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The map label for this gene is ompC [H]

Identifier: 157963181

GI number: 157963181

Start: 4111275

End: 4112432

Strand: Direct

Name: ompC [H]

Synonym: Spea_3366

Alternate gene names: 157963181

Gene position: 4111275-4112432 (Clockwise)

Preceding gene: 157963174

Following gene: 157963183

Centisome position: 79.45

GC content: 47.5

Gene sequence:

>1158_bases
ATGAATAAGAAACTGTTGGCGCTTTTAATCCCGTCGATTTTAATAGCAGGTTCTGCGCAGGCCGTTGAGATCTACAATGA
TCAAACGAACAGCATAAACATGATGGGTTGGTTAGGCTTTGCTGCCATTAATGACACTCACGACACTGCCGTCGTCGATA
ACTTCTCTCGTGTAGGCTTTCGCTTCGATCGCCAAGAGAAGAACGGCTGGCGCAGCTTTGCTCATACCGAATGGGGCATT
AACATGGTCACCAGCGATGACTCGCTAAGCTACAGCGGCGGTCAACTCGGTGCAGAGAAAAACTCTGACTTCTTATTCAA
CCGTTTAGGCTATGTGGGTTTAGCAAACGACAAATGGGGAAGCTTAACTTTTGGTAAGCAGTGGGGCGTATACTACGATG
TGGCCTACACCACCGACGTACTTAACGTCTATACGGGCTACTCTGTTGGAGCCTACACCTTTGGTGATGGCGGCCTAACC
GGTGCTGGTCGCGCAGACTCAGCCTTTGTATACCGTAACTCATTTGGCAACTTGAGCATTGCACTGCAGTATGCCGCTAA
GCAAAATGGTGATGTAGCACTGTATGACAAAGATGGCATCGCACTCGACGACGGTTCACACGTTGAATTTGATACCAGTT
ATGGCGCTAGCTTAACCTACCACTTTACCGATAAATTCAAGGTACTTGCAGGCATTAACCGAGGTGACTTCACTGGTGAA
CTTGCAGGTGAGCGCGTTGACGATACTAACGAGATCATAGGTGTGGGCGCACAATATGGTTCTTTCTACCAGTATGCACC
TAATCGCGAAGCCGATGGCTTCTATGTGGGTTTCAACGCTCATAAGAGTAAGCAAAATGAGCTAGTAGCGGGCGAGCTAT
ATGACTCGACTGGCAGTGAGTTTTTGATTGCCTATCAGTATGAGAATGGCTTTGTACCTAGCTTCCTACTGTCTTACCAA
GACTTAGATACCGATGCTTCGACAACGATTCAAGGTGACTGGACCCGCCAATTTGCGGTACTCGGTCTACATTACCGTTA
TAGCAACGACACAGTGATGTTTGCCGAAGCAAAAATCGATTTCAGCGACATGGACGATAAGAGCTTTGAAAACCTTCAGG
ACAATAGCTACGCTGTCGGTATTCGCTACTTCTTCTAG

Upstream 100 bases:

>100_bases
CCTATTTAGCTCCCTTGGCACGTTAGCTGCTCTGTAAGGCGTAATTGGTAAAAACCAATCATTGATTAGCTTTAACAAAA
TAAAAAATAGGGAAAATGAC

Downstream 100 bases:

>100_bases
TTATAGCGGATTTGTTTTCACAAAGCAGTGAGAACTACCCCTTAGTTCGACTCAATCCAGGATAGATTGAGTCACTACTT
TCTCGTTTAATTAGCTCCCT

Product: porin

Products: NA

Alternate protein names: Porin ompC; Porin ompk36 [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNKKLLALLIPSILIAGSAQAVEIYNDQTNSINMMGWLGFAAINDTHDTAVVDNFSRVGFRFDRQEKNGWRSFAHTEWGI
NMVTSDDSLSYSGGQLGAEKNSDFLFNRLGYVGLANDKWGSLTFGKQWGVYYDVAYTTDVLNVYTGYSVGAYTFGDGGLT
GAGRADSAFVYRNSFGNLSIALQYAAKQNGDVALYDKDGIALDDGSHVEFDTSYGASLTYHFTDKFKVLAGINRGDFTGE
LAGERVDDTNEIIGVGAQYGSFYQYAPNREADGFYVGFNAHKSKQNELVAGELYDSTGSEFLIAYQYENGFVPSFLLSYQ
DLDTDASTTIQGDWTRQFAVLGLHYRYSNDTVMFAEAKIDFSDMDDKSFENLQDNSYAVGIRYFF

Sequences:

