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The map label for this gene is ykoW [H]

Identifier: 157962414

GI number: 157962414

Start: 3158031

End: 3162341

Strand: Direct

Name: ykoW [H]

Synonym: Spea_2593

Alternate gene names: 157962414

Gene position: 3158031-3162341 (Clockwise)

Preceding gene: 157962413

Following gene: 157962415

Centisome position: 61.03

GC content: 37.51

Gene sequence:

>4311_bases
ATGTTGGCTAATAATCAAACAGAAAATATGCCTAGAATTCTTATAAAAATCGCGACTTTTCTACTCTTTTGCATTTCTAT
GGCAAATTCTGCCTATGCATTAACCTTAAACTCTACTTCTTTAGGCGTTCAAGATGGTTTATCACAAAGCAATGTGACCT
CCATTGTCGAAGATGCCGATGGTTATATCTGGATAGGAACAGTCAATGGCCTTAATCGATATGACGGTAAAGAGTTTCGC
CATTACTTCCCATCCAAAGAGAATGAACTCCCAAGTGCATTCATTCGTAGTCTATTTATCAGCGATACGGGTGTAATGTA
CATAGGTACTGATAAAGGTCTAGCTGTTTATGATTCATTAACCGATAGAGTGATCTCAATAAAGTCAGGCGACTTTCTTA
AAGAACAAGCTATTTGGTCAATATCTGATAATGGAAATGAAATTATTATTGGGGCAGAGAATGCAGTTTATATAACACAA
GAAAATTCAAAAGAAGCTGTTCTTGAATTATTAAACTCCTACAGTGGCGATTATAATGGAGTAAAGCAAGCAATTCATTT
CAAGAATGAAATATACATAAGGAATTATATAGGCGAAGTTAAATCAATACAAAACACCCATGAACTTTACTTCCAAAAAG
CTACAGCAATAAAAGAAATCAACAATAAACTAGTCGTGTTCACAACCGACGGTATATATGAGATGGCAAACGCGTCATTC
TCAAAAAAAAATAACGATTCATTTATAAGCGTTTCCTCTGGAGATGGGCATTTCGCATTAAAAGAAAGTGCCATCTATGA
TATATCGAAACTTACAAGCCCTTTATTAATCGGAACCCCATCTCTATCAGAAAGAGAACTAAACCTGTCAAGGATAAATA
TTTTTAGAGGGTTAAATAAAACCTTCATAGCACATCAAAATGAAGGGGTAATTATAATAGATGATAATTATAATCTCATC
CAAAGTATTACTAACAACATTGGCAACGTATGGTCTATATCTGAAGACGACGAAAATAAAATTTTAGTAACTACTGAGGA
TAGTAAACTAAAACTGTATAACTTAGAATTTGAACTAATTAAAGAATATGAAACTGGACTATATGGAAACAAATCAGCTT
TAACGGTTGATAACAATATATACATTGCCAGCGATCTAGGCCTTTTTTCTATCAATAAACAGACTGAAGTCTTATCCAGT
GTGAACCAAGGTTCATACTTCCTGTTAGAGAAATTAAACGATGGTAAGACCATAGTTGCTGGTTCATCAAATGGATCCAT
ATTAAAATATAACACTCTAGACAAATCATCTAAGAACATTAGAATTGACAGAGTAAACCCTATATTTGACATTCAAGAAC
TAAATAACTCTTTGTATGTTGGTACGCAAAGCGGCCTATATAAAGTTGAAAACAACAAAACAAAAATAATATATGACGAA
AACTTTGTAACAAGCATTACAAAATCTGGTAGTTCACTATACTTCGGAACAAGCACTGGGATAAAAAAGTACTCAACAAC
GAGAAACAGCATTGAAGATGTTTACTCCAACAAAAAACCGATATTTTCTTTAGCCATAAATAATCAACAGTTATACGCAT
CATCGATAAATGAAGTGATCATTCATAACTTCAAAAACACTTCAACTTCAATACTAACTAATGAGTTAGGAGCGCAAGAA
GAATACAATTTACAATCTATCCTAGACAATGATAGTGAAGTTTATATTGGTGGTATTTCCGGAGTCAGTAGAATAATCAC
TAAAGAATTGAATTCTTTTTTAGAACGCAACACTCCGCCTATAACCGAACTAACAGAACTTTCGATCTTTAATATTATCG
AAGAACCAAATGGCTCCGTACTAAAAAATCAATTATCTCAGACAGATAAAATAAAGTTGAAATATTCTGACTACCCCTTC
