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The map label for this gene is yrkL [H]

Identifier: 157963218

GI number: 157963218

Start: 4158264

End: 4158839

Strand: Direct

Name: yrkL [H]

Synonym: Spea_3404

Alternate gene names: 157963218

Gene position: 4158264-4158839 (Clockwise)

Preceding gene: 157963217

Following gene: 157963219

Centisome position: 80.36

GC content: 43.58

Gene sequence:

>576_bases
ATGAAAGACGAAATGAGTAACCAGCTATTGATCTCGGGTCACCCCGATCTCAGCCGCTCCGTTGCTAACAGCCAAATCCT
TAAGCAACTACAAAATTGTAGTCAGATTAAGATCCATAGACTCGATGAGATATATCCAAATTATCGAATAGATGTCCAAG
CAGAGCAGGCGTTACTGACTCAAGCCGATATTATCGTGCTGCAGTTTCCCCTCTACTGGTCTACCTACCCAGCTTTAATG
AAGCTATGGTTCGATGAAGTCTTTACCTATAACTTCGCCTTCGGCCCTGAAGGAGACAAGCTCAAAAATAAGAAGGTGAT
CCTCTCTATTACCTGTGGTGCGACTGAAAACTCTTATCAACTAGGTGAGTTCAATTTCCTCCCCTTAGAGCAATATTTAC
AAGCCGCAGTGCACCCTATCAAGGCTGCACAGATGGAGATTGTCGATACAGTCATCACATTCGAAATGAACTCGACTCCA
TGTGAAGGTGGCGATCAAAGCACCGTCATGCAGTTAGCCCAACAGCATGTTGAGCGTTTAATCCATTTAATTAATCAACT
GAATGAATCAGCTTAA

Upstream 100 bases:

>100_bases
ATAAACCTATTGGGAGTCTCATTATCGACTGATGATGGGGTAAGCGCAGTAAGCATTTTAAGACATTTATTTATTACTAT
TATTTCAAGTGTATATATCA

Downstream 100 bases:

>100_bases
TTAGTCAATTTTATAATAGGTCTTTCCATCATGTTTCAATCCATATTAGGTATCGCAGCCCTACTTATCGTAGGCTACCT
TTTTTGTAATGCTAAAAAAC

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD(P); reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKDEMSNQLLISGHPDLSRSVANSQILKQLQNCSQIKIHRLDEIYPNYRIDVQAEQALLTQADIIVLQFPLYWSTYPALM
KLWFDEVFTYNFAFGPEGDKLKNKKVILSITCGATENSYQLGEFNFLPLEQYLQAAVHPIKAAQMEIVDTVITFEMNSTP
CEGGDQSTVMQLAQQHVERLIHLINQLNESA

Sequences:

>Translated_191_residues
MKDEMSNQLLISGHPDLSRSVANSQILKQLQNCSQIKIHRLDEIYPNYRIDVQAEQALLTQADIIVLQFPLYWSTYPALM
KLWFDEVFTYNFAFGPEGDKLKNKKVILSITCGATENSYQLGEFNFLPLEQYLQAAVHPIKAAQMEIVDTVITFEMNSTP
CEGGDQSTVMQLAQQHVERLIHLINQLNESA
>Mature_191_residues
MKDEMSNQLLISGHPDLSRSVANSQILKQLQNCSQIKIHRLDEIYPNYRIDVQAEQALLTQADIIVLQFPLYWSTYPALM
KLWFDEVFTYNFAFGPEGDKLKNKKVILSITCGATENSYQLGEFNFLPLEQYLQAAVHPIKAAQMEIVDTVITFEMNSTP
CEGGDQSTVMQLAQQHVERLIHLINQLNESA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Escherichia coli, GI1786231, Length=130, Percent_Identity=37.6923076923077, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1789750, Length=154, Percent_Identity=34.4155844155844, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21780; Mature: 21780

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDEMSNQLLISGHPDLSRSVANSQILKQLQNCSQIKIHRLDEIYPNYRIDVQAEQALLT
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCEEEEEHHHHHHH
QADIIVLQFPLYWSTYPALMKLWFDEVFTYNFAFGPEGDKLKNKKVILSITCGATENSYQ
HHCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
LGEFNFLPLEQYLQAAVHPIKAAQMEIVDTVITFEMNSTPCEGGDQSTVMQLAQQHVERL
CCCCCCCCHHHHHHHHHCHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
IHLINQLNESA
HHHHHHHCCCC
>Mature Secondary Structure
MKDEMSNQLLISGHPDLSRSVANSQILKQLQNCSQIKIHRLDEIYPNYRIDVQAEQALLT
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCEEEEEHHHHHHH
QADIIVLQFPLYWSTYPALMKLWFDEVFTYNFAFGPEGDKLKNKKVILSITCGATENSYQ
HHCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
LGEFNFLPLEQYLQAAVHPIKAAQMEIVDTVITFEMNSTPCEGGDQSTVMQLAQQHVERL
CCCCCCCCHHHHHHHHHCHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
IHLINQLNESA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]