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The map label for this gene is echA6 [H]

Identifier: 158423155

GI number: 158423155

Start: 1744695

End: 1745498

Strand: Reverse

Name: echA6 [H]

Synonym: AZC_1531

Alternate gene names: 158423155

Gene position: 1745498-1744695 (Counterclockwise)

Preceding gene: 158423156

Following gene: 158423150

Centisome position: 32.51

GC content: 73.26

Gene sequence:

>804_bases
ATGACGTCCGCACCCGCGCCGGCCTCAAGCGCCGTTTTCGTCACCGTGGAGGGCGGCATCGCCCGTCTCGTCCTGTCCAA
TCCCCAGCGCCGCAATGCCATCTCGAGCGGCATGTGGAAGACGCTGGCGGACTTCGCCGCCGAGGCGGGAGGCCGCAGCG
ACATCCGCGCGGCGGTGATCCGGGGTGAGGGCACGCTGGCCTTCTCGGGCGGGGCAGACATTTCCGATTTCGACGCCGCG
CGGGCGGACGCCTCCGGCGCGCAGACCTATGACGACGTGGTGGAAGCGGCCTGTGCCGCCTTCCAGGCCCTGCCCTTTCC
CACCCTCGCCCTCGTGCACGGGGCCTGCGTCGGTGCCGGTGCGGCGCTTTCCGCCTGCTGCGACCTGCGCCTTGCGGCGA
CGGACGCCTTCTTCGCCATTCCTGCCGCGCGCCTCGGCCTCGGCTATGATCCGCGCGGCGTCTCCCGCCTCGTGCGTGCC
TTCGGCCCGCAAGCCGCTCGGCTGATGCTGTTCACCGCCGAGCGCCTGCCGGCGGAGCGCGCCTTCGCCCTTGGTGCCGT
GGACGAGATCGCCGCCGCGGACGCGGTGGACGCGGCCGCAGAGCGCCTGCTGTCGCGCATGGCCGAGAATGCCCCGCTGA
CGCTGAAGGCGGCCAAGCTCGCCATCCGCGCCGCAGAGGGTGCGGGCGGCGGCGCCTTCGCGGAGGCCCGGCGTCTCGCC
GCGGCCGCCAATGCCAGCGCGGATTATCGTGAGGGCCGGCTCGCCTTTGCCGAGAAACGCGCCCCCCGCTTCAAGGGCGC
CTGA

Upstream 100 bases:

>100_bases
CGGGCATATGGAGGCGTCGGCACCGGGCAGGCATCGTCCCGGCGCCACCGCACGAAGCCCGCGCCCTGTCTTGGAGCGCG
GCCAGGACTGAGGGGGCACC

Downstream 100 bases:

>100_bases
CCGGCCCGCCCGCATCGCCGCGCATGCGGCCTGTGGGTTGTGCCACGGGAACGGGTTGCGCGCCGACGGCGGGTGCGGAT
ATGGTCCCGGCCCTGCGCTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTSAPAPASSAVFVTVEGGIARLVLSNPQRRNAISSGMWKTLADFAAEAGGRSDIRAAVIRGEGTLAFSGGADISDFDAA
RADASGAQTYDDVVEAACAAFQALPFPTLALVHGACVGAGAALSACCDLRLAATDAFFAIPAARLGLGYDPRGVSRLVRA
FGPQAARLMLFTAERLPAERAFALGAVDEIAAADAVDAAAERLLSRMAENAPLTLKAAKLAIRAAEGAGGGAFAEARRLA
AAANASADYREGRLAFAEKRAPRFKGA

Sequences:

>Translated_267_residues
MTSAPAPASSAVFVTVEGGIARLVLSNPQRRNAISSGMWKTLADFAAEAGGRSDIRAAVIRGEGTLAFSGGADISDFDAA
RADASGAQTYDDVVEAACAAFQALPFPTLALVHGACVGAGAALSACCDLRLAATDAFFAIPAARLGLGYDPRGVSRLVRA
FGPQAARLMLFTAERLPAERAFALGAVDEIAAADAVDAAAERLLSRMAENAPLTLKAAKLAIRAAEGAGGGAFAEARRLA
AAANASADYREGRLAFAEKRAPRFKGA
>Mature_266_residues
TSAPAPASSAVFVTVEGGIARLVLSNPQRRNAISSGMWKTLADFAAEAGGRSDIRAAVIRGEGTLAFSGGADISDFDAAR
ADASGAQTYDDVVEAACAAFQALPFPTLALVHGACVGAGAALSACCDLRLAATDAFFAIPAARLGLGYDPRGVSRLVRAF
GPQAARLMLFTAERLPAERAFALGAVDEIAAADAVDAAAERLLSRMAENAPLTLKAAKLAIRAAEGAGGGAFAEARRLAA
AANASADYREGRLAFAEKRAPRFKGA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=264, Percent_Identity=26.8939393939394, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI70995211, Length=202, Percent_Identity=28.7128712871287, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=27.5303643724696, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI157694516, Length=219, Percent_Identity=25.5707762557078, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI213417737, Length=219, Percent_Identity=25.5707762557078, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI68989263, Length=212, Percent_Identity=30.6603773584906, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=32.5581395348837, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082183, Length=220, Percent_Identity=28.1818181818182, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=28, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=30.0380228136882, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790281, Length=205, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788682, Length=157, Percent_Identity=30.5732484076433, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=30.241935483871, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=25.9109311740891, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=245, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=230, Percent_Identity=24.3478260869565, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=28.2258064516129, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=28.2258064516129, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922422, Length=264, Percent_Identity=25.3787878787879, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920382, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27186; Mature: 27055

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPAPASSAVFVTVEGGIARLVLSNPQRRNAISSGMWKTLADFAAEAGGRSDIRAAVI
CCCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RGEGTLAFSGGADISDFDAARADASGAQTYDDVVEAACAAFQALPFPTLALVHGACVGAG
ECCCEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
AALSACCDLRLAATDAFFAIPAARLGLGYDPRGVSRLVRAFGPQAARLMLFTAERLPAER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
AFALGAVDEIAAADAVDAAAERLLSRMAENAPLTLKAAKLAIRAAEGAGGGAFAEARRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHEEECCCCCCCHHHHHHHHH
AAANASADYREGRLAFAEKRAPRFKGA
HHHCCCCCHHCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSAPAPASSAVFVTVEGGIARLVLSNPQRRNAISSGMWKTLADFAAEAGGRSDIRAAVI
CCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RGEGTLAFSGGADISDFDAARADASGAQTYDDVVEAACAAFQALPFPTLALVHGACVGAG
ECCCEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
AALSACCDLRLAATDAFFAIPAARLGLGYDPRGVSRLVRAFGPQAARLMLFTAERLPAER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
AFALGAVDEIAAADAVDAAAERLLSRMAENAPLTLKAAKLAIRAAEGAGGGAFAEARRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHEEECCCCCCCHHHHHHHHH
AAANASADYREGRLAFAEKRAPRFKGA
HHHCCCCCHHCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]