ACTCTATCTTTTAGCAGCCCAGGCAGCTCTTTTAAACATATTAACTATGTATATCAAATGCAGGGACTTTCGGAATCTCA
GATCCAATCAAAAGGCACAAATTCGGCAACCTATACCAATTTGTCTCCAGGGGATTATATTTTTTCCATCTATGCAATAG
ACCCTGTTACGGGTAAGAAAGGACAAATTCGTGAGTTAAATATTGAGATCACACCACCTTGGTGGTTATCAATCACGGCG
AAGTTTATCTATCTACTCTGTTTCATATTCATCTCTATCTTAATTATCAAAACCATACTACGTCGGCGTGAAATTCAAAG
ACAGATAGCCAAGAGTGAGGAGCGCCTTAAGCTTTCTCTTTGGGGAAGTGGCGATGAAATGTGGGACTGGGACATTGAAA
CAGGCCAAATTTACCGCTCAAATATCTGGGGCTCCCTAGAGTTCCCTCAAGATGGACAGCGTTCAGGTAATAATGGGGAA
GAGAGTAACATCCACCCAATGGATCAGGAGCGTGTCCGCGAAGCATTAAATAAACATTTTTACGGTGAAACCGATCACTT
TGAAGCGGCCTATCGAGTCAAAGGCAAATCAAACGACTGGGTTTGGATCTTAGATAGAGCGAAAATTGTTGAACGTGATG
AAAACGATAATGCGCTCAGAATGACAGGAACCATCAAAAACATCAGCAACTTTAAGCAAGCCGAAGAACAATTAAGATTG
TTTGAACGGGCCATTCAGAATATTTCTGAAGGTATGTTTATTCTCGATAGAAACTTTAAGTTTGTAGAAGTGAATGAAGC
ATGCTGCGACTTATCTATGATGAGTAAGAATGAGCTCATTGGCACCCTATTTAATTTTGATCTCTATCCAGATAGCTATT
CAGAGCAGATCCGTTCAATACTTAAGCAACAAGGCCGTTGGAACAATGAAGTCGAATCAATAAGAGGCAACGGCAGCAGC
TTTTTAATGGAGCTCTCCGTCGATGCTATTTATGATGAGCAAGGCGAACTATCACATTTTGTAGGTGTATTCTCCGATGT
CAGTCGCCGTAAACAACAAGAAGAAGAGCTTAGAAAACTCACAAACAACGATCTGCTAACTAACTTACCTAACCGTTCTA
ATTTGATGGTAACCCTTGGCAACCTAGTCAAGAGAGACTCTCACCATACTCTGATGGTTTTAGATTTAGATAATTTTAAG
AAAATTAATGATTCATTAGGGCATCAAGCCGGAGATGAACTTTTAGTACAAGTGTCAGAACGTATTCAAGTCGCCGTACC
TAGTCATACCAGTATCTATCGCTTAGGTGGAGATGAGTTTGCAATATTAGTTGATAAAAATCCTGATATCGGGACTAGCG
CCATAATTGCCAAAAACGTTATTCACGCCTTCGAAGCCTCTTTTGAACTAAGCAGTGAAAAAGTCGTCGTTGGTTTAAGT
ATTGGTATTGTGTTGTATCCAGAAGATGATCAAAACGAGCAGGCGCTCCTAAGAAAGGCAGATATCGCTATGTATCATGC
TAAATCAGCAGGTGGTAACCGTTATCAATTCTACTCTGAATCCTTGAACAAAAATGCCATTCGCCAGTTAGAAGTTGAAA
ACCTGATTAGAGATGGCCTTAAAGACGATCTATTTGAAGTCTATTATCAGCCTAAAGTCGATTTAAAAACTGGCCATATG
GCGGGAATGGAAGCCTTAGTGCGCTTAAATCACCCAGAGCTAGGTTTAATCGCACCTAATGAATTTATCCCATTAGCAGA
AGAGAATGGCTTGATTGTCGAAATTGGCGATGTAGTACTCAAGAAAGCCTGCTTCGCGGCGCAAAAGTGGCGCTCACAAG
GCTTGTTCAACGGACGAGTCGCTGTCAATTTATCGTCGAAACAGTTCGCATTACCTGATTTACAGCAGCGAGTCGAGTCA
ATTTTACGTCTAACTCAATTACCCGCCGCTAATTTAGAGCTCGAAATAACCGAAGGTACGGTTATTAAAGAGCCTGAAAA
AGCAATCAAAGTGATGCAGCAATTATCTAAAATGGGCGTTAGTTTAGCCCTCGACGATTTTGGTACCGGTTACTCATCAC
TTTCTTATTTAAAGCGCTTTCCTATCCACACTTTAAAAATTGACAAGGCTTTTGTTGATGATATTGACAAGTCTGATCGC
GATCTAAAAATGGTCGACTCTATTATCACTATTGCCCACAATATGGGGCTCTCAGTGGTTGGTGAAGGTGTTGAAGATGC
CTCTCAGCTCAGTATATTGCGCGCCTTAAAATGTGAAGAGATCCAAGGCTATATCTTCAGCAAGCCTGTGACTGAATCCA
AATTTACCCTGCTACTTCAGCAAGACTCGAATAACCAACCAATGACAGCACTCCCCGCAAAAAGAGGTTAA

