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The map label for this gene is sapD [H]

Identifier: 157962495

GI number: 157962495

Start: 3257320

End: 3258327

Strand: Direct

Name: sapD [H]

Synonym: Spea_2674

Alternate gene names: 157962495

Gene position: 3257320-3258327 (Clockwise)

Preceding gene: 157962494

Following gene: 157962496

Centisome position: 62.95

GC content: 48.12

Gene sequence:

>1008_bases
ATGCCATTACTCGATATTCGTAATCTCACCATTGAACTCGATACCCCCCATGGACGAGTCAAGGCGCTAGAACGTGTAAG
CTTAACCATTAATCCTGGTGAACTGCATGGTCTAGTGGGTGAATCAGGTTCAGGCCGTACGCTATTAGCCCGTGCTATTT
TAGGTGTGCCGGGTCATAACTGGACAATTACCGCCGATCGCATGATGTGGGACGGTCAAAATTTAATGGATATGTCGGCT
AAGCAGCGACGTAACTTAATGGGCAGTGAAATAGCCGTTATTTTCCAAGATCCTACAGGCAGCTTAGATCCAGCTATCAC
AGTTGGCAGCCAGCTTATCGAAGCTATGCCTAAAGATAAAAAAATCTCATTTTGGAAACGTAACAAGGCTCGAAAAGCTG
TGGCTCAAAAGTGGCTGCATAAGGTCGGTATCAAGAACACTGAAGAAGTAATGAGCAGTTACGCGTGGGAGCTCTCCGCT
GGTGAATGCCAGAAAGTAATGATTGCCATGGCCATTGCCAATCAGCCACGCCTGTTGATTGCCGACGAGCCAACCGACTC
GATGGAACTCAGTACTCAGGCACAGATCTTTAGGCTGCTGGGTAAACTTAACCAGCTACACAGCGTATCAATTTTGTTGA
TTAGCCATGAACTAGAAACCTTATCAGGTTGGTGCGACCAACTCACCGTTTTATATTGCGGCCAAGTCATGGAGTCCGGT
CCAACGGCCGAAGTGCTTGAACAACCGTTTCACCCCTATACCAAAGCATTACTGGATAATATGCCTGACTACTCAGGCCG
ACTTACCCATAAATCGGTGATGCAAACCTTGCCAGGATCAGCACCAGCTCTGCAGCATCTCCCTATCGGCTGCCGCCTGG
GTCCCCGCTGTCCACAGGCGCAAAAACAATGCGTCAGTAAACCAAGCCTATGCCATAAGAAAGGCCGCTATTTTGCTTGC
CATTTCCCATACAACAGTGAGCCATGTAATGACGACTCCACTTCTTAA

Upstream 100 bases:

>100_bases
GTAACCATCCCTGGTGTTGCCATTTTATGTAGCGTACTGGCTATCAACTTAGTTGGTGACGGTTTGAGATCGGCGTTATC
GCCCATCAGAAATTAATACT

Downstream 100 bases:

>100_bases
AGTTACAGATCTCAGCAAGAGTTATTATGCTGGCTACAAACGTTTTAAGCGTCAATATAACAAGGCGCTTTCACCGGTAT
CGTTTGAATTAAACCAAGGT

Product: oligopeptide/dipeptide ABC transporter ATPase

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPLLDIRNLTIELDTPHGRVKALERVSLTINPGELHGLVGESGSGRTLLARAILGVPGHNWTITADRMMWDGQNLMDMSA
KQRRNLMGSEIAVIFQDPTGSLDPAITVGSQLIEAMPKDKKISFWKRNKARKAVAQKWLHKVGIKNTEEVMSSYAWELSA
GECQKVMIAMAIANQPRLLIADEPTDSMELSTQAQIFRLLGKLNQLHSVSILLISHELETLSGWCDQLTVLYCGQVMESG
PTAEVLEQPFHPYTKALLDNMPDYSGRLTHKSVMQTLPGSAPALQHLPIGCRLGPRCPQAQKQCVSKPSLCHKKGRYFAC
HFPYNSEPCNDDSTS

Sequences:

>Translated_335_residues
MPLLDIRNLTIELDTPHGRVKALERVSLTINPGELHGLVGESGSGRTLLARAILGVPGHNWTITADRMMWDGQNLMDMSA
KQRRNLMGSEIAVIFQDPTGSLDPAITVGSQLIEAMPKDKKISFWKRNKARKAVAQKWLHKVGIKNTEEVMSSYAWELSA
GECQKVMIAMAIANQPRLLIADEPTDSMELSTQAQIFRLLGKLNQLHSVSILLISHELETLSGWCDQLTVLYCGQVMESG
PTAEVLEQPFHPYTKALLDNMPDYSGRLTHKSVMQTLPGSAPALQHLPIGCRLGPRCPQAQKQCVSKPSLCHKKGRYFAC
HFPYNSEPCNDDSTS
>Mature_334_residues
PLLDIRNLTIELDTPHGRVKALERVSLTINPGELHGLVGESGSGRTLLARAILGVPGHNWTITADRMMWDGQNLMDMSAK
QRRNLMGSEIAVIFQDPTGSLDPAITVGSQLIEAMPKDKKISFWKRNKARKAVAQKWLHKVGIKNTEEVMSSYAWELSAG
ECQKVMIAMAIANQPRLLIADEPTDSMELSTQAQIFRLLGKLNQLHSVSILLISHELETLSGWCDQLTVLYCGQVMESGP
TAEVLEQPFHPYTKALLDNMPDYSGRLTHKSVMQTLPGSAPALQHLPIGCRLGPRCPQAQKQCVSKPSLCHKKGRYFACH
FPYNSEPCNDDSTS

