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The map label for this gene is 157962481

Identifier: 157962481

GI number: 157962481

Start: 3241610

End: 3242524

Strand: Direct

Name: 157962481

Synonym: Spea_2660

Alternate gene names: NA

Gene position: 3241610-3242524 (Clockwise)

Preceding gene: 157962480

Following gene: 157962482

Centisome position: 62.64

GC content: 44.81

Gene sequence:

>915_bases
ATGGTCCCTCTAATCTATGACGCCAGCTACTCCAAGCTGGCGTTACCTCCTCTTCATCGCTTTCCAATTAGTAAATACCG
CGCCTTATATGAATACCTGCTCGAGCAAGGTATTGCTGAACAACCGCAATTTATCGCCCCCACAAAAGCGAGCATCGAAT
ATCTCACAGCGTTGCACGACCAAAGCTATGTGAAAGACTTTATTTCAGGTGAACTAGACAGCAAATTAATGCGCCGAATT
GGTTTCCCGTGGAGCAAAGCGTTAGTCGAACGAACCTTATATTCGGTAGCAGGCACCGCACTGACCTGTGAGCAAGCGAT
AACCCATGGCTGCGCCATTCATTTAAGCGGCGGTTACCATCATGCCCACCAGCAGTTTGGCAGTGGCTACTGTATTTTTA
ACGATCTCGTACTCGCGGCGGTGAATAGCCAACAAATTGATGATATTGAAACTGTGCTCATTTTCGACTGCGATGTTCAT
CAAGGTGACGGGACAGCAACGATTGCACAATCATTAAATCATGTCATCACTTGCTCTATTCATTGCCATCAAAACTTCCC
AGCACGAAAACAGCAATCAGATTACGATATCGAGCTTGATAAGGGCACGTCAGATATTGAGTACGTAGAGACTGTAGAGC
AGACACTTGCCTACCTTATTCGACTGCATAAGCCAGACCTGATTATTTACGATGCTGGTGTGGATATTCATAGTGATGAC
AACTTGGGGTATTTAAATATCAGCACAGATGGGATCTACGCCAGAGACTTAGAAGTCATCCATCAAGCTAAAACAGCACA
AATACCCATTGCGTGTGTTATAGGAGGGGGATACAGTAGAGATTCGACACAGCTAAGTGTTCGACATAGCCAAGTGTTTA
TTGCGGCAAATAATTTTTGGCAGTCAACAAGTTAA

Upstream 100 bases:

>100_bases
ATATTGGTGGTTGCAAGCCGACGAGCAAACGCGTAAAGAATTCATGAGCTGGGCAATTAAGCAGCTTTAAGTTAGCAGCA
GTTCTTACTCAAGATTGTGT

Downstream 100 bases:

>100_bases
ACGTCATGTCGTGGCTTTATAGCCACCAAACAAGGAGCGTTATATGCAATTAGAGATAAGAAACTACTACGAAGTGCTAC
TACTCGAGCAACTTTCTGAT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MVPLIYDASYSKLALPPLHRFPISKYRALYEYLLEQGIAEQPQFIAPTKASIEYLTALHDQSYVKDFISGELDSKLMRRI
GFPWSKALVERTLYSVAGTALTCEQAITHGCAIHLSGGYHHAHQQFGSGYCIFNDLVLAAVNSQQIDDIETVLIFDCDVH
QGDGTATIAQSLNHVITCSIHCHQNFPARKQQSDYDIELDKGTSDIEYVETVEQTLAYLIRLHKPDLIIYDAGVDIHSDD
NLGYLNISTDGIYARDLEVIHQAKTAQIPIACVIGGGYSRDSTQLSVRHSQVFIAANNFWQSTS

Sequences:

>Translated_304_residues
MVPLIYDASYSKLALPPLHRFPISKYRALYEYLLEQGIAEQPQFIAPTKASIEYLTALHDQSYVKDFISGELDSKLMRRI
GFPWSKALVERTLYSVAGTALTCEQAITHGCAIHLSGGYHHAHQQFGSGYCIFNDLVLAAVNSQQIDDIETVLIFDCDVH
QGDGTATIAQSLNHVITCSIHCHQNFPARKQQSDYDIELDKGTSDIEYVETVEQTLAYLIRLHKPDLIIYDAGVDIHSDD
NLGYLNISTDGIYARDLEVIHQAKTAQIPIACVIGGGYSRDSTQLSVRHSQVFIAANNFWQSTS
>Mature_304_residues
MVPLIYDASYSKLALPPLHRFPISKYRALYEYLLEQGIAEQPQFIAPTKASIEYLTALHDQSYVKDFISGELDSKLMRRI
GFPWSKALVERTLYSVAGTALTCEQAITHGCAIHLSGGYHHAHQQFGSGYCIFNDLVLAAVNSQQIDDIETVLIFDCDVH
QGDGTATIAQSLNHVITCSIHCHQNFPARKQQSDYDIELDKGTSDIEYVETVEQTLAYLIRLHKPDLIIYDAGVDIHSDD
NLGYLNISTDGIYARDLEVIHQAKTAQIPIACVIGGGYSRDSTQLSVRHSQVFIAANNFWQSTS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=277, Percent_Identity=29.2418772563177, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI217272877, Length=297, Percent_Identity=27.9461279461279, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI13128860, Length=283, Percent_Identity=26.1484098939929, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI293336691, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI8923769, Length=285, Percent_Identity=25.2631578947368, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI13128862, Length=180, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI262073092, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=301, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17508561, Length=300, Percent_Identity=24.3333333333333, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=277, Percent_Identity=25.2707581227437, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193206283, Length=179, Percent_Identity=30.7262569832402, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=179, Percent_Identity=30.7262569832402, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534739, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537347, Length=176, Percent_Identity=28.9772727272727, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323999, Length=301, Percent_Identity=24.9169435215947, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=212, Percent_Identity=29.7169811320755, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325325, Length=178, Percent_Identity=27.5280898876405, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24649807, Length=295, Percent_Identity=25.4237288135593, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24657891, Length=284, Percent_Identity=26.056338028169, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644244, Length=197, Percent_Identity=27.9187817258883, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360899, Length=267, Percent_Identity=26.2172284644195, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642144, Length=267, Percent_Identity=26.2172284644195, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642142, Length=267, Percent_Identity=26.2172284644195, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642146, Length=267, Percent_Identity=26.2172284644195, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33899; Mature: 33899

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPLIYDASYSKLALPPLHRFPISKYRALYEYLLEQGIAEQPQFIAPTKASIEYLTALHD
CCCEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCC
QSYVKDFISGELDSKLMRRIGFPWSKALVERTLYSVAGTALTCEQAITHGCAIHLSGGYH
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCH
HAHQQFGSGYCIFNDLVLAAVNSQQIDDIETVLIFDCDVHQGDGTATIAQSLNHVITCSI
HHHHHHCCCEEEEHHHHHEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHCCCEEEEEEE
HCHQNFPARKQQSDYDIELDKGTSDIEYVETVEQTLAYLIRLHKPDLIIYDAGVDIHSDD
EECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCC
NLGYLNISTDGIYARDLEVIHQAKTAQIPIACVIGGGYSRDSTQLSVRHSQVFIAANNFW
CEEEEEEECCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCC
QSTS
CCCC
>Mature Secondary Structure
MVPLIYDASYSKLALPPLHRFPISKYRALYEYLLEQGIAEQPQFIAPTKASIEYLTALHD
CCCEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCC
QSYVKDFISGELDSKLMRRIGFPWSKALVERTLYSVAGTALTCEQAITHGCAIHLSGGYH
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCH
HAHQQFGSGYCIFNDLVLAAVNSQQIDDIETVLIFDCDVHQGDGTATIAQSLNHVITCSI
HHHHHHCCCEEEEHHHHHEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHCCCEEEEEEE
HCHQNFPARKQQSDYDIELDKGTSDIEYVETVEQTLAYLIRLHKPDLIIYDAGVDIHSDD
EECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCC
NLGYLNISTDGIYARDLEVIHQAKTAQIPIACVIGGGYSRDSTQLSVRHSQVFIAANNFW
CEEEEEEECCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCC
QSTS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]