Upstream 100 bases:

>100_bases
CAGAAAGGATAAGAATGATTATCTGCTACAATTACCTCTATAATTTTTGACAATACCCTCGCTTTCTGAAAAGGTGGTGA
TAACAAGTAGTTGCCTTTCA

Downstream 100 bases:

>100_bases
AAGACGCAACGCAGGAAACATTGGCACAACAACTGCAACAACCTTCTCATAAGTCAAAAATATTATTTTATATTTAAAAC
TCTACGAGAAGGTACAAAAT

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1436; Mature: 1436

Protein sequence:

>1436_residues
MLANNQTENMPRILIKIATFLLFCISMANSAYALTLNSTSLGVQDGLSQSNVTSIVEDADGYIWIGTVNGLNRYDGKEFR
HYFPSKENELPSAFIRSLFISDTGVMYIGTDKGLAVYDSLTDRVISIKSGDFLKEQAIWSISDNGNEIIIGAENAVYITQ
ENSKEAVLELLNSYSGDYNGVKQAIHFKNEIYIRNYIGEVKSIQNTHELYFQKATAIKEINNKLVVFTTDGIYEMANASF
SKKNNDSFISVSSGDGHFALKESAIYDISKLTSPLLIGTPSLSERELNLSRINIFRGLNKTFIAHQNEGVIIIDDNYNLI
QSITNNIGNVWSISEDDENKILVTTEDSKLKLYNLEFELIKEYETGLYGNKSALTVDNNIYIASDLGLFSINKQTEVLSS
VNQGSYFLLEKLNDGKTIVAGSSNGSILKYNTLDKSSKNIRIDRVNPIFDIQELNNSLYVGTQSGLYKVENNKTKIIYDE
NFVTSITKSGSSLYFGTSTGIKKYSTTRNSIEDVYSNKKPIFSLAINNQQLYASSINEVIIHNFKNTSTSILTNELGAQE
EYNLQSILDNDSEVYIGGISGVSRIITKELNSFLERNTPPITELTELSIFNIIEEPNGSVLKNQLSQTDKIKLKYSDYPF
TLSFSSPGSSFKHINYVYQMQGLSESQIQSKGTNSATYTNLSPGDYIFSIYAIDPVTGKKGQIRELNIEITPPWWLSITA
KFIYLLCFIFISILIIKTILRRREIQRQIAKSEERLKLSLWGSGDEMWDWDIETGQIYRSNIWGSLEFPQDGQRSGNNGE
ESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKSNDWVWILDRAKIVERDENDNALRMTGTIKNISNFKQAEEQLRL
FERAIQNISEGMFILDRNFKFVEVNEACCDLSMMSKNELIGTLFNFDLYPDSYSEQIRSILKQQGRWNNEVESIRGNGSS
FLMELSVDAIYDEQGELSHFVGVFSDVSRRKQQEEELRKLTNNDLLTNLPNRSNLMVTLGNLVKRDSHHTLMVLDLDNFK
KINDSLGHQAGDELLVQVSERIQVAVPSHTSIYRLGGDEFAILVDKNPDIGTSAIIAKNVIHAFEASFELSSEKVVVGLS
IGIVLYPEDDQNEQALLRKADIAMYHAKSAGGNRYQFYSESLNKNAIRQLEVENLIRDGLKDDLFEVYYQPKVDLKTGHM
AGMEALVRLNHPELGLIAPNEFIPLAEENGLIVEIGDVVLKKACFAAQKWRSQGLFNGRVAVNLSSKQFALPDLQQRVES
ILRLTQLPAANLELEITEGTVIKEPEKAIKVMQQLSKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDR
DLKMVDSIITIAHNMGLSVVGEGVEDASQLSILRALKCEEIQGYIFSKPVTESKFTLLLQQDSNNQPMTALPAKRG

