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The map label for this gene is dppB [H]

Identifier: 157962493

GI number: 157962493

Start: 3255407

End: 3256438

Strand: Direct

Name: dppB [H]

Synonym: Spea_2672

Alternate gene names: 157962493

Gene position: 3255407-3256438 (Clockwise)

Preceding gene: 157962492

Following gene: 157962494

Centisome position: 62.91

GC content: 43.8

Gene sequence:

>1032_bases
ATGGGCCGCTATCTCCTACGCAGATTAAACCTGTTTATAGCAACCAGTTTTGTCCTAATTGCTGTCTTGTTCATAACAAC
GGGTTATTTTCCAACCAATAAAGCCGTTGCATTAACCGGGATCACTGCTCCAACACCAGAGCAACTACAAAATATCGAAC
AGACTTATCAGCTAAATGAGAGTCAACTAGAACAATTTTTTGCCTATACCAAAACTCGCTTAAGTGGCGACTTAGGCCTA
TCGGTCACTTCGCAGCGCCCCGTTATTGAAGAGCTGACTCAGGCACTTCCCGCGTCATTTGAGCTTGCTATCGTATCCGG
CTTAATTGCAGTGCTACTTGGTGTACCACTTGGAGTGCTTGCTTCACTAAGTAAGAACAAGGTCACCCAGCACAGTATTA
TGGCAATTACTTTAACTGGTTACTCCATTCCTGTTTTTTGGCTTGGACTAACACTGTCGTTATGGTTTGGGGTTAAACTT
GGTTGGCTTCCGGTTTCTGGACGGATCAATCTGTTATATGAGATAGAGCCAGTGACAGGCTTTATGCTAATCGATACCTT
ACTCTGGGATTCTGTCTATCGTTTTTCCGCTTTTAAGGATGCACTGTTCCATATTATCTTACCGTCGATAACCTTAGCGG
TACTCCCGTTTACTGTGGTCGTCCGTATAACTCGTGCTGCCATGCTCAACATCATGGAGTTACCCTATATTAAAGCCGCT
GAAGCCAGAGGCTTACATACCAGCACAATTGTGCTGCGTCATGCACTACCAAATGCATTGATCCCTGTATTAAAAAATAT
GGGCCTAATGCTAGGTACCTTTGCCACTTATTCCATGATTGTCGAGGTTATCTTCTCATGGCCCGGCGTGGGCAGTTGGT
TGGTATCTGGAATTTATCAGCGAGATTACACCGTTATTCAAGGTGGTGTATTGGGCGTTTCACTGACCATTATATTCTTG
AGTATCTTAATTGAAGTCATACATAACGCTTATAATCCGCTAAGCAGGAAAGAGATCTATGCCGCGAATTAG

Upstream 100 bases:

>100_bases
TGACCTTTAAGAGCAAAGATATTAAACAAACTCAGCTTACTCCTTTTGGTGGGATCTCATTTGAACGAGCCAAGAAAATA
ACATCAGAGGAGGAGCTATA

Downstream 100 bases:

>100_bases
GATCTACCAAGAAGACCATATTCTTTCTCCAACCCAGAAAGTCTGGCAGGCATTTGCCGATAACCCATTTGCACTTGTTG
GTCTCTGGGCTGTGTGTTGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGRYLLRRLNLFIATSFVLIAVLFITTGYFPTNKAVALTGITAPTPEQLQNIEQTYQLNESQLEQFFAYTKTRLSGDLGL
SVTSQRPVIEELTQALPASFELAIVSGLIAVLLGVPLGVLASLSKNKVTQHSIMAITLTGYSIPVFWLGLTLSLWFGVKL
GWLPVSGRINLLYEIEPVTGFMLIDTLLWDSVYRFSAFKDALFHIILPSITLAVLPFTVVVRITRAAMLNIMELPYIKAA
EARGLHTSTIVLRHALPNALIPVLKNMGLMLGTFATYSMIVEVIFSWPGVGSWLVSGIYQRDYTVIQGGVLGVSLTIIFL
SILIEVIHNAYNPLSRKEIYAAN

