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The map label for this gene is yibH [H]

Identifier: 157963470

GI number: 157963470

Start: 4449890

End: 4450921

Strand: Direct

Name: yibH [H]

Synonym: Spea_3658

Alternate gene names: 157963470

Gene position: 4449890-4450921 (Clockwise)

Preceding gene: 157963469

Following gene: 157963472

Centisome position: 86.0

GC content: 47.38

Gene sequence:

>1032_bases
ATGAAAGAGATAATGCTGCCGTATATTTTTATCGTATGGTTACTGTTTAAGTTCAAAGTAATCAAAGCCAGACCACGAAA
CTACTTTATTAGCGTGTTTGTAGGTTGTTTAATTGCACTCACGCTATTTTTGGCTCATCGCTTTTATTCTCCATCCGATC
TCACTAACTCGACGACAGTAAGGGCACCTCACGCGATCCTCTCACCCGCCTTTGGACAACAGATAGATAAAGTGGCAATC
GATCATAACCAGCAGGTAAACAAAGGCGACCTGCTATACACCTTGGTCGACGACAAGGTCAGCAGCGCTATCGATGAAAT
AAATGCACGCATCAATGAAGTCGAACGCAACATAGAAGCCACTGAGGTAAAGCTGGCGCAAGCAAAGCGTACTCATTTGC
GTAAAGCCAATCTTGGTGAGCATGTTAGCGAGCGAGACTTAGAGAACGCTGAAGATCACGTGGAAATTATTAAAGCAGAG
CTTAAGGTGCAACACGCCCAGCTAGAGGTGAAATATGCTCAGCTAAGAAAGCAAGAATTTGAGCTAAAAAGGCTTGAAGT
TCGGGCGCCATTCGACGGCATGGTGACCCATGTGTATATTGCCGATGGCTCAAGAGTCGGCGCTATGCACCTATGGGATA
CCGGCCGTAAATTTGTCGAGATGCGTATTCCCGATCAGTCATTTGCCTACATACAACCGGGTCAGTTTGCCGAGTTTTAT
ATCAACGCCTATCCAGGTCAGATATTTAGAGCCAGAGTCCACAGTAAGGTTGAAGCCACTGGTGAAGCTCAAGGCGACAT
CTTGCCTCGCGAGCAGATGGTATCACGTCATATCAACTTAGGCTCAATGCCCGTGGGCAGAACCGTGGTACTTGAAATAG
ATGACGACACCATGGCCATGTTGCCGATTGGTGCGACGGGCTCGGCTTGGATAAGTGCCGACAAGCCCTCTTCACTTCTA
GGCTTTCTCGATATCATTGGCGGGGCAACGGTGAGACTCACCGCAGTTAAGGCTTACCTTAACCCGTTATAA

Upstream 100 bases:

>100_bases
GTATGTTAGGCCTATTTTGGAAGCCTCTTTGGGTACTTGCTGTGATTGCCATCGTTACCGATTGGGACCGAGTACAGGAA
TGGATTAGAGGAACCCGCGC

Downstream 100 bases:

>100_bases
CTACCGTGATTGAGAATGCCGACTCCTATGCTTAGCACAGAAACAAAAAGCACTGCTTAGGCTGTGCTTTTTGTTCAATC
TCATTACGTGCCCAATTACG

Product: multidrug resistance efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKEIMLPYIFIVWLLFKFKVIKARPRNYFISVFVGCLIALTLFLAHRFYSPSDLTNSTTVRAPHAILSPAFGQQIDKVAI
DHNQQVNKGDLLYTLVDDKVSSAIDEINARINEVERNIEATEVKLAQAKRTHLRKANLGEHVSERDLENAEDHVEIIKAE
LKVQHAQLEVKYAQLRKQEFELKRLEVRAPFDGMVTHVYIADGSRVGAMHLWDTGRKFVEMRIPDQSFAYIQPGQFAEFY
INAYPGQIFRARVHSKVEATGEAQGDILPREQMVSRHINLGSMPVGRTVVLEIDDDTMAMLPIGATGSAWISADKPSSLL
GFLDIIGGATVRLTAVKAYLNPL