Sequences:

>Translated_1436_residues
MLANNQTENMPRILIKIATFLLFCISMANSAYALTLNSTSLGVQDGLSQSNVTSIVEDADGYIWIGTVNGLNRYDGKEFR
HYFPSKENELPSAFIRSLFISDTGVMYIGTDKGLAVYDSLTDRVISIKSGDFLKEQAIWSISDNGNEIIIGAENAVYITQ
ENSKEAVLELLNSYSGDYNGVKQAIHFKNEIYIRNYIGEVKSIQNTHELYFQKATAIKEINNKLVVFTTDGIYEMANASF
SKKNNDSFISVSSGDGHFALKESAIYDISKLTSPLLIGTPSLSERELNLSRINIFRGLNKTFIAHQNEGVIIIDDNYNLI
QSITNNIGNVWSISEDDENKILVTTEDSKLKLYNLEFELIKEYETGLYGNKSALTVDNNIYIASDLGLFSINKQTEVLSS
VNQGSYFLLEKLNDGKTIVAGSSNGSILKYNTLDKSSKNIRIDRVNPIFDIQELNNSLYVGTQSGLYKVENNKTKIIYDE
NFVTSITKSGSSLYFGTSTGIKKYSTTRNSIEDVYSNKKPIFSLAINNQQLYASSINEVIIHNFKNTSTSILTNELGAQE
EYNLQSILDNDSEVYIGGISGVSRIITKELNSFLERNTPPITELTELSIFNIIEEPNGSVLKNQLSQTDKIKLKYSDYPF
TLSFSSPGSSFKHINYVYQMQGLSESQIQSKGTNSATYTNLSPGDYIFSIYAIDPVTGKKGQIRELNIEITPPWWLSITA
KFIYLLCFIFISILIIKTILRRREIQRQIAKSEERLKLSLWGSGDEMWDWDIETGQIYRSNIWGSLEFPQDGQRSGNNGE
ESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKSNDWVWILDRAKIVERDENDNALRMTGTIKNISNFKQAEEQLRL
FERAIQNISEGMFILDRNFKFVEVNEACCDLSMMSKNELIGTLFNFDLYPDSYSEQIRSILKQQGRWNNEVESIRGNGSS
FLMELSVDAIYDEQGELSHFVGVFSDVSRRKQQEEELRKLTNNDLLTNLPNRSNLMVTLGNLVKRDSHHTLMVLDLDNFK
KINDSLGHQAGDELLVQVSERIQVAVPSHTSIYRLGGDEFAILVDKNPDIGTSAIIAKNVIHAFEASFELSSEKVVVGLS
IGIVLYPEDDQNEQALLRKADIAMYHAKSAGGNRYQFYSESLNKNAIRQLEVENLIRDGLKDDLFEVYYQPKVDLKTGHM
AGMEALVRLNHPELGLIAPNEFIPLAEENGLIVEIGDVVLKKACFAAQKWRSQGLFNGRVAVNLSSKQFALPDLQQRVES
ILRLTQLPAANLELEITEGTVIKEPEKAIKVMQQLSKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDR
DLKMVDSIITIAHNMGLSVVGEGVEDASQLSILRALKCEEIQGYIFSKPVTESKFTLLLQQDSNNQPMTALPAKRG
