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The map label for this gene is corC [H]

Identifier: 157962957

GI number: 157962957

Start: 3844588

End: 3845469

Strand: Direct

Name: corC [H]

Synonym: Spea_3140

Alternate gene names: 157962957

Gene position: 3844588-3845469 (Clockwise)

Preceding gene: 157962956

Following gene: 157962958

Centisome position: 74.3

GC content: 44.44

Gene sequence:

>882_bases
ATGAGTGACGATATCCCACCGAGTACTAACGCCTCTAAGAAGGGCTGGTTAGACAAAGTAAGTCAGTTGTTCCAGGGCGA
ACCGAAAAATCGCGAAGATTTAGTAGACGTAATTCACGATGCAGAAATGCGAGAAGTGATAAGCGTAGACACACGCGAAA
TGATTAAAGGTGTTTTAGAAGTCTCCGATCTACGTGTACGGGATATTATGATCCCACGCGCACAGATTGTGGCTATCCAA
ATTGACGACTCTGTAGAAGAAGTTTTATCTACCGTGATCGGTTCAGCACACTCCCGTTTTCCAGTAGTCAATGAAGACAA
AGATCATGTCGAAGGCATTTTGCTTGCGAAAGACTTGCTTCAGTATGGCTTTAAAAACAACGAAGAACCATTCGAATTAC
GTCAAGTAATCCGACCTGCTGTCGTTGTTCCTGAGAGTAAACGTGTTGATGTGTTACTAAAGGAATTCCGCTCTCAGCGT
TACCATATGGCGATTGTTGTCGATGAGTACGGCGGAGTGTCGGGCCTAGTGACGATTGAGGATATTCTCGAAGAGATCGT
AGGTGATATCGAAGACGAGTTTGACCATGACTCTGCAGAAGAGACTGAAATCAAACAAGTCAGCAAGCAAGTATTCATGG
TGAAAGCACTCACTCCAATCGATGACTTCAATGAAGCATTCGGTACTGAGTTTAGTGACGAAGAATTCGATACCGTTGGT
GGTATGGTGTCCCATGCATTTGGCCATCTACCAGAGCGTGACGAAAAGGTCATGATCCAAGATATCGAGTTTAAAGTGGT
TAACGCCGATACTCGTCGCTTGATCCAACTTAGAGTTAAACTCCCTGGTAACGGTCATAGCAATGATGAGACTGTTGCTT
AG

Upstream 100 bases:

>100_bases
TGAAGAGATGGAGTCATTAGAGACCCAACTGATTGAAAGCCTTGGTTATATTAATCCTTACAAGGAGCAATAATTGGCTC
AATAGAGCCAGGAAAACACT

Downstream 100 bases:

>100_bases
CAACTAACTTACGTTATCACGACCCAATGATGAGGCTGTATGCTGAATAAATTTCGGGCATTAGCCCATCATCCGCGTTC
GAAACTGGTGCTGGCCTACG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSDDIPPSTNASKKGWLDKVSQLFQGEPKNREDLVDVIHDAEMREVISVDTREMIKGVLEVSDLRVRDIMIPRAQIVAIQ
IDDSVEEVLSTVIGSAHSRFPVVNEDKDHVEGILLAKDLLQYGFKNNEEPFELRQVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGDIEDEFDHDSAEETEIKQVSKQVFMVKALTPIDDFNEAFGTEFSDEEFDTVG
GMVSHAFGHLPERDEKVMIQDIEFKVVNADTRRLIQLRVKLPGNGHSNDETVA

Sequences:

>Translated_293_residues
MSDDIPPSTNASKKGWLDKVSQLFQGEPKNREDLVDVIHDAEMREVISVDTREMIKGVLEVSDLRVRDIMIPRAQIVAIQ
IDDSVEEVLSTVIGSAHSRFPVVNEDKDHVEGILLAKDLLQYGFKNNEEPFELRQVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGDIEDEFDHDSAEETEIKQVSKQVFMVKALTPIDDFNEAFGTEFSDEEFDTVG
GMVSHAFGHLPERDEKVMIQDIEFKVVNADTRRLIQLRVKLPGNGHSNDETVA
>Mature_292_residues
SDDIPPSTNASKKGWLDKVSQLFQGEPKNREDLVDVIHDAEMREVISVDTREMIKGVLEVSDLRVRDIMIPRAQIVAIQI
DDSVEEVLSTVIGSAHSRFPVVNEDKDHVEGILLAKDLLQYGFKNNEEPFELRQVIRPAVVVPESKRVDVLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEEIVGDIEDEFDHDSAEETEIKQVSKQVFMVKALTPIDDFNEAFGTEFSDEEFDTVGG
MVSHAFGHLPERDEKVMIQDIEFKVVNADTRRLIQLRVKLPGNGHSNDETVA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=192, Percent_Identity=32.8125, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI94681046, Length=180, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=285, Percent_Identity=56.8421052631579, Blast_Score=310, Evalue=8e-86,
Organism=Escherichia coli, GI145693175, Length=253, Percent_Identity=26.8774703557312, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790664, Length=250, Percent_Identity=26, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082033, Length=267, Percent_Identity=25.8426966292135, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=31.2757201646091, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33086; Mature: 32954

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDIPPSTNASKKGWLDKVSQLFQGEPKNREDLVDVIHDAEMREVISVDTREMIKGVLE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VSDLRVRDIMIPRAQIVAIQIDDSVEEVLSTVIGSAHSRFPVVNEDKDHVEGILLAKDLL
HHCCHHHHEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QYGFKNNEEPFELRQVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
HHCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDHDSAEETEIKQVSKQVFMVKALTPIDDFNEAFGTEFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHH
GMVSHAFGHLPERDEKVMIQDIEFKVVNADTRRLIQLRVKLPGNGHSNDETVA
HHHHHHHCCCCCCCCEEEEEEEEEEEECCHHHEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SDDIPPSTNASKKGWLDKVSQLFQGEPKNREDLVDVIHDAEMREVISVDTREMIKGVLE
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VSDLRVRDIMIPRAQIVAIQIDDSVEEVLSTVIGSAHSRFPVVNEDKDHVEGILLAKDLL
HHCCHHHHEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
QYGFKNNEEPFELRQVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
HHCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDHDSAEETEIKQVSKQVFMVKALTPIDDFNEAFGTEFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHH
GMVSHAFGHLPERDEKVMIQDIEFKVVNADTRRLIQLRVKLPGNGHSNDETVA
HHHHHHHCCCCCCCCEEEEEEEEEEEECCHHHEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]