>Translated_385_residues
MNKKLLALLIPSILIAGSAQAVEIYNDQTNSINMMGWLGFAAINDTHDTAVVDNFSRVGFRFDRQEKNGWRSFAHTEWGI
NMVTSDDSLSYSGGQLGAEKNSDFLFNRLGYVGLANDKWGSLTFGKQWGVYYDVAYTTDVLNVYTGYSVGAYTFGDGGLT
GAGRADSAFVYRNSFGNLSIALQYAAKQNGDVALYDKDGIALDDGSHVEFDTSYGASLTYHFTDKFKVLAGINRGDFTGE
LAGERVDDTNEIIGVGAQYGSFYQYAPNREADGFYVGFNAHKSKQNELVAGELYDSTGSEFLIAYQYENGFVPSFLLSYQ
DLDTDASTTIQGDWTRQFAVLGLHYRYSNDTVMFAEAKIDFSDMDDKSFENLQDNSYAVGIRYFF
>Mature_385_residues
MNKKLLALLIPSILIAGSAQAVEIYNDQTNSINMMGWLGFAAINDTHDTAVVDNFSRVGFRFDRQEKNGWRSFAHTEWGI
NMVTSDDSLSYSGGQLGAEKNSDFLFNRLGYVGLANDKWGSLTFGKQWGVYYDVAYTTDVLNVYTGYSVGAYTFGDGGLT
GAGRADSAFVYRNSFGNLSIALQYAAKQNGDVALYDKDGIALDDGSHVEFDTSYGASLTYHFTDKFKVLAGINRGDFTGE
LAGERVDDTNEIIGVGAQYGSFYQYAPNREADGFYVGFNAHKSKQNELVAGELYDSTGSEFLIAYQYENGFVPSFLLSYQ
DLDTDASTTIQGDWTRQFAVLGLHYRYSNDTVMFAEAKIDFSDMDDKSFENLQDNSYAVGIRYFF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. In K.pneumoniae it has been shown to bind the C1Q component and activate the classical pathway of the complement system [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786436, Length=401, Percent_Identity=26.1845386533666, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 42694; Mature: 42694

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLLALLIPSILIAGSAQAVEIYNDQTNSINMMGWLGFAAINDTHDTAVVDNFSRVGF
CCCEEHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECCCCCCHHHCCHHHHCE
RFDRQEKNGWRSFAHTEWGINMVTSDDSLSYSGGQLGAEKNSDFLFNRLGYVGLANDKWG
EEECCCCCCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCC
SLTFGKQWGVYYDVAYTTDVLNVYTGYSVGAYTFGDGGLTGAGRADSAFVYRNSFGNLSI
CEEECCCCCEEEEEEEHEEEHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEE
ALQYAAKQNGDVALYDKDGIALDDGSHVEFDTSYGASLTYHFTDKFKVLAGINRGDFTGE
EEEEECCCCCCEEEEECCCEEECCCCEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCC
LAGERVDDTNEIIGVGAQYGSFYQYAPNREADGFYVGFNAHKSKQNELVAGELYDSTGSE
CCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCE
FLIAYQYENGFVPSFLLSYQDLDTDASTTIQGDWTRQFAVLGLHYRYSNDTVMFAEAKID
EEEEEEECCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEEEEEEEEECCCEEEEEEEEEC
FSDMDDKSFENLQDNSYAVGIRYFF
CCCCCCCHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure
MNKKLLALLIPSILIAGSAQAVEIYNDQTNSINMMGWLGFAAINDTHDTAVVDNFSRVGF
CCCEEHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECCCCCCHHHCCHHHHCE
RFDRQEKNGWRSFAHTEWGINMVTSDDSLSYSGGQLGAEKNSDFLFNRLGYVGLANDKWG
EEECCCCCCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCC
SLTFGKQWGVYYDVAYTTDVLNVYTGYSVGAYTFGDGGLTGAGRADSAFVYRNSFGNLSI
CEEECCCCCEEEEEEEHEEEHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCEEE
ALQYAAKQNGDVALYDKDGIALDDGSHVEFDTSYGASLTYHFTDKFKVLAGINRGDFTGE
EEEEECCCCCCEEEEECCCEEECCCCEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCC
LAGERVDDTNEIIGVGAQYGSFYQYAPNREADGFYVGFNAHKSKQNELVAGELYDSTGSE
CCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCE
FLIAYQYENGFVPSFLLSYQDLDTDASTTIQGDWTRQFAVLGLHYRYSNDTVMFAEAKID
EEEEEEECCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEEEEEEEEECCCEEEEEEEEEC
FSDMDDKSFENLQDNSYAVGIRYFF
CCCCCCCHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868262; 10196126 [H]