Click here to switch to the map view.

The map label for this gene is torC [H]

Identifier: 157963158

GI number: 157963158

Start: 4083472

End: 4084650

Strand: Direct

Name: torC [H]

Synonym: Spea_3342

Alternate gene names: 157963158

Gene position: 4083472-4084650 (Clockwise)

Preceding gene: 157963157

Following gene: 157963159

Centisome position: 78.91

GC content: 44.95

Gene sequence:

>1179_bases
ATGAGATGGTTACTTAACATCTGGCGCACACTGACTAAACCAGCTAAATACCTAACCTTAGGAAGTATTGGTATTTCTGC
CTTTCTAATGGGAATTATCTTCTGGGGTGGCTTTAACACTGCACTTGAAGCAACGAATACAGAAGAGTTCTGTATCAGCT
GTCACAGTATGGAAAGCAAGCCTTACCAAGAGCTCCAACAGACTGTACATTTTTCAAACCATTCAGGTGTGCGTGCAACT
TGCCCAGACTGTCACGTACCGCATAACTATGGCCGTAAGATAGCGCGTAAGTTAGAAGCTTCTCACGACGTATACGGTTG
GTTGTTTAACACCGTCAATACACCTGAGAAGTTTGAAGCTAAGCGTCTTGAAATGGCAAGCCGTGAGTGGAAACGTTTTG
ACCGTGATAAGTCTGCAGCATGTAAAAACTGTCACCAGTACGACTCTATGAAGTGGGACAGCATGTCTAAGCTTGCAGTT
AAGCAAATGAAGCGCGCTGCTGAGTTAGATCAAAGCTGTGTGGATTGCCACAAAGGTATTGCTCACAAGCTACCAGAAAT
GGGTACCGCTCGTGCTCCAGAGTTGATTGCCGAAGTGGGTCGTGGCGTAAGTGGTGTTCAAGTGGGTCAAACTTACTTCA
CAGCATTAACCAAGCCATTATTCTTCAACGATAAAACTGACGTTGAAGCCGGCACATTAAACATTGCGACTAAGGTGAAA
ATCTTAGAAGTAAAAGGTAACCGTGCCAAGATTGGTATCGATGGCTGGAGAAAGAAAATCGGTGCAGGCCGCGTGATCTA
CTATGACTTTGGCTTAAACATTCTTTCGGCTCAGTTAACTAAAGACGCTGCGCTAGAAGAAGGTGTGATTAAGACATTCG
AAGAGAAAGAAGATCCAATGACAGGCCTTAAGTGGCAGCGTGTAGAAGCGGACATTTGGACGGAAACTGACTACTTGCTA
ACGGATCTACAACCACTATGGGATTACGCTCGTAGTACATACAGCACAGCATGTAGCGTATGTCACACCCAGCCAGCTGA
AGCACACTTTGACGCCAACACATGGCCAGGTATGTTCCAAGGCATGATCGCATTCGTCAACATGGATCAAGATACCCAAG
CTTTGGTACAGAAATATTTACAAGAGCATTCATCAACTTTCGATAAGTCGGCTCACTAA

Upstream 100 bases:

>100_bases
AGCGTATACGGTTTGATTATCTGGATTTCTCTTACATTTAGTGGCGTTGCGTCTCACTAATTTCAATAACACATTTTAAA
TTTATTACGAGGATGCCGTT

Downstream 100 bases:

>100_bases
TAGGACATAGCGTAATGAACAGAAGAGACTTTCTAAAAGGCTTAGTTGGAACATCTTATGTCGTACTTAGCGGTTCATCA
GTACTTGCACCGCTAAACGC

Product: trimethylamine-N-oxide reductase c-type cytochrome TorC

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRWLLNIWRTLTKPAKYLTLGSIGISAFLMGIIFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHFSNHSGVRAT
CPDCHVPHNYGRKIARKLEASHDVYGWLFNTVNTPEKFEAKRLEMASREWKRFDRDKSAACKNCHQYDSMKWDSMSKLAV
KQMKRAAELDQSCVDCHKGIAHKLPEMGTARAPELIAEVGRGVSGVQVGQTYFTALTKPLFFNDKTDVEAGTLNIATKVK
ILEVKGNRAKIGIDGWRKKIGAGRVIYYDFGLNILSAQLTKDAALEEGVIKTFEEKEDPMTGLKWQRVEADIWTETDYLL
TDLQPLWDYARSTYSTACSVCHTQPAEAHFDANTWPGMFQGMIAFVNMDQDTQALVQKYLQEHSSTFDKSAH

