

Upstream 100 bases:

>100_bases
GGAGGTTCATGGGCTTCCGGCCCGCCATGCGGCGGCGCATCATCGCGCCTGCGCATGGGCGTGCTACCGATGAGCATGCT
ACCCATGGGCGGCAGAAACG

Downstream 100 bases:

>100_bases
CGCAACGTTCCCGGTTTCCTGGAAGAAACGTACCGGCGGACGGGAAAGGCAAAATAACCTGCAACTCTTCCGGGATGATC
TGTGTCTTTACCATCACGCT

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MEVRMKFGVGQPHTRVEDAALLSGAGRYVGDAAARAQAYAAFVVRSPHAHARFSFPDLGAARVLPGVKLVLTAEDIAEFG
SMPVAATITVTGEDRLWIPPHPALADGIARHVGDPVAVIVAETLDMARDAAEAMEIDWESLPAVAELAAAAEDEAPLVWT
ERPGNIAFTSEFGDAAAADTAFAGAAHVARLRLVNNRIVTNYMETRGVLAEVEETGRIRLTLGSQGSHLLRNAIADKVLK
WDREDLRVVTPDVGGGFGTKMFPFSEYPLIAFAARVLGHAVAWIGDRSEHFLADSQGRDNITDVALALDADGHFIGLEVD
TIANMGAYLSYYGPFVPWGGASMLPGVYRIGAFHARVRGVYSHSAPVDAYRGAGRPEAAYVIERIVDAAARETGIPPEEL
RRRNFIHPEEMPFRTKTGRLYDSGEFDGHMTRALEVADHAGFSERAERSAAAGKMRGFGFACYIEACGGGTAEPAFLTLG
TDGGVTVKIGSQSSGQGHQTAYAQLVASELQLPLEQVRVLQGDTDDLPAGSGTGGSRSIPIGGAAVKGAARHMAEKLKSL
GAEALEADAADLEFLDGALVVAGTDRRLTLAELANHPAATAEHLSATDAFSASEATYPNGTHACEVEIDPDTGSVEILRY
VVVDDFGVTLNPLLLAGQVHGGIVQGVGQALHERTVYDEDGQLLTASFMDYALPRAADLPDIHFETRNVPCRTNPLGVKG
AGEAGAIGSCPAVMNAVVDALARGCGVTHIDMPATPLAVFDAITSVQPAT

Sequences:

>Translated_770_residues
MEVRMKFGVGQPHTRVEDAALLSGAGRYVGDAAARAQAYAAFVVRSPHAHARFSFPDLGAARVLPGVKLVLTAEDIAEFG
SMPVAATITVTGEDRLWIPPHPALADGIARHVGDPVAVIVAETLDMARDAAEAMEIDWESLPAVAELAAAAEDEAPLVWT
ERPGNIAFTSEFGDAAAADTAFAGAAHVARLRLVNNRIVTNYMETRGVLAEVEETGRIRLTLGSQGSHLLRNAIADKVLK
WDREDLRVVTPDVGGGFGTKMFPFSEYPLIAFAARVLGHAVAWIGDRSEHFLADSQGRDNITDVALALDADGHFIGLEVD
TIANMGAYLSYYGPFVPWGGASMLPGVYRIGAFHARVRGVYSHSAPVDAYRGAGRPEAAYVIERIVDAAARETGIPPEEL
RRRNFIHPEEMPFRTKTGRLYDSGEFDGHMTRALEVADHAGFSERAERSAAAGKMRGFGFACYIEACGGGTAEPAFLTLG
TDGGVTVKIGSQSSGQGHQTAYAQLVASELQLPLEQVRVLQGDTDDLPAGSGTGGSRSIPIGGAAVKGAARHMAEKLKSL
GAEALEADAADLEFLDGALVVAGTDRRLTLAELANHPAATAEHLSATDAFSASEATYPNGTHACEVEIDPDTGSVEILRY
VVVDDFGVTLNPLLLAGQVHGGIVQGVGQALHERTVYDEDGQLLTASFMDYALPRAADLPDIHFETRNVPCRTNPLGVKG
AGEAGAIGSCPAVMNAVVDALARGCGVTHIDMPATPLAVFDAITSVQPAT
>Mature_770_residues
MEVRMKFGVGQPHTRVEDAALLSGAGRYVGDAAARAQAYAAFVVRSPHAHARFSFPDLGAARVLPGVKLVLTAEDIAEFG
SMPVAATITVTGEDRLWIPPHPALADGIARHVGDPVAVIVAETLDMARDAAEAMEIDWESLPAVAELAAAAEDEAPLVWT
ERPGNIAFTSEFGDAAAADTAFAGAAHVARLRLVNNRIVTNYMETRGVLAEVEETGRIRLTLGSQGSHLLRNAIADKVLK
WDREDLRVVTPDVGGGFGTKMFPFSEYPLIAFAARVLGHAVAWIGDRSEHFLADSQGRDNITDVALALDADGHFIGLEVD
TIANMGAYLSYYGPFVPWGGASMLPGVYRIGAFHARVRGVYSHSAPVDAYRGAGRPEAAYVIERIVDAAARETGIPPEEL
RRRNFIHPEEMPFRTKTGRLYDSGEFDGHMTRALEVADHAGFSERAERSAAAGKMRGFGFACYIEACGGGTAEPAFLTLG
TDGGVTVKIGSQSSGQGHQTAYAQLVASELQLPLEQVRVLQGDTDDLPAGSGTGGSRSIPIGGAAVKGAARHMAEKLKSL
GAEALEADAADLEFLDGALVVAGTDRRLTLAELANHPAATAEHLSATDAFSASEATYPNGTHACEVEIDPDTGSVEILRY
VVVDDFGVTLNPLLLAGQVHGGIVQGVGQALHERTVYDEDGQLLTASFMDYALPRAADLPDIHFETRNVPCRTNPLGVKG
AGEAGAIGSCPAVMNAVVDALARGCGVTHIDMPATPLAVFDAITSVQPAT