>Mature_1436_residues
MLANNQTENMPRILIKIATFLLFCISMANSAYALTLNSTSLGVQDGLSQSNVTSIVEDADGYIWIGTVNGLNRYDGKEFR
HYFPSKENELPSAFIRSLFISDTGVMYIGTDKGLAVYDSLTDRVISIKSGDFLKEQAIWSISDNGNEIIIGAENAVYITQ
ENSKEAVLELLNSYSGDYNGVKQAIHFKNEIYIRNYIGEVKSIQNTHELYFQKATAIKEINNKLVVFTTDGIYEMANASF
SKKNNDSFISVSSGDGHFALKESAIYDISKLTSPLLIGTPSLSERELNLSRINIFRGLNKTFIAHQNEGVIIIDDNYNLI
QSITNNIGNVWSISEDDENKILVTTEDSKLKLYNLEFELIKEYETGLYGNKSALTVDNNIYIASDLGLFSINKQTEVLSS
VNQGSYFLLEKLNDGKTIVAGSSNGSILKYNTLDKSSKNIRIDRVNPIFDIQELNNSLYVGTQSGLYKVENNKTKIIYDE
NFVTSITKSGSSLYFGTSTGIKKYSTTRNSIEDVYSNKKPIFSLAINNQQLYASSINEVIIHNFKNTSTSILTNELGAQE
EYNLQSILDNDSEVYIGGISGVSRIITKELNSFLERNTPPITELTELSIFNIIEEPNGSVLKNQLSQTDKIKLKYSDYPF
TLSFSSPGSSFKHINYVYQMQGLSESQIQSKGTNSATYTNLSPGDYIFSIYAIDPVTGKKGQIRELNIEITPPWWLSITA
KFIYLLCFIFISILIIKTILRRREIQRQIAKSEERLKLSLWGSGDEMWDWDIETGQIYRSNIWGSLEFPQDGQRSGNNGE
ESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKSNDWVWILDRAKIVERDENDNALRMTGTIKNISNFKQAEEQLRL
FERAIQNISEGMFILDRNFKFVEVNEACCDLSMMSKNELIGTLFNFDLYPDSYSEQIRSILKQQGRWNNEVESIRGNGSS
FLMELSVDAIYDEQGELSHFVGVFSDVSRRKQQEEELRKLTNNDLLTNLPNRSNLMVTLGNLVKRDSHHTLMVLDLDNFK
KINDSLGHQAGDELLVQVSERIQVAVPSHTSIYRLGGDEFAILVDKNPDIGTSAIIAKNVIHAFEASFELSSEKVVVGLS
IGIVLYPEDDQNEQALLRKADIAMYHAKSAGGNRYQFYSESLNKNAIRQLEVENLIRDGLKDDLFEVYYQPKVDLKTGHM
AGMEALVRLNHPELGLIAPNEFIPLAEENGLIVEIGDVVLKKACFAAQKWRSQGLFNGRVAVNLSSKQFALPDLQQRVES
ILRLTQLPAANLELEITEGTVIKEPEKAIKVMQQLSKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDR
DLKMVDSIITIAHNMGLSVVGEGVEDASQLSILRALKCEEIQGYIFSKPVTESKFTLLLQQDSNNQPMTALPAKRG