Sequences:

>Translated_343_residues
MKEIMLPYIFIVWLLFKFKVIKARPRNYFISVFVGCLIALTLFLAHRFYSPSDLTNSTTVRAPHAILSPAFGQQIDKVAI
DHNQQVNKGDLLYTLVDDKVSSAIDEINARINEVERNIEATEVKLAQAKRTHLRKANLGEHVSERDLENAEDHVEIIKAE
LKVQHAQLEVKYAQLRKQEFELKRLEVRAPFDGMVTHVYIADGSRVGAMHLWDTGRKFVEMRIPDQSFAYIQPGQFAEFY
INAYPGQIFRARVHSKVEATGEAQGDILPREQMVSRHINLGSMPVGRTVVLEIDDDTMAMLPIGATGSAWISADKPSSLL
GFLDIIGGATVRLTAVKAYLNPL
>Mature_343_residues
MKEIMLPYIFIVWLLFKFKVIKARPRNYFISVFVGCLIALTLFLAHRFYSPSDLTNSTTVRAPHAILSPAFGQQIDKVAI
DHNQQVNKGDLLYTLVDDKVSSAIDEINARINEVERNIEATEVKLAQAKRTHLRKANLGEHVSERDLENAEDHVEIIKAE
LKVQHAQLEVKYAQLRKQEFELKRLEVRAPFDGMVTHVYIADGSRVGAMHLWDTGRKFVEMRIPDQSFAYIQPGQFAEFY
INAYPGQIFRARVHSKVEATGEAQGDILPREQMVSRHINLGSMPVGRTVVLEIDDDTMAMLPIGATGSAWISADKPSSLL
GFLDIIGGATVRLTAVKAYLNPL

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=388, Percent_Identity=23.4536082474227, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081951, Length=212, Percent_Identity=27.8301886792453, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790012, Length=301, Percent_Identity=25.2491694352159, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38628; Mature: 38628

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIMLPYIFIVWLLFKFKVIKARPRNYFISVFVGCLIALTLFLAHRFYSPSDLTNSTTV
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
RAPHAILSPAFGQQIDKVAIDHNQQVNKGDLLYTLVDDKVSSAIDEINARINEVERNIEA
ECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCHH
TEVKLAQAKRTHLRKANLGEHVSERDLENAEDHVEIIKAELKVQHAQLEVKYAQLRKQEF
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKRLEVRAPFDGMVTHVYIADGSRVGAMHLWDTGRKFVEMRIPDQSFAYIQPGQFAEFY
HHHEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCEEEE
INAYPGQIFRARVHSKVEATGEAQGDILPREQMVSRHINLGSMPVGRTVVLEIDDDTMAM
EECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCEEE
LPIGATGSAWISADKPSSLLGFLDIIGGATVRLTAVKAYLNPL
EEECCCCCCEEECCCCHHHHHHHHHHCCCEEEEEEEHHHHCCC
>Mature Secondary Structure
MKEIMLPYIFIVWLLFKFKVIKARPRNYFISVFVGCLIALTLFLAHRFYSPSDLTNSTTV
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
RAPHAILSPAFGQQIDKVAIDHNQQVNKGDLLYTLVDDKVSSAIDEINARINEVERNIEA
ECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCHH
TEVKLAQAKRTHLRKANLGEHVSERDLENAEDHVEIIKAELKVQHAQLEVKYAQLRKQEF
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKRLEVRAPFDGMVTHVYIADGSRVGAMHLWDTGRKFVEMRIPDQSFAYIQPGQFAEFY
HHHEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCEEEE
INAYPGQIFRARVHSKVEATGEAQGDILPREQMVSRHINLGSMPVGRTVVLEIDDDTMAM
EECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCEEE
LPIGATGSAWISADKPSSLLGFLDIIGGATVRLTAVKAYLNPL
EEECCCCCCEEECCCCHHHHHHHHHHCCCEEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]