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=798, Percent_Identity=23.9348370927318, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI71773480, Length=795, Percent_Identity=23.1446540880503, Blast_Score=139, Evalue=7e-33,
Organism=Escherichia coli, GI1789230, Length=768, Percent_Identity=29.8177083333333, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1789246, Length=808, Percent_Identity=25, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786478, Length=784, Percent_Identity=26.6581632653061, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=756, Percent_Identity=23.9417989417989, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=773, Percent_Identity=23.8033635187581, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32566215, Length=562, Percent_Identity=24.3772241992883, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17737937, Length=711, Percent_Identity=23.9099859353024, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24647199, Length=754, Percent_Identity=23.342175066313, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647201, Length=776, Percent_Identity=24.4845360824742, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647197, Length=257, Percent_Identity=30.3501945525292, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647195, Length=257, Percent_Identity=30.3501945525292, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81180; Mature: 81180

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRMKFGVGQPHTRVEDAALLSGAGRYVGDAAARAQAYAAFVVRSPHAHARFSFPDLGA
CEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCEECCCCCCH
ARVLPGVKLVLTAEDIAEFGSMPVAATITVTGEDRLWIPPHPALADGIARHVGDPVAVIV
HHHCCCCEEEEEHHHHHHHCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHCCCCEEEHH
AETLDMARDAAEAMEIDWESLPAVAELAAAAEDEAPLVWTERPGNIAFTSEFGDAAAADT
HHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCHHHHH
AFAGAAHVARLRLVNNRIVTNYMETRGVLAEVEETGRIRLTLGSQGSHLLRNAIADKVLK
HHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
WDREDLRVVTPDVGGGFGTKMFPFSEYPLIAFAARVLGHAVAWIGDRSEHFLADSQGRDN
CCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
ITDVALALDADGHFIGLEVDTIANMGAYLSYYGPFVPWGGASMLPGVYRIGAFHARVRGV
CEEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YSHSAPVDAYRGAGRPEAAYVIERIVDAAARETGIPPEELRRRNFIHPEEMPFRTKTGRL
HCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCE
YDSGEFDGHMTRALEVADHAGFSERAERSAAAGKMRGFGFACYIEACGGGTAEPAFLTLG
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEE
TDGGVTVKIGSQSSGQGHQTAYAQLVASELQLPLEQVRVLQGDTDDLPAGSGTGGSRSIP
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
IGGAAVKGAARHMAEKLKSLGAEALEADAADLEFLDGALVVAGTDRRLTLAELANHPAAT
CCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCEEEEECCCCCEEHHHHHCCCCHH
AEHLSATDAFSASEATYPNGTHACEVEIDPDTGSVEILRYVVVDDFGVTLNPLLLAGQVH
HHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEECCCC
GGIVQGVGQALHERTVYDEDGQLLTASFMDYALPRAADLPDIHFETRNVPCRTNPLGVKG
CHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
AGEAGAIGSCPAVMNAVVDALARGCGVTHIDMPATPLAVFDAITSVQPAT
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEVRMKFGVGQPHTRVEDAALLSGAGRYVGDAAARAQAYAAFVVRSPHAHARFSFPDLGA
CEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCEECCCCCCH
ARVLPGVKLVLTAEDIAEFGSMPVAATITVTGEDRLWIPPHPALADGIARHVGDPVAVIV
HHHCCCCEEEEEHHHHHHHCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHCCCCEEEHH
AETLDMARDAAEAMEIDWESLPAVAELAAAAEDEAPLVWTERPGNIAFTSEFGDAAAADT
HHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCCCHHHHH
AFAGAAHVARLRLVNNRIVTNYMETRGVLAEVEETGRIRLTLGSQGSHLLRNAIADKVLK
HHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
WDREDLRVVTPDVGGGFGTKMFPFSEYPLIAFAARVLGHAVAWIGDRSEHFLADSQGRDN
CCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
ITDVALALDADGHFIGLEVDTIANMGAYLSYYGPFVPWGGASMLPGVYRIGAFHARVRGV
CEEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YSHSAPVDAYRGAGRPEAAYVIERIVDAAARETGIPPEELRRRNFIHPEEMPFRTKTGRL
HCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCE
YDSGEFDGHMTRALEVADHAGFSERAERSAAAGKMRGFGFACYIEACGGGTAEPAFLTLG
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEE
TDGGVTVKIGSQSSGQGHQTAYAQLVASELQLPLEQVRVLQGDTDDLPAGSGTGGSRSIP
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
IGGAAVKGAARHMAEKLKSLGAEALEADAADLEFLDGALVVAGTDRRLTLAELANHPAAT
CCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCEEEEECCCCCEEHHHHHCCCCHH
AEHLSATDAFSASEATYPNGTHACEVEIDPDTGSVEILRYVVVDDFGVTLNPLLLAGQVH
HHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEECCCC
GGIVQGVGQALHERTVYDEDGQLLTASFMDYALPRAADLPDIHFETRNVPCRTNPLGVKG
CHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
AGEAGAIGSCPAVMNAVVDALARGCGVTHIDMPATPLAVFDAITSVQPAT
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]