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=36.4896073903002, Blast_Score=285, Evalue=1e-77,
Organism=Escherichia coli, GI87081921, Length=444, Percent_Identity=32.2072072072072, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=27.1186440677966, Blast_Score=176, Evalue=9e-45,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=31.4606741573034, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=31.2252964426877, Blast_Score=128, Evalue=3e-30,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=32.2175732217573, Blast_Score=126, Evalue=8e-30,
Organism=Escherichia coli, GI1790496, Length=262, Percent_Identity=30.9160305343511, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1787055, Length=385, Percent_Identity=25.1948051948052, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=29.6747967479675, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=31.25, Blast_Score=117, Evalue=7e-27,
Organism=Escherichia coli, GI87082096, Length=429, Percent_Identity=24.9417249417249, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=29.7520661157025, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788381, Length=321, Percent_Identity=28.3489096573209, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=29.7752808988764, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI87081977, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=185, Percent_Identity=32.972972972973, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=34.375, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=29.0123456790123, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=32.3170731707317, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1789650, Length=428, Percent_Identity=20.7943925233645, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=28.9940828402367, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 161624; Mature: 161624

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANNQTENMPRILIKIATFLLFCISMANSAYALTLNSTSLGVQDGLSQSNVTSIVEDAD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCHHHHHHHCCC
GYIWIGTVNGLNRYDGKEFRHYFPSKENELPSAFIRSLFISDTGVMYIGTDKGLAVYDSL
CEEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
TDRVISIKSGDFLKEQAIWSISDNGNEIIIGAENAVYITQENSKEAVLELLNSYSGDYNG
CCCEEEECCCCCCHHCEEEEECCCCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCHHH
VKQAIHFKNEIYIRNYIGEVKSIQNTHELYFQKATAIKEINNKLVVFTTDGIYEMANASF
HHHHHHHCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCC
SKKNNDSFISVSSGDGHFALKESAIYDISKLTSPLLIGTPSLSERELNLSRINIFRGLNK
CCCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCC
TFIAHQNEGVIIIDDNYNLIQSITNNIGNVWSISEDDENKILVTTEDSKLKLYNLEFELI
EEEEECCCCEEEECCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCEEEEEECHHHHH
KEYETGLYGNKSALTVDNNIYIASDLGLFSINKQTEVLSSVNQGSYFLLEKLNDGKTIVA
HHHHCCCCCCCCEEEECCCEEEEECCCEEEECCHHHHHHHCCCCCEEEEEECCCCCEEEE
GSSNGSILKYNTLDKSSKNIRIDRVNPIFDIQELNNSLYVGTQSGLYKVENNKTKIIYDE
ECCCCCEEEEECCCCCCCCEEEECCCCEEEHHHCCCEEEEECCCCEEEEECCCEEEEECC
NFVTSITKSGSSLYFGTSTGIKKYSTTRNSIEDVYSNKKPIFSLAINNQQLYASSINEVI
CCEEHHHCCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHH
IHNFKNTSTSILTNELGAQEEYNLQSILDNDSEVYIGGISGVSRIITKELNSFLERNTPP
HCCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
ITELTELSIFNIIEEPNGSVLKNQLSQTDKIKLKYSDYPFTLSFSSPGSSFKHINYVYQM
CHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCHHEEEEEEE
QGLSESQIQSKGTNSATYTNLSPGDYIFSIYAIDPVTGKKGQIRELNIEITPPWWLSITA
CCCCHHHHHHCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCHHHHHHH
KFIYLLCFIFISILIIKTILRRREIQRQIAKSEERLKLSLWGSGDEMWDWDIETGQIYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCEEEEC
NIWGSLEFPQDGQRSGNNGEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKSNDW
CCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCE
VWILDRAKIVERDENDNALRMTGTIKNISNFKQAEEQLRLFERAIQNISEGMFILDRNFK
EEEEECCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEE
FVEVNEACCDLSMMSKNELIGTLFNFDLYPDSYSEQIRSILKQQGRWNNEVESIRGNGSS
EEECCHHHCCHHHHCCHHHEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCE
FLMELSVDAIYDEQGELSHFVGVFSDVSRRKQQEEELRKLTNNDLLTNLPNRSNLMVTLG
EEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEC
NLVKRDSHHTLMVLDLDNFKKINDSLGHQAGDELLVQVSERIQVAVPSHTSIYRLGGDEF
HHHCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCEEEEECCCCEEEEECCCEE
AILVDKNPDIGTSAIIAKNVIHAFEASFELSSEKVVVGLSIGIVLYPEDDQNEQALLRKA
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHHHH
DIAMYHAKSAGGNRYQFYSESLNKNAIRQLEVENLIRDGLKDDLFEVYYQPKVDLKTGHM
HEEEEEECCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCH
AGMEALVRLNHPELGLIAPNEFIPLAEENGLIVEIGDVVLKKACFAAQKWRSQGLFNGRV
HHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEE
AVNLSSKQFALPDLQQRVESILRLTQLPAANLELEITEGTVIKEPEKAIKVMQQLSKMGV
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECHHHHHHHHHHHHHCCC
SLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVV
EEEECCCCCCHHHHHHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE
GEGVEDASQLSILRALKCEEIQGYIFSKPVTESKFTLLLQQDSNNQPMTALPAKRG
CCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEEECCCCCCEEECCCCCC
>Mature Secondary Structure
MLANNQTENMPRILIKIATFLLFCISMANSAYALTLNSTSLGVQDGLSQSNVTSIVEDAD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCHHHHHHHCCC
GYIWIGTVNGLNRYDGKEFRHYFPSKENELPSAFIRSLFISDTGVMYIGTDKGLAVYDSL
CEEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
TDRVISIKSGDFLKEQAIWSISDNGNEIIIGAENAVYITQENSKEAVLELLNSYSGDYNG
CCCEEEECCCCCCHHCEEEEECCCCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCHHH
VKQAIHFKNEIYIRNYIGEVKSIQNTHELYFQKATAIKEINNKLVVFTTDGIYEMANASF
HHHHHHHCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCC
SKKNNDSFISVSSGDGHFALKESAIYDISKLTSPLLIGTPSLSERELNLSRINIFRGLNK
CCCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCC
TFIAHQNEGVIIIDDNYNLIQSITNNIGNVWSISEDDENKILVTTEDSKLKLYNLEFELI
EEEEECCCCEEEECCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCEEEEEECHHHHH
KEYETGLYGNKSALTVDNNIYIASDLGLFSINKQTEVLSSVNQGSYFLLEKLNDGKTIVA
HHHHCCCCCCCCEEEECCCEEEEECCCEEEECCHHHHHHHCCCCCEEEEEECCCCCEEEE
GSSNGSILKYNTLDKSSKNIRIDRVNPIFDIQELNNSLYVGTQSGLYKVENNKTKIIYDE
ECCCCCEEEEECCCCCCCCEEEECCCCEEEHHHCCCEEEEECCCCEEEEECCCEEEEECC
NFVTSITKSGSSLYFGTSTGIKKYSTTRNSIEDVYSNKKPIFSLAINNQQLYASSINEVI
CCEEHHHCCCCEEEEECCCCCCHHCCCHHHHHHHHCCCCCEEEEEECCCEEEHHHHHHHH
IHNFKNTSTSILTNELGAQEEYNLQSILDNDSEVYIGGISGVSRIITKELNSFLERNTPP
HCCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
ITELTELSIFNIIEEPNGSVLKNQLSQTDKIKLKYSDYPFTLSFSSPGSSFKHINYVYQM
CHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCHHEEEEEEE
QGLSESQIQSKGTNSATYTNLSPGDYIFSIYAIDPVTGKKGQIRELNIEITPPWWLSITA
CCCCHHHHHHCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCHHHHHHH
KFIYLLCFIFISILIIKTILRRREIQRQIAKSEERLKLSLWGSGDEMWDWDIETGQIYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCEEEEC
NIWGSLEFPQDGQRSGNNGEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKSNDW
CCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCE
VWILDRAKIVERDENDNALRMTGTIKNISNFKQAEEQLRLFERAIQNISEGMFILDRNFK
EEEEECCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEE
FVEVNEACCDLSMMSKNELIGTLFNFDLYPDSYSEQIRSILKQQGRWNNEVESIRGNGSS
EEECCHHHCCHHHHCCHHHEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCE
FLMELSVDAIYDEQGELSHFVGVFSDVSRRKQQEEELRKLTNNDLLTNLPNRSNLMVTLG
EEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEC
NLVKRDSHHTLMVLDLDNFKKINDSLGHQAGDELLVQVSERIQVAVPSHTSIYRLGGDEF
HHHCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCEEEEECCCCEEEEECCCEE
AILVDKNPDIGTSAIIAKNVIHAFEASFELSSEKVVVGLSIGIVLYPEDDQNEQALLRKA
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHHHH
DIAMYHAKSAGGNRYQFYSESLNKNAIRQLEVENLIRDGLKDDLFEVYYQPKVDLKTGHM
HEEEEEECCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCH
AGMEALVRLNHPELGLIAPNEFIPLAEENGLIVEIGDVVLKKACFAAQKWRSQGLFNGRV
HHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEE
AVNLSSKQFALPDLQQRVESILRLTQLPAANLELEITEGTVIKEPEKAIKVMQQLSKMGV
EEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECHHHHHHHHHHHHHCCC
SLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVV
EEEECCCCCCHHHHHHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE
GEGVEDASQLSILRALKCEEIQGYIFSKPVTESKFTLLLQQDSNNQPMTALPAKRG
CCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEEECCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]