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The map label for this gene is sapC [H]

Identifier: 157962494

GI number: 157962494

Start: 3256425

End: 3257315

Strand: Direct

Name: sapC [H]

Synonym: Spea_2673

Alternate gene names: 157962494

Gene position: 3256425-3257315 (Clockwise)

Preceding gene: 157962493

Following gene: 157962495

Centisome position: 62.93

GC content: 47.47

Gene sequence:

>891_bases
ATGCCGCGAATTAGGATCTACCAAGAAGACCATATTCTTTCTCCAACCCAGAAAGTCTGGCAGGCATTTGCCGATAACCC
ATTTGCACTTGTTGGTCTCTGGGCTGTGTGTTGCATACTTACCTTAGCGGTTTTCGGCCCTTGGATTGCGCCCTTCTCAC
CAGAGCAGCAAGACTCACTCGCGTTACTGTTACCGCCATCTTGGGACGCTAGCGGCACAGTTGAGCACTTTCTCGGGACC
GATGACTTAGGTCGAGATATTTTCAGTCGTCTACTTCACGGCGCTCACCTTACTTTTGGTATGGCGCTGGCAATCGTACT
GGCTTCATTAGTCGTAGGTTTTATTATCGGCTCCATTTCTGGGATGATGAAAGGTCTAAAATCTTCGATATTGAGCCACC
TATTGGATGCGCTCTTATCCATCCCTTCGCTACTATTAGCCATTTTGGTTGTCGCGATAATGGGTCCTGGGCTTGAAAAT
GTATTTTGGGCGGTTGGTATTGCTCTAACGCCGCAGTTTGTTAGGGCTATTCATCAGGCTGTACATGAAGAGTTGCAAAA
AGACTACGTTACGGCAGCGAAGCTAGATGGGGCAAACTCAATTCAAGTTTTTTGGTACGTGATCATGCCTAACGTCTGGG
AAACCGTAATTATTCAAACTACCTTGGCAATTTCTGCCGCAATTTTAGATATTGCCGCGCTGGGATTTTTAAACCTTGGC
GCTCAGGCTCCAAGCCCAGAGTGGGGAGCGATGGTGTCACAAGGGCTTGATAATTTATTAACCGCCCCATGGACGGTAAC
CATCCCTGGTGTTGCCATTTTATGTAGCGTACTGGCTATCAACTTAGTTGGTGACGGTTTGAGATCGGCGTTATCGCCCA
TCAGAAATTAA

Upstream 100 bases:

>100_bases
CAAGGTGGTGTATTGGGCGTTTCACTGACCATTATATTCTTGAGTATCTTAATTGAAGTCATACATAACGCTTATAATCC
GCTAAGCAGGAAAGAGATCT

Downstream 100 bases:

>100_bases
TACTATGCCATTACTCGATATTCGTAATCTCACCATTGAACTCGATACCCCCCATGGACGAGTCAAGGCGCTAGAACGTG
TAAGCTTAACCATTAATCCT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPRIRIYQEDHILSPTQKVWQAFADNPFALVGLWAVCCILTLAVFGPWIAPFSPEQQDSLALLLPPSWDASGTVEHFLGT
DDLGRDIFSRLLHGAHLTFGMALAIVLASLVVGFIIGSISGMMKGLKSSILSHLLDALLSIPSLLLAILVVAIMGPGLEN
VFWAVGIALTPQFVRAIHQAVHEELQKDYVTAAKLDGANSIQVFWYVIMPNVWETVIIQTTLAISAAILDIAALGFLNLG
AQAPSPEWGAMVSQGLDNLLTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPIRN

Sequences:

>Translated_296_residues
MPRIRIYQEDHILSPTQKVWQAFADNPFALVGLWAVCCILTLAVFGPWIAPFSPEQQDSLALLLPPSWDASGTVEHFLGT
DDLGRDIFSRLLHGAHLTFGMALAIVLASLVVGFIIGSISGMMKGLKSSILSHLLDALLSIPSLLLAILVVAIMGPGLEN
VFWAVGIALTPQFVRAIHQAVHEELQKDYVTAAKLDGANSIQVFWYVIMPNVWETVIIQTTLAISAAILDIAALGFLNLG
AQAPSPEWGAMVSQGLDNLLTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPIRN
>Mature_295_residues
PRIRIYQEDHILSPTQKVWQAFADNPFALVGLWAVCCILTLAVFGPWIAPFSPEQQDSLALLLPPSWDASGTVEHFLGTD
DLGRDIFSRLLHGAHLTFGMALAIVLASLVVGFIIGSISGMMKGLKSSILSHLLDALLSIPSLLLAILVVAIMGPGLENV
FWAVGIALTPQFVRAIHQAVHEELQKDYVTAAKLDGANSIQVFWYVIMPNVWETVIIQTTLAISAAILDIAALGFLNLGA
QAPSPEWGAMVSQGLDNLLTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPIRN

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=291, Percent_Identity=49.4845360824742, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI1789964, Length=281, Percent_Identity=46.2633451957295, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1787054, Length=286, Percent_Identity=33.5664335664336, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787760, Length=286, Percent_Identity=36.3636363636364, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=33.739837398374, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=28.5198555956679, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=26.7857142857143, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31731; Mature: 31599

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRIRIYQEDHILSPTQKVWQAFADNPFALVGLWAVCCILTLAVFGPWIAPFSPEQQDSL
CCCCEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
ALLLPPSWDASGTVEHFLGTDDLGRDIFSRLLHGAHLTFGMALAIVLASLVVGFIIGSIS
EEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMKGLKSSILSHLLDALLSIPSLLLAILVVAIMGPGLENVFWAVGIALTPQFVRAIHQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
VHEELQKDYVTAAKLDGANSIQVFWYVIMPNVWETVIIQTTLAISAAILDIAALGFLNLG
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQAPSPEWGAMVSQGLDNLLTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPIRN
CCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRIRIYQEDHILSPTQKVWQAFADNPFALVGLWAVCCILTLAVFGPWIAPFSPEQQDSL
CCCEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
ALLLPPSWDASGTVEHFLGTDDLGRDIFSRLLHGAHLTFGMALAIVLASLVVGFIIGSIS
EEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMKGLKSSILSHLLDALLSIPSLLLAILVVAIMGPGLENVFWAVGIALTPQFVRAIHQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
VHEELQKDYVTAAKLDGANSIQVFWYVIMPNVWETVIIQTTLAISAAILDIAALGFLNLG
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQAPSPEWGAMVSQGLDNLLTAPWTVTIPGVAILCSVLAINLVGDGLRSALSPIRN
CCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]