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The map label for this gene is ytfL [C]

Identifier: 158423374

GI number: 158423374

Start: 2001058

End: 2002395

Strand: Direct

Name: ytfL [C]

Synonym: AZC_1750

Alternate gene names: 158423374

Gene position: 2001058-2002395 (Clockwise)

Preceding gene: 158423372

Following gene: 158423379

Centisome position: 37.27

GC content: 67.34

Gene sequence:

>1338_bases
ATGCCCATTCTCGAAATCGCGATTGTTCTTTTTCTTGTTCTCTTGAACGCCCTTCTCGCCGCGGCTGAGCTGTCCATCGT
CTCGGTGCGTCCGGCGCGGCTCAAGGCCCGTGCGGATGCCGGCCACCGGGGCGCCAAGGCTGCCCTGCTGCTCGGCGCCG
AACCGGGGCGCTTCCTCTCCGTGGTGCAGATCGGCATCACCCTCATCGGCATCCTCGCCGGCGCCTTTTCCGGCGCCAGC
CTCGGCGCCTATCTGGCGGAGGTCTTCGTGGGGGCCGGTCTGCCCCATTCGGCCGCCGATCCCCTGGGGTATGCCGTGGC
GGTGGGCGGCATCACCTATGTCTCGCTCATCATCGGCGAGCTGATTCCCAAGCGCCTCGCCCTTCAGAACCCCGAGCGCC
TCGCCTGCGTGCTGGCGCCGTTGATGCTTAGTCTTTCCAAGTTCGCGGCGCCGGCGGTGTGGGTGCTCGATGCCTCTGCC
CGTGGCGTGCTGCGCCTGCTGGGCGAGAAGGACAGCAAGAAGGAAGCGGTCACCGACGAGGAAATCCGCGCCATCATCAC
CGAGGCGGAGACCGCCGGCGTGATCGACCCGGCCGAGCGGCGGATGATCTCCGGCGTCATGCGCCTCGCCGACCGCCCGG
TCACCGCCATCATGACCCCCCGTCCGGATGTCGAATGGGTGGATGTGACGGCCGATCCTGAGGAGATTCGCCAAATCCTG
CTGGAGACGCCGCACAGCCGCGTGCCTGCCTGCGAGGGCTCGCCCGAGGAGACCGTGGGCGTCATTCAGGCCAAGAAGCT
GCTGAACGCCTATCTCCGCGGCGAGACGCCGGATCCGCGGACCTTCGTGGAGGCGGTGCCCTTCGTGGTGGAAACCATCG
GCGCGCTGGAGGCCATGCGCGTGCTGCGCGGGGCCAGCGTGCCCATGGGCATCGTCGTGGACGAGTATGGCGATATGGTC
GGCGTCGTCACCGGCTACGACCTGCTCGCCGCCATCACCGGCACCATTCTGGAGCAGGGGGATGAGGCCACCATCGTGCT
CGATGGCGACGAACCCCATGTGGTCCAGCGCCTCGACGGCTCCTATCTGATCTCCGGCGAGATGCCCATCGACGACCTGC
ACGACGTGCTGGGCGTGGAAATTCAGGTGGATGGCCGCTTCAATACGGTGGCGGGCTTTGCGCTGGCGCACCTGAAGGAG
ATGCCCAAGGTGGGCACGGTGTTCGACGCGCTGGGCTGGCGCTTCGAGATCGTGGACATGGACGGGCGGCGCATCGACAA
GCTGCTGATCTCCCGCCCGCCGGTCCTGCACCGGCAGAAGACGCTCCGGACGGCCTGA

Upstream 100 bases:

>100_bases
CAAGCACTGTCGCACCTCAAACGGGCTTTTGACCGGCTGTCACGCACAGACGGGGCGAGCTGTGTTATGGAGGAGGTGAC
GGAAGGTCCAACACTCTCCC

Downstream 100 bases:

>100_bases
GGGCCGTCCCGGGGACCAACGCCTAGTCCTTCACCTCGAAGGCGCCGTCGCTCAGCACATAGATGGCGCCCTGGCGGATC
GGCACCACGGCAGCCTCGTT

Product: HlyC/CorC family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MPILEIAIVLFLVLLNALLAAAELSIVSVRPARLKARADAGHRGAKAALLLGAEPGRFLSVVQIGITLIGILAGAFSGAS
LGAYLAEVFVGAGLPHSAADPLGYAVAVGGITYVSLIIGELIPKRLALQNPERLACVLAPLMLSLSKFAAPAVWVLDASA
RGVLRLLGEKDSKKEAVTDEEIRAIITEAETAGVIDPAERRMISGVMRLADRPVTAIMTPRPDVEWVDVTADPEEIRQIL
LETPHSRVPACEGSPEETVGVIQAKKLLNAYLRGETPDPRTFVEAVPFVVETIGALEAMRVLRGASVPMGIVVDEYGDMV
GVVTGYDLLAAITGTILEQGDEATIVLDGDEPHVVQRLDGSYLISGEMPIDDLHDVLGVEIQVDGRFNTVAGFALAHLKE
MPKVGTVFDALGWRFEIVDMDGRRIDKLLISRPPVLHRQKTLRTA