Sequences:

>Translated_392_residues
MRWLLNIWRTLTKPAKYLTLGSIGISAFLMGIIFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHFSNHSGVRAT
CPDCHVPHNYGRKIARKLEASHDVYGWLFNTVNTPEKFEAKRLEMASREWKRFDRDKSAACKNCHQYDSMKWDSMSKLAV
KQMKRAAELDQSCVDCHKGIAHKLPEMGTARAPELIAEVGRGVSGVQVGQTYFTALTKPLFFNDKTDVEAGTLNIATKVK
ILEVKGNRAKIGIDGWRKKIGAGRVIYYDFGLNILSAQLTKDAALEEGVIKTFEEKEDPMTGLKWQRVEADIWTETDYLL
TDLQPLWDYARSTYSTACSVCHTQPAEAHFDANTWPGMFQGMIAFVNMDQDTQALVQKYLQEHSSTFDKSAH
>Mature_392_residues
MRWLLNIWRTLTKPAKYLTLGSIGISAFLMGIIFWGGFNTALEATNTEEFCISCHSMESKPYQELQQTVHFSNHSGVRAT
CPDCHVPHNYGRKIARKLEASHDVYGWLFNTVNTPEKFEAKRLEMASREWKRFDRDKSAACKNCHQYDSMKWDSMSKLAV
KQMKRAAELDQSCVDCHKGIAHKLPEMGTARAPELIAEVGRGVSGVQVGQTYFTALTKPLFFNDKTDVEAGTLNIATKVK
ILEVKGNRAKIGIDGWRKKIGAGRVIYYDFGLNILSAQLTKDAALEEGVIKTFEEKEDPMTGLKWQRVEADIWTETDYLL
TDLQPLWDYARSTYSTACSVCHTQPAEAHFDANTWPGMFQGMIAFVNMDQDTQALVQKYLQEHSSTFDKSAH

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=396, Percent_Identity=38.3838383838384, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1788530, Length=180, Percent_Identity=51.6666666666667, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1788181, Length=345, Percent_Identity=33.6231884057971, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44406; Mature: 44406

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLLNIWRTLTKPAKYLTLGSIGISAFLMGIIFWGGFNTALEATNTEEFCISCHSMESK
CHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCC
PYQELQQTVHFSNHSGVRATCPDCHVPHNYGRKIARKLEASHDVYGWLFNTVNTPEKFEA
HHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHH
KRLEMASREWKRFDRDKSAACKNCHQYDSMKWDSMSKLAVKQMKRAAELDQSCVDCHKGI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHKLPEMGTARAPELIAEVGRGVSGVQVGQTYFTALTKPLFFNDKTDVEAGTLNIATKVK
HHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEEEE
ILEVKGNRAKIGIDGWRKKIGAGRVIYYDFGLNILSAQLTKDAALEEGVIKTFEEKEDPM
EEEECCCEEEECHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGLKWQRVEADIWTETDYLLTDLQPLWDYARSTYSTACSVCHTQPAEAHFDANTWPGMFQ
CCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
GMIAFVNMDQDTQALVQKYLQEHSSTFDKSAH
HHHHEECCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRWLLNIWRTLTKPAKYLTLGSIGISAFLMGIIFWGGFNTALEATNTEEFCISCHSMESK
CHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCCC
PYQELQQTVHFSNHSGVRATCPDCHVPHNYGRKIARKLEASHDVYGWLFNTVNTPEKFEA
HHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHH
KRLEMASREWKRFDRDKSAACKNCHQYDSMKWDSMSKLAVKQMKRAAELDQSCVDCHKGI
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHKLPEMGTARAPELIAEVGRGVSGVQVGQTYFTALTKPLFFNDKTDVEAGTLNIATKVK
HHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEEEE
ILEVKGNRAKIGIDGWRKKIGAGRVIYYDFGLNILSAQLTKDAALEEGVIKTFEEKEDPM
EEEECCCEEEECHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGLKWQRVEADIWTETDYLLTDLQPLWDYARSTYSTACSVCHTQPAEAHFDANTWPGMFQ
CCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
GMIAFVNMDQDTQALVQKYLQEHSSTFDKSAH
HHHHEECCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]