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The map label for this gene is sdsB [H]

Identifier: 157963243

GI number: 157963243

Start: 4191223

End: 4192170

Strand: Reverse

Name: sdsB [H]

Synonym: Spea_3429

Alternate gene names: 157963243

Gene position: 4192170-4191223 (Counterclockwise)

Preceding gene: 157963246

Following gene: 157963242

Centisome position: 81.01

GC content: 41.46

Gene sequence:

>948_bases
TTGGAGTTGAGGCATTTAAAGCACTTTTTAGTTCTAGCAAAGCTTAAACATTTTAATCGTGCTGCAGTGCAGCTTAACTT
GGCTCAACCTTCATTGTCTCGCAGCATTCAAAAGATGGAAGAGCGCCTAGGTGTTAAATTATTGGAGCGTAACTCCAAAT
CAGTTTCGTTAACTGAGTTTGGGGAGCTGGTGGTAAGGCAGGGGCAAAAAATTATCGATGATGTGGATCTCTTGTACAGA
GATATTCGTTCACTCAATGGCCTTGATGCAGGTGACATCTTGATTGGTTCAAGTCCGATTCCCTCAAATGCATTGCTAGG
AGCGGCTATTGGAAACTTTATTCGACTCTATCCACATATTAACGTTGAATTAATTGTTGAGTCACCCGCAGAGCTCTATG
AACGCTTAATCGGTGGTGGATTATCTATGTTTGTTGCTGAGACTAAAGCAACTGATTTTGATAAGCGAGATGAGCTCGCG
ACCTTACCTTTACCCGAGTACGATATTATTTTTTGTGTGAGGGCCGATCATCCCCTGATGATGAGTAAAGTGTTAATGCT
TGATGATTTAAGAGAATATCCTCTGGCCATTCCTCGCGCCATGCCTTCAAGTGTACAGACACAGTTTGGTGATCTGTTTG
ATAAAGATCGTCATGACTTTGGTGGCTTAGTTAAGTTTGATCAATTTTATCCAATTAAAGAGTCACTTCTAAATTGCAAT
ATGGTGGCCATTACGCCTGAGATCGCTGTGCGAAAAGAGCTAGCCGAGGGAAGGCTGGTGAGTTTGCCTGTATCGGATAT
GGTAAAGCTAACAAGTTGCTTTAGCATTGTTTACCTTAAGTCAAAAAGCCTAAGTCCTGTTACTACTGGTTTTATTGAAT
TTCTATTGAATTGTCATCCTCAAAAAAACATGCCAACTCGACAGCAGTCGGAGCTCGTTACCGTTTAA

Upstream 100 bases:

>100_bases
TTTGTTATTTCTTGAATACCAGAGAGTCATTATCCAGCAGAAGCTGAACAGATTAAGATAACAGGTCAGAAAGTAAACGG
ATAAGTAAGGAGAGTTTTCA

Downstream 100 bases:

>100_bases
CTCGTTAGATGAGTTTAGGCTTCGGGTATCTTTTGTATTGCTATCCATCTAATATCAAATGAAGGTAGATGCCACTTTTC
TCTTGATATTACAGACTTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MELRHLKHFLVLAKLKHFNRAAVQLNLAQPSLSRSIQKMEERLGVKLLERNSKSVSLTEFGELVVRQGQKIIDDVDLLYR
DIRSLNGLDAGDILIGSSPIPSNALLGAAIGNFIRLYPHINVELIVESPAELYERLIGGGLSMFVAETKATDFDKRDELA
TLPLPEYDIIFCVRADHPLMMSKVLMLDDLREYPLAIPRAMPSSVQTQFGDLFDKDRHDFGGLVKFDQFYPIKESLLNCN
MVAITPEIAVRKELAEGRLVSLPVSDMVKLTSCFSIVYLKSKSLSPVTTGFIEFLLNCHPQKNMPTRQQSELVTV

Sequences:

>Translated_315_residues
MELRHLKHFLVLAKLKHFNRAAVQLNLAQPSLSRSIQKMEERLGVKLLERNSKSVSLTEFGELVVRQGQKIIDDVDLLYR
DIRSLNGLDAGDILIGSSPIPSNALLGAAIGNFIRLYPHINVELIVESPAELYERLIGGGLSMFVAETKATDFDKRDELA
TLPLPEYDIIFCVRADHPLMMSKVLMLDDLREYPLAIPRAMPSSVQTQFGDLFDKDRHDFGGLVKFDQFYPIKESLLNCN
MVAITPEIAVRKELAEGRLVSLPVSDMVKLTSCFSIVYLKSKSLSPVTTGFIEFLLNCHPQKNMPTRQQSELVTV
>Mature_315_residues
MELRHLKHFLVLAKLKHFNRAAVQLNLAQPSLSRSIQKMEERLGVKLLERNSKSVSLTEFGELVVRQGQKIIDDVDLLYR
DIRSLNGLDAGDILIGSSPIPSNALLGAAIGNFIRLYPHINVELIVESPAELYERLIGGGLSMFVAETKATDFDKRDELA
TLPLPEYDIIFCVRADHPLMMSKVLMLDDLREYPLAIPRAMPSSVQTQFGDLFDKDRHDFGGLVKFDQFYPIKESLLNCN
MVAITPEIAVRKELAEGRLVSLPVSDMVKLTSCFSIVYLKSKSLSPVTTGFIEFLLNCHPQKNMPTRQQSELVTV

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=305, Percent_Identity=27.2131147540984, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787879, Length=310, Percent_Identity=28.0645161290323, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=25.4180602006689, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI157672245, Length=194, Percent_Identity=27.319587628866, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=26.962457337884, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=277, Percent_Identity=24.187725631769, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790399, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787589, Length=126, Percent_Identity=31.7460317460317, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=197, Percent_Identity=23.8578680203046, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367136, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789639, Length=165, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787128, Length=127, Percent_Identity=26.7716535433071, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788887, Length=183, Percent_Identity=28.9617486338798, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.1369863013699, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35399; Mature: 35399

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLKHFLVLAKLKHFNRAAVQLNLAQPSLSRSIQKMEERLGVKLLERNSKSVSLTEF
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEHHHH
GELVVRQGQKIIDDVDLLYRDIRSLNGLDAGDILIGSSPIPSNALLGAAIGNFIRLYPHI
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCC
NVELIVESPAELYERLIGGGLSMFVAETKATDFDKRDELATLPLPEYDIIFCVRADHPLM
CEEEEECCHHHHHHHHHCCCHHEEEECCCCCCCCCCCCEEECCCCCCCEEEEEECCCHHH
MSKVLMLDDLREYPLAIPRAMPSSVQTQFGDLFDKDRHDFGGLVKFDQFYPIKESLLNCN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHCCC
MVAITPEIAVRKELAEGRLVSLPVSDMVKLTSCFSIVYLKSKSLSPVTTGFIEFLLNCHP
EEEECCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCC
QKNMPTRQQSELVTV
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MELRHLKHFLVLAKLKHFNRAAVQLNLAQPSLSRSIQKMEERLGVKLLERNSKSVSLTEF
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCHHHHHCCCCEEEHHHH
GELVVRQGQKIIDDVDLLYRDIRSLNGLDAGDILIGSSPIPSNALLGAAIGNFIRLYPHI
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCC
NVELIVESPAELYERLIGGGLSMFVAETKATDFDKRDELATLPLPEYDIIFCVRADHPLM
CEEEEECCHHHHHHHHHCCCHHEEEECCCCCCCCCCCCEEECCCCCCCEEEEEECCCHHH
MSKVLMLDDLREYPLAIPRAMPSSVQTQFGDLFDKDRHDFGGLVKFDQFYPIKESLLNCN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHCCC
MVAITPEIAVRKELAEGRLVSLPVSDMVKLTSCFSIVYLKSKSLSPVTTGFIEFLLNCHP
EEEECCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCC
QKNMPTRQQSELVTV
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]