Sequences:

>Translated_445_residues
MPILEIAIVLFLVLLNALLAAAELSIVSVRPARLKARADAGHRGAKAALLLGAEPGRFLSVVQIGITLIGILAGAFSGAS
LGAYLAEVFVGAGLPHSAADPLGYAVAVGGITYVSLIIGELIPKRLALQNPERLACVLAPLMLSLSKFAAPAVWVLDASA
RGVLRLLGEKDSKKEAVTDEEIRAIITEAETAGVIDPAERRMISGVMRLADRPVTAIMTPRPDVEWVDVTADPEEIRQIL
LETPHSRVPACEGSPEETVGVIQAKKLLNAYLRGETPDPRTFVEAVPFVVETIGALEAMRVLRGASVPMGIVVDEYGDMV
GVVTGYDLLAAITGTILEQGDEATIVLDGDEPHVVQRLDGSYLISGEMPIDDLHDVLGVEIQVDGRFNTVAGFALAHLKE
MPKVGTVFDALGWRFEIVDMDGRRIDKLLISRPPVLHRQKTLRTA
>Mature_444_residues
PILEIAIVLFLVLLNALLAAAELSIVSVRPARLKARADAGHRGAKAALLLGAEPGRFLSVVQIGITLIGILAGAFSGASL
GAYLAEVFVGAGLPHSAADPLGYAVAVGGITYVSLIIGELIPKRLALQNPERLACVLAPLMLSLSKFAAPAVWVLDASAR
GVLRLLGEKDSKKEAVTDEEIRAIITEAETAGVIDPAERRMISGVMRLADRPVTAIMTPRPDVEWVDVTADPEEIRQILL
ETPHSRVPACEGSPEETVGVIQAKKLLNAYLRGETPDPRTFVEAVPFVVETIGALEAMRVLRGASVPMGIVVDEYGDMVG
VVTGYDLLAAITGTILEQGDEATIVLDGDEPHVVQRLDGSYLISGEMPIDDLHDVLGVEIQVDGRFNTVAGFALAHLKEM
PKVGTVFDALGWRFEIVDMDGRRIDKLLISRPPVLHRQKTLRTA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=26.1658031088083, Blast_Score=175, Evalue=6e-44,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=28.538283062645, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=30.6569343065693, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=27.0334928229665, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788119, Length=282, Percent_Identity=31.2056737588652, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1786879, Length=279, Percent_Identity=25.4480286738351, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47532; Mature: 47401

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILEIAIVLFLVLLNALLAAAELSIVSVRPARLKARADAGHRGAKAALLLGAEPGRFLS
CCHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCCCCCEEEEEECCCCHHHH
VVQIGITLIGILAGAFSGASLGAYLAEVFVGAGLPHSAADPLGYAVAVGGITYVSLIIGE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIPKRLALQNPERLACVLAPLMLSLSKFAAPAVWVLDASARGVLRLLGEKDSKKEAVTDE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCHHCCCHH
EIRAIITEAETAGVIDPAERRMISGVMRLADRPVTAIMTPRPDVEWVDVTADPEEIRQIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHHHH
LETPHSRVPACEGSPEETVGVIQAKKLLNAYLRGETPDPRTFVEAVPFVVETIGALEAMR
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLRGASVPMGIVVDEYGDMVGVVTGYDLLAAITGTILEQGDEATIVLDGDEPHVVQRLDG
HHHCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCC
SYLISGEMPIDDLHDVLGVEIQVDGRFNTVAGFALAHLKEMPKVGTVFDALGWRFEIVDM
CEEEECCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEC
DGRRIDKLLISRPPVLHRQKTLRTA
CCHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PILEIAIVLFLVLLNALLAAAELSIVSVRPARLKARADAGHRGAKAALLLGAEPGRFLS
CHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCCCCCCCEEEEEECCCCHHHH
VVQIGITLIGILAGAFSGASLGAYLAEVFVGAGLPHSAADPLGYAVAVGGITYVSLIIGE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIPKRLALQNPERLACVLAPLMLSLSKFAAPAVWVLDASARGVLRLLGEKDSKKEAVTDE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCHHCCCHH
EIRAIITEAETAGVIDPAERRMISGVMRLADRPVTAIMTPRPDVEWVDVTADPEEIRQIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHHHH
LETPHSRVPACEGSPEETVGVIQAKKLLNAYLRGETPDPRTFVEAVPFVVETIGALEAMR
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLRGASVPMGIVVDEYGDMVGVVTGYDLLAAITGTILEQGDEATIVLDGDEPHVVQRLDG
HHHCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCC
SYLISGEMPIDDLHDVLGVEIQVDGRFNTVAGFALAHLKEMPKVGTVFDALGWRFEIVDM
CEEEECCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEC
DGRRIDKLLISRPPVLHRQKTLRTA
CCHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]