Sequences:

>Translated_343_residues
MGRYLLRRLNLFIATSFVLIAVLFITTGYFPTNKAVALTGITAPTPEQLQNIEQTYQLNESQLEQFFAYTKTRLSGDLGL
SVTSQRPVIEELTQALPASFELAIVSGLIAVLLGVPLGVLASLSKNKVTQHSIMAITLTGYSIPVFWLGLTLSLWFGVKL
GWLPVSGRINLLYEIEPVTGFMLIDTLLWDSVYRFSAFKDALFHIILPSITLAVLPFTVVVRITRAAMLNIMELPYIKAA
EARGLHTSTIVLRHALPNALIPVLKNMGLMLGTFATYSMIVEVIFSWPGVGSWLVSGIYQRDYTVIQGGVLGVSLTIIFL
SILIEVIHNAYNPLSRKEIYAAN
>Mature_342_residues
GRYLLRRLNLFIATSFVLIAVLFITTGYFPTNKAVALTGITAPTPEQLQNIEQTYQLNESQLEQFFAYTKTRLSGDLGLS
VTSQRPVIEELTQALPASFELAIVSGLIAVLLGVPLGVLASLSKNKVTQHSIMAITLTGYSIPVFWLGLTLSLWFGVKLG
WLPVSGRINLLYEIEPVTGFMLIDTLLWDSVYRFSAFKDALFHIILPSITLAVLPFTVVVRITRAAMLNIMELPYIKAAE
ARGLHTSTIVLRHALPNALIPVLKNMGLMLGTFATYSMIVEVIFSWPGVGSWLVSGIYQRDYTVIQGGVLGVSLTIIFLS
ILIEVIHNAYNPLSRKEIYAAN

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=36.3636363636364, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=44.1509433962264, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=31.9526627218935, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1787761, Length=288, Percent_Identity=38.8888888888889, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789888, Length=342, Percent_Identity=30.4093567251462, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=32.2485207100592, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788504, Length=374, Percent_Identity=24.0641711229947, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37867; Mature: 37736

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRYLLRRLNLFIATSFVLIAVLFITTGYFPTNKAVALTGITAPTPEQLQNIEQTYQLNE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
SQLEQFFAYTKTRLSGDLGLSVTSQRPVIEELTQALPASFELAIVSGLIAVLLGVPLGVL
HHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASLSKNKVTQHSIMAITLTGYSIPVFWLGLTLSLWFGVKLGWLPVSGRINLLYEIEPVTG
HHHHHCCCCHHEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCHH
FMLIDTLLWDSVYRFSAFKDALFHIILPSITLAVLPFTVVVRITRAAMLNIMELPYIKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHH
EARGLHTSTIVLRHALPNALIPVLKNMGLMLGTFATYSMIVEVIFSWPGVGSWLVSGIYQ
HCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGVLGVSLTIIFLSILIEVIHNAYNPLSRKEIYAAN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GRYLLRRLNLFIATSFVLIAVLFITTGYFPTNKAVALTGITAPTPEQLQNIEQTYQLNE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
SQLEQFFAYTKTRLSGDLGLSVTSQRPVIEELTQALPASFELAIVSGLIAVLLGVPLGVL
HHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASLSKNKVTQHSIMAITLTGYSIPVFWLGLTLSLWFGVKLGWLPVSGRINLLYEIEPVTG
HHHHHCCCCHHEEEEEEEECCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCHH
FMLIDTLLWDSVYRFSAFKDALFHIILPSITLAVLPFTVVVRITRAAMLNIMELPYIKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHH
EARGLHTSTIVLRHALPNALIPVLKNMGLMLGTFATYSMIVEVIFSWPGVGSWLVSGIYQ
HCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGVLGVSLTIIFLSILIEVIHNAYNPLSRKEIYAAN
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]