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=55.1829268292683, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1789963, Length=327, Percent_Identity=38.5321100917431, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1787759, Length=325, Percent_Identity=38.1538461538462, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI48994883, Length=322, Percent_Identity=36.9565217391304, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787500, Length=322, Percent_Identity=33.2298136645963, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI145693107, Length=266, Percent_Identity=33.0827067669173, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787758, Length=306, Percent_Identity=33.0065359477124, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788506, Length=261, Percent_Identity=35.632183908046, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=30.6188925081433, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI48994997, Length=261, Percent_Identity=32.5670498084291, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789890, Length=257, Percent_Identity=29.1828793774319, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789891, Length=251, Percent_Identity=31.0756972111554, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786398, Length=288, Percent_Identity=28.4722222222222, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787547, Length=263, Percent_Identity=27.7566539923954, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081791, Length=272, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081834, Length=207, Percent_Identity=31.8840579710145, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787792, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788225, Length=267, Percent_Identity=25.8426966292135, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789032, Length=254, Percent_Identity=27.9527559055118, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786563, Length=238, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787370, Length=261, Percent_Identity=23.7547892720307, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787712, Length=255, Percent_Identity=24.3137254901961, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790190, Length=238, Percent_Identity=26.890756302521, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786703, Length=222, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790162, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48995001, Length=236, Percent_Identity=28.8135593220339, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=27.6018099547511, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=26.2931034482759, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788761, Length=247, Percent_Identity=24.6963562753036, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786345, Length=243, Percent_Identity=25.5144032921811, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790739, Length=250, Percent_Identity=26, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790525, Length=233, Percent_Identity=29.1845493562232, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789672, Length=246, Percent_Identity=23.9837398373984, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788472, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789991, Length=233, Percent_Identity=24.8927038626609, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787089, Length=243, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788210, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788644, Length=259, Percent_Identity=26.2548262548263, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788450, Length=241, Percent_Identity=21.9917012448133, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=262, Percent_Identity=20.9923664122137, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=258, Percent_Identity=23.2558139534884, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786803, Length=249, Percent_Identity=23.6947791164659, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790544, Length=246, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787112, Length=257, Percent_Identity=25.2918287937743, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789586, Length=263, Percent_Identity=24.3346007604563, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=265, Percent_Identity=22.6415094339623, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788897, Length=223, Percent_Identity=27.3542600896861, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789593, Length=227, Percent_Identity=22.4669603524229, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534520, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558664, Length=242, Percent_Identity=25.6198347107438, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=229, Percent_Identity=27.0742358078603, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85726357, Length=261, Percent_Identity=22.9885057471264, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37109; Mature: 36978

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIELDTPHGRVKALERVSLTINPGELHGLVGESGSGRTLLARAILGVPGHN
CCCCEEECEEEEEECCCHHHHHHHEEEEEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGQNLMDMSAKQRRNLMGSEIAVIFQDPTGSLDPAITVGSQLIEAMPKDK
EEEEECCEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
KISFWKRNKARKAVAQKWLHKVGIKNTEEVMSSYAWELSAGECQKVMIAMAIANQPRLLI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTDSMELSTQAQIFRLLGKLNQLHSVSILLISHELETLSGWCDQLTVLYCGQVMESG
ECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTAEVLEQPFHPYTKALLDNMPDYSGRLTHKSVMQTLPGSAPALQHLPIGCRLGPRCPQA
CCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHH
QKQCVSKPSLCHKKGRYFACHFPYNSEPCNDDSTS
HHHHCCCCHHHHHCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIELDTPHGRVKALERVSLTINPGELHGLVGESGSGRTLLARAILGVPGHN
CCCEEECEEEEEECCCHHHHHHHEEEEEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGQNLMDMSAKQRRNLMGSEIAVIFQDPTGSLDPAITVGSQLIEAMPKDK
EEEEECCEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
KISFWKRNKARKAVAQKWLHKVGIKNTEEVMSSYAWELSAGECQKVMIAMAIANQPRLLI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTDSMELSTQAQIFRLLGKLNQLHSVSILLISHELETLSGWCDQLTVLYCGQVMESG
ECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTAEVLEQPFHPYTKALLDNMPDYSGRLTHKSVMQTLPGSAPALQHLPIGCRLGPRCPQA
CCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHH
QKQCVSKPSLCHKKGRYFACHFPYNSEPCNDDSTS
HHHHCCCCHHHHHCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]