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The map label for this gene is aroH [H]

Identifier: 157962372

GI number: 157962372

Start: 3104684

End: 3105751

Strand: Direct

Name: aroH [H]

Synonym: Spea_2551

Alternate gene names: 157962372

Gene position: 3104684-3105751 (Clockwise)

Preceding gene: 157962371

Following gene: 157962374

Centisome position: 60.0

GC content: 45.79

Gene sequence:

>1068_bases
ATGACCATTAAAACAGACGAACTCCGCACTTCCCTTTTATGTAAGGTAATTTCACCTGCACAACTCGCTTCTGAATATCC
TTTAACGCAAGATGCCGCTGACTACCTAGTTCAGCAACGTCATGAGGTCGAAGCCATTATTAATGGTGAAGACCAACGTT
TACTTGTGATTATTGGTCCTTGCTCAATCCATGACACAGAAGCGGCTCTAGATTACGCAAAACGCTTAGCTGAACTACAC
CAGCAATATAAAGATGATTTATGCATCTTAATGCGTGTCTATTTTGAGAAGCCTCGTACAACAGTCGGATGGAAAGGACT
TATCTCAGATCCTGATCTAGACGGTAGCTTTAGCCCTAATAAAGGCCTACGTAAAGCACGTCATCTACTGCAGCAGATCA
CTGAGCTTAAGTTACCTATCGCGACAGAGTTTCTCGATATGGTAAACGGCCAGTACATCGCCGATCTGATTACTTGGGGC
GCTATTGGTGCTCGTACGACTGAAAGTCAGATCCACCGTGAGATGGCTTCAGCGCTTTCTTGCCCTGTAGGCTTTAAAAA
CGGTACCGATGGTAATATCGATATCGCTGTTGATGCTGTTCGTGCCGCGCAAGCGCCGCACATCTTCTACTCTCCTGACA
AAGATGGTGCAATGGCGGTTTACCGTACTCACGGTAACCCTTATGGCCACATCATCTTACGTGGTGGCAAACAGCCAAAC
TACCATAGCGACGATATCGCAAAAGCTGCGGCTCAGCTTGATAGCGTCGGTGTGACTCAGAGAATGGTTGTTGATTTCAG
CCATGGCAATAGCCGTAAGATGCATAAAGAGCAGCTTAATGTCGCTGACTCAATCATGCAGCAAATGGCTAATGGCGAAA
CGGCTATCGCTGGCATTATGGCTGAAAGCTTTATCGAAGAAGGCAATCAAAAAGTGGTTGCAGGTGAAGAGCTCATCTAC
GGTAAGAGCATCACCGATGCTTGCATTGACTGGGAAGACTCAAAAGTCTTACTAAGTGATCTGGCTAAGGCTTCACGCGC
AAGAATAGAATTGCTTAAGCAAAAATAA

Upstream 100 bases:

>100_bases
TAGCCTCACTTTTAAGGCAATTGCCACTGTGCACAGCCAAACTATTAGTTATAATCCGAGGTAATCAGGCGATAGCCCAT
ACGAACGCTCGGTATTTTGA

Downstream 100 bases:

>100_bases
TTCGCTAACGCATATCTTATGCTTCAGCTTAATCTAGAAACGTACCCACTCACCGAGTCGGTACGTTTTTTTATATCTTA
AAATAGTTGTCTGTACATTC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTIKTDELRTSLLCKVISPAQLASEYPLTQDAADYLVQQRHEVEAIINGEDQRLLVIIGPCSIHDTEAALDYAKRLAELH
QQYKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFSPNKGLRKARHLLQQITELKLPIATEFLDMVNGQYIADLITWG
AIGARTTESQIHREMASALSCPVGFKNGTDGNIDIAVDAVRAAQAPHIFYSPDKDGAMAVYRTHGNPYGHIILRGGKQPN
YHSDDIAKAAAQLDSVGVTQRMVVDFSHGNSRKMHKEQLNVADSIMQQMANGETAIAGIMAESFIEEGNQKVVAGEELIY
GKSITDACIDWEDSKVLLSDLAKASRARIELLKQK

Sequences:

>Translated_355_residues
MTIKTDELRTSLLCKVISPAQLASEYPLTQDAADYLVQQRHEVEAIINGEDQRLLVIIGPCSIHDTEAALDYAKRLAELH
QQYKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFSPNKGLRKARHLLQQITELKLPIATEFLDMVNGQYIADLITWG
AIGARTTESQIHREMASALSCPVGFKNGTDGNIDIAVDAVRAAQAPHIFYSPDKDGAMAVYRTHGNPYGHIILRGGKQPN
YHSDDIAKAAAQLDSVGVTQRMVVDFSHGNSRKMHKEQLNVADSIMQQMANGETAIAGIMAESFIEEGNQKVVAGEELIY
GKSITDACIDWEDSKVLLSDLAKASRARIELLKQK
>Mature_354_residues
TIKTDELRTSLLCKVISPAQLASEYPLTQDAADYLVQQRHEVEAIINGEDQRLLVIIGPCSIHDTEAALDYAKRLAELHQ
QYKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFSPNKGLRKARHLLQQITELKLPIATEFLDMVNGQYIADLITWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIDIAVDAVRAAQAPHIFYSPDKDGAMAVYRTHGNPYGHIILRGGKQPNY
HSDDIAKAAAQLDSVGVTQRMVVDFSHGNSRKMHKEQLNVADSIMQQMANGETAIAGIMAESFIEEGNQKVVAGEELIYG
KSITDACIDWEDSKVLLSDLAKASRARIELLKQK

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=63.2947976878613, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=54.8850574712644, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788953, Length=327, Percent_Identity=50.4587155963303, Blast_Score=343, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6319726, Length=340, Percent_Identity=51.7647058823529, Blast_Score=342, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6320240, Length=344, Percent_Identity=47.6744186046512, Blast_Score=325, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39220; Mature: 39089

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKTDELRTSLLCKVISPAQLASEYPLTQDAADYLVQQRHEVEAIINGEDQRLLVIIGP
CCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEC
CSIHDTEAALDYAKRLAELHQQYKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFSPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
KGLRKARHLLQQITELKLPIATEFLDMVNGQYIADLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTDGNIDIAVDAVRAAQAPHIFYSPDKDGAMAVYRTHGNPYGHIILRGGKQPN
CCCCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCC
YHSDDIAKAAAQLDSVGVTQRMVVDFSHGNSRKMHKEQLNVADSIMQQMANGETAIAGIM
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AESFIEEGNQKVVAGEELIYGKSITDACIDWEDSKVLLSDLAKASRARIELLKQK
HHHHHHCCCCEEEECCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKTDELRTSLLCKVISPAQLASEYPLTQDAADYLVQQRHEVEAIINGEDQRLLVIIGP
CCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEC
CSIHDTEAALDYAKRLAELHQQYKDDLCILMRVYFEKPRTTVGWKGLISDPDLDGSFSPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
KGLRKARHLLQQITELKLPIATEFLDMVNGQYIADLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTDGNIDIAVDAVRAAQAPHIFYSPDKDGAMAVYRTHGNPYGHIILRGGKQPN
CCCCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCC
YHSDDIAKAAAQLDSVGVTQRMVVDFSHGNSRKMHKEQLNVADSIMQQMANGETAIAGIM
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AESFIEEGNQKVVAGEELIYGKSITDACIDWEDSKVLLSDLAKASRARIELLKQK
HHHHHHCCCCEEEECCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]