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The map label for this gene is nahR [H]

Identifier: 157963242

GI number: 157963242

Start: 4190213

End: 4191124

Strand: Reverse

Name: nahR [H]

Synonym: Spea_3428

Alternate gene names: 157963242

Gene position: 4191124-4190213 (Counterclockwise)

Preceding gene: 157963243

Following gene: 157963240

Centisome position: 80.99

GC content: 40.24

Gene sequence:

>912_bases
ATGAGCCAACTTGATCTCAATCTATTAAAAGTTTTTCGTGTACTCATCGAAGTAAAAAATACTCGCAAGGCTGCTGAAAT
ATTACATTTAAGCCAGCCCGCGGTGAGTCGTGCTCTCAGGCGTTTAAGAGATTATTTTGGTGATGAGTTGTTTGTAAGAA
GCGCTCACGGTCTCGAGCCCACCTCGAAGGCGCTGGTTATTGGTTCACGTTTACCTGAAGCCATGGATCAATTATTTGAA
GCGCTTAATGTTAAGGAGGAGTTCGAGCCTCAGTTTTATAGTGGTAAAGTCACAATTGCAGTGAATGGCTTTATTGCTCA
TTGGCTAGTGCCTCCGCTAATTAAAGCGTTAACCGAAAAAGCACCTAATATGGAAATTTACATGGCTAATTGGGAGGAGA
GTACATCGGATAAAATTATTAACGGTGAAATTCAACTGGCGATTAACTATTTTCCATTAGAGCTGACAAAGCAGCTAATC
CAAGAGAAGTTAGGCAGTGATGACTTCGTTGTACTCTGCCGTAAAGATCATCCATTCCAAAAGGAGGTGATAGGTGCTGA
AGACTTCCCGAAATATCCATTAGCCTCACATATTGTCCCGGGCTGGAACGAAACAAAAAACTTTACCGTTGAAGCGTTAA
AAAAATTGGGTTATAAGCCAAGAGTGCAGCTATCAAGTAGCAAAATGAATATTATCTTAAGCAGTTTAGAGCTGACCGAT
ATGTTATTACCCTGCTCGAAGTTATTAGCCAAAACATTATCTGATCGCTTTAGAATCATTGATATTGACCCTGAGCTAGA
ACAGCCATCGTCAGACTTTGCATTAATCTATGCTAATAAGTCGCGTCGTAATCCGTTGGATGAGTGGTTACAGCAGTGTG
TGATTGACTGTGTTAATAGTAAATTCAAATAA

Upstream 100 bases:

>100_bases
AACTCGTTAGATGAGTTTAGGCTTCGGGTATCTTTTGTATTGCTATCCATCTAATATCAAATGAAGGTAGATGCCACTTT
TCTCTTGATATTACAGACTT

Downstream 100 bases:

>100_bases
GTGTTAAGGGAGCTTGCGAGCATTAAGCATGTTCGCAAGCTAGTTGTTAGGAGATACTATAGACTTAGGCAAAAAGAACT
GTGTATAGATAACCTGCAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSQLDLNLLKVFRVLIEVKNTRKAAEILHLSQPAVSRALRRLRDYFGDELFVRSAHGLEPTSKALVIGSRLPEAMDQLFE
ALNVKEEFEPQFYSGKVTIAVNGFIAHWLVPPLIKALTEKAPNMEIYMANWEESTSDKIINGEIQLAINYFPLELTKQLI
QEKLGSDDFVVLCRKDHPFQKEVIGAEDFPKYPLASHIVPGWNETKNFTVEALKKLGYKPRVQLSSSKMNIILSSLELTD
MLLPCSKLLAKTLSDRFRIIDIDPELEQPSSDFALIYANKSRRNPLDEWLQQCVIDCVNSKFK

Sequences:

>Translated_303_residues
MSQLDLNLLKVFRVLIEVKNTRKAAEILHLSQPAVSRALRRLRDYFGDELFVRSAHGLEPTSKALVIGSRLPEAMDQLFE
ALNVKEEFEPQFYSGKVTIAVNGFIAHWLVPPLIKALTEKAPNMEIYMANWEESTSDKIINGEIQLAINYFPLELTKQLI
QEKLGSDDFVVLCRKDHPFQKEVIGAEDFPKYPLASHIVPGWNETKNFTVEALKKLGYKPRVQLSSSKMNIILSSLELTD
MLLPCSKLLAKTLSDRFRIIDIDPELEQPSSDFALIYANKSRRNPLDEWLQQCVIDCVNSKFK
>Mature_302_residues
SQLDLNLLKVFRVLIEVKNTRKAAEILHLSQPAVSRALRRLRDYFGDELFVRSAHGLEPTSKALVIGSRLPEAMDQLFEA
LNVKEEFEPQFYSGKVTIAVNGFIAHWLVPPLIKALTEKAPNMEIYMANWEESTSDKIINGEIQLAINYFPLELTKQLIQ
EKLGSDDFVVLCRKDHPFQKEVIGAEDFPKYPLASHIVPGWNETKNFTVEALKKLGYKPRVQLSSSKMNIILSSLELTDM
LLPCSKLLAKTLSDRFRIIDIDPELEQPSSDFALIYANKSRRNPLDEWLQQCVIDCVNSKFK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=23.2081911262799, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87081766, Length=313, Percent_Identity=23.3226837060703, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790147, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786820, Length=295, Percent_Identity=24.7457627118644, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=180, Percent_Identity=26.1111111111111, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34594; Mature: 34462

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDLNLLKVFRVLIEVKNTRKAAEILHLSQPAVSRALRRLRDYFGDELFVRSAHGLEP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
TSKALVIGSRLPEAMDQLFEALNVKEEFEPQFYSGKVTIAVNGFIAHWLVPPLIKALTEK
CCCEEEECCCCHHHHHHHHHHHCCHHHCCCCEECCEEEEEECHHHHHHHHHHHHHHHHCC
APNMEIYMANWEESTSDKIINGEIQLAINYFPLELTKQLIQEKLGSDDFVVLCRKDHPFQ
CCCCEEEEECCCCCCCCCEECCEEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCHH
KEVIGAEDFPKYPLASHIVPGWNETKNFTVEALKKLGYKPRVQLSSSKMNIILSSLELTD
HHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
MLLPCSKLLAKTLSDRFRIIDIDPELEQPSSDFALIYANKSRRNPLDEWLQQCVIDCVNS
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
KFK
CCC
>Mature Secondary Structure 
SQLDLNLLKVFRVLIEVKNTRKAAEILHLSQPAVSRALRRLRDYFGDELFVRSAHGLEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
TSKALVIGSRLPEAMDQLFEALNVKEEFEPQFYSGKVTIAVNGFIAHWLVPPLIKALTEK
CCCEEEECCCCHHHHHHHHHHHCCHHHCCCCEECCEEEEEECHHHHHHHHHHHHHHHHCC
APNMEIYMANWEESTSDKIINGEIQLAINYFPLELTKQLIQEKLGSDDFVVLCRKDHPFQ
CCCCEEEEECCCCCCCCCEECCEEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCHH
KEVIGAEDFPKYPLASHIVPGWNETKNFTVEALKKLGYKPRVQLSSSKMNIILSSLELTD
HHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
MLLPCSKLLAKTLSDRFRIIDIDPELEQPSSDFALIYANKSRRNPLDEWLQQCVIDCVNS